Psychiatric disorder

This trial tests whether combining cognitive behavioral therapy with social skills training helps young people with early-onset psychosis improve their symptoms and daily functioning. Participants receive either this combined therapy or a control program of psychoeducation and he…

This trial tests whether a specialized two-year early intervention service, called OPUS YOUNG, can improve daily and social functioning in adolescents aged 12-17 who have experienced a first episode of psychosis. Participants are randomly assigned to either OPUS YOUNG or standard…

This study tests an updated version of the BRITE app, called ViraBrite, which sends suicide safety planning materials and coping skills to teens when they are feeling high emotional distress. Twenty teens who have recently attempted suicide or had suicidal thoughts with a plan wi…

This trial tests four family-oriented counseling programs designed to support children and adolescents (ages 3-18) who have a parent with a mental illness or addiction. The programs range from brief therapy for children showing signs of distress to preventive sessions for those w…

This study tests a new group program called Forging New Paths for adults with serious mental illness who have also been involved with the criminal justice system. The program combines cognitive behavioral therapy with social learning techniques to reduce aggression and help peopl…

This study tests a smoking cessation program designed for adults with serious mental illness. Participants receive a combination of videogame-based physical activity, smoking cessation counseling, and the medication bupropion. The goal is to see if this approach is feasible and a…

This trial tests a therapy called Multisystemic Therapy for Emerging Adults (MST-EA) for young people aged 16–26 who have a mental illness and a recent arrest or jail release. The therapy is home-based and involves therapists and coaches working with the young adult and their fam…

This study tested whether brief or in-depth counseling could help people living with HIV in Zambia reduce unhealthy alcohol use and improve HIV treatment. 680 adults who were on HIV medication and had hazardous drinking plus mental health or substance use issues took part. Partic…

This study tests whether a 12-week occupational therapy program based on the Model of Human Occupation (MOHO) can improve life skills and quality of life in mentally ill offenders. Twelve male offenders from a prison in Chennai, India, will attend 24 structured therapy sessions o…

This study tested an experimental drug called XPro1595 in 208 people with early Alzheimer's disease who also had signs of brain inflammation. The goal was to see if the drug could improve memory, thinking, and daily function compared to a placebo over 24 weeks. Researchers also c…

This trial investigates whether replacing red or processed meat with pulses (like beans, lentils, and chickpeas) can improve markers of heart health and change the gut microbiome. Participants are adults aged 18-65 with unhealthy, sedentary lifestyles who eat at least three servi…

This study tested the safety of a new drug called KarXT in 173 adults with schizophrenia. Researchers slowly increased the dose to see how well participants tolerated it and whether food affected the drug. The main goal was to track side effects, with secondary measures looking a…

This study tested a weight-loss program called CoachToFit for 257 veterans with serious mental illness (like schizophrenia or bipolar disorder) who were obese. Participants used a smartphone app, an activity tracker, and a Bluetooth scale, and worked with a peer coach. The goal w…

This completed trial in Xishui, China, tested a community-based program for 3,571 adults aged 35 and older who were at high risk for COPD and had mental health symptoms. The program included lung function tests, digital mental health support, smoking cessation help, and health ed…

This study looked at whether providing mental health care to people who inject drugs can improve their mental health and reduce their risk of getting HIV or hepatitis C. Over 500 participants in Haiphong, Vietnam, received free psychiatric consultations, medications, and support …

This study tested a 12-month telephone-based nurse care program for 805 adults with depression and signs of opioid use disorder. Participants were randomly assigned to receive nurse support or usual care. The goal was to see if the program could improve treatment for opioid use a…

This study tested a program called PR-ESSENCE, which teaches teens and staff how to solve problems together. Twenty youth aged 12-17 with behavior issues in special treatment homes took part. The goal was to see if this approach reduces problem behaviors and improves daily life c…

This study tested whether a smartphone app designed for people with serious mental illness can help them quit smoking better than standard methods. Researchers enrolled 343 adults with conditions like bipolar disorder or schizophrenia who wanted to quit. Participants used either …

This trial tested a 9-month group program called Illness Management and Recovery (IMR) for 198 adults with schizophrenia or bipolar disorder. The program focused on helping participants set personal goals and manage their symptoms. Researchers measured changes in daily functionin…

This study looked at the long-term safety and tolerability of the drug MP-214 in 254 people with schizophrenia. Participants had already completed an earlier trial and continued taking MP-214 at flexible doses. The main goal was to track side effects over time.

This completed study tested an experimental drug called MP-214 in 512 people with schizophrenia. Participants took either a daily dose of MP-214 (3, 6, or 9 mg), an existing antipsychotic (risperidone), or a placebo for six weeks. The main goal was to see if MP-214 reduces schizo…

This study looked at a new drug called MP-214 in 38 adults with schizophrenia. The goal was to see how safe the drug is, how the body processes it, and whether it helps control symptoms. Participants took the drug for 12 weeks, and researchers monitored side effects and drug leve…

This study tested the long-term safety and effectiveness of a new daily pill called MP-214 in 125 people with chronic or elderly schizophrenia. Participants took either MP-214 or the existing drug risperidone for several weeks. The goal was to see if MP-214 is a safe and tolerabl…

This study looked at the long-term safety and effectiveness of an investigational drug called MP-214 in 42 adults with schizophrenia who were already taking other antipsychotic medications. The main goal was to see how many people had side effects. The study was completed and hel…

This study tested whether training community health workers in Vietnam to deliver depression care (screening, therapy, and medication management) improves provider skills and patient outcomes. Over 1,300 patients and providers from three provinces took part. The goal was to see i…

This study tested a program to help people with mental illness quit smoking. The program included brief advice from their mental health provider and phone calls offering support. Researchers enrolled 94 daily smokers from community mental health centers and measured how many quit…

This study tested whether a healthy eating (Mediterranean diet) and exercise program started before pregnancy could help obese women lose 5-7% of their weight and improve health for both mother and baby. Researchers enrolled 99 women who had a previous baby and were planning anot…

This study tested whether a trained peer recovery specialist could help low-income, minority individuals stick with their methadone treatment for opioid use disorder. 200 participants in Baltimore were assigned to either the peer-led support program or standard care. The goal was…

This study tested whether peer specialists—people who have serious mental illness themselves and are trained to help others—can effectively deliver two types of therapy: Cognitive Behavioral Social Skills Training (CBSST) and Social Skills Training (SST). The goal is to help vete…

This study tested whether a team-based care model can help people with both opioid use disorder and mental health issues like depression or anxiety. 254 adults in primary care received either full collaborative care for both conditions or just mental health support. The goal was …

This completed study tested whether a Mediterranean diet could improve metabolic syndrome markers in 30 hospitalized adults with psychiatric conditions. Participants followed either a Mediterranean diet or a standard hospital diet for 8 weeks, then switched. Researchers measured …

People leaving acute psychiatric care in Alberta often wait months for a follow-up appointment, which raises the risk of relapse and a return to hospital. This trial tests a low-cost program that sends daily supportive text messages based on cognitive behavioral therapy and pairs…

This trial tests whether a structured lifestyle program—combining exercise, healthy eating, cognitive training, and social activities—can slow cognitive decline in older adults at risk of dementia. Participants aged 60-80 with modifiable risk factors will be randomly assigned to …

This study tested whether mindfulness training can prevent relapse in people with psychosis. 152 participants who were in remission were randomly assigned to either mindfulness training or standard education. Researchers tracked them for 12 months to see who had a relapse.

This study tested a school-based program called Preventure in 3,900 Canadian teens. The program targets four personality traits linked to substance misuse, aiming to delay or prevent alcohol and drug use. Researchers also measured whether delaying substance use helps protect cogn…

This study tested whether a single 3-hour group therapy session based on Acceptance and Commitment Therapy (ACT) could prevent mental health disorders in 120 women recently displaced by war in Ukraine. The women had mild to moderate symptoms of anxiety or depression. The goal was…

This study tested a 12-week program called SSAGE that brings together adolescent girls, their brothers, and their parents to discuss gender roles, communication, and healthy relationships. The goal was to prevent anxiety, depression, and other mental health issues in girls who we…

This study tested a new cognitive behavioral skills program (CBI) delivered in the metaverse for people with depression and anxiety. 306 participants were split into three groups: one using virtual reality, one using a flat-screen device, and a waitlist group. The program taught …

This pilot study tests a 10-session group program called AgingUP, designed for adults aged 50 and older living with severe mental illness. The program uses cognitive-behavioral and self-compassion techniques to help participants challenge negative beliefs about aging and mental i…

This study tests whether using brain scans to guide transcranial magnetic stimulation (TMS) works better than standard head measurements for treating depression. Participants with major depressive disorder receive accelerated TMS, but they won't know if their treatment spot was c…

This study tests whether practicing MediYoga—a gentle form of yoga—through a smartphone app can improve sleep quality, lower blood pressure, and boost quality of life in people aged 65 and older who have hypertension. Participants will be randomly assigned to do 20 or 40 minutes …

This study looks at whether Tai Chi, a gentle moving meditation, can improve chronic insomnia in breast cancer survivors. About 90 women who have completed cancer treatment and have had trouble sleeping for at least 6 months will practice Tai Chi. Researchers will measure sleep q…

This study tested whether therapeutic horseback riding can improve behavior, social skills, and emotional control in 250 autistic youth who also have a mental health condition. Participants were randomly assigned to riding, barn activities without riding, or a hybrid group. Resea…

This study tests a 12-week supervised exercise program for adults with severe mental illness, such as schizophrenia, bipolar disorder, or major depression. The program combines cycling, strength training, and breathing exercises in twice-weekly sessions. Researchers will measure …

This study tested whether a computerized training program that targets emotional reactions can help relieve obsessive thoughts and compulsive behaviors in people with OCD. Five adults with OCD completed 14 training sessions over three weeks. The goal was to see if this approach c…

This trial tests whether adding virtual reality to cognitive behavioural therapy (CBT) can better reduce persecutory thoughts in people with schizophrenia spectrum disorders compared to traditional CBT alone. About 256 participants will receive either VR-assisted CBT or standard …

This study tests a mobile program called Compass for Care, designed to help people caring for a loved one with Alzheimer's or related dementias. The program delivers 12 weekly modules and tailored messages focusing on five self-care behaviors, such as taking time to recharge and …

This trial is testing a web-based app called Active Ease, designed to help people with severe mental illness living in residential care become more physically active. The app includes educational content and guided exercise demonstrations. Researchers will compare two residential…

This study tested whether a nasal spray medicine (dexmedetomidine) given before surgery could reduce negative behavior changes in children after surgery, compared to a standard oral medicine (midazolam). 324 children aged 2-5 years having tonsil surgery took part. Researchers tra…

This trial tests a 9-session mindfulness and compassion program, called Cuida2, in 5th and 6th graders. Students are randomly assigned to either the program or a relaxation-based control group. Researchers measure changes in emotional and behavioral problems, academic performance…

This study tested a 15-session program called 'Think and Cope Positively' for people with severe mental illness (like schizophrenia or bipolar disorder). The program uses techniques from cognitive behavioral therapy and positive psychology to increase positive emotions, optimism,…

This early-phase trial tests a new brain stimulation target for people with depression plus at least one other psychiatric disorder, such as anxiety, OCD, or PTSD. The treatment uses a non-invasive form of brain stimulation called accelerated intermittent theta burst stimulation …

This study tests two digital sleep interventions designed to help teenagers aged 12-14 improve their sleep regularity and mental health. Participants wear a Garmin device and use a smartphone app that provides personalized feedback on their sleep patterns. The goal is to see if t…

This study tests an experimental oral medication, ML-007C-MA, in 307 adults hospitalized with schizophrenia who are having a sudden worsening of psychosis. The goal is to see if the drug reduces symptoms like hallucinations and delusions better than a placebo. Participants take t…

This early study tests a new, personalized brain stimulation method (tACS) for depression during pregnancy. Ten women (5 with depression and 5 healthy) will receive the treatment to see if it is safe, tolerable, and practical. The goal is to gather initial data to guide larger fu…

This study tests an oral drug called SDX (serdexmethylphenidate) to see if it safely reduces excessive daytime sleepiness in adults with idiopathic hypersomnia, a condition where people feel extremely sleepy during the day despite getting enough sleep at night. Participants will …

This study tested whether a guided, telehealth-based aerobic walking program could improve thinking, mood, and quality of life in people who had a traumatic brain injury (TBI). Researchers enrolled 112 participants and measured changes in brain blood flow, walking ability, and me…

This study tested whether Collaborative Problem Solving (CPS), a behavioral approach that teaches caregivers to address children's underlying thinking skill deficits, can improve executive function and reduce behavioral symptoms in 54 youth receiving home-based mental health care…

This completed study tested a combination of music therapy, health education, and physical exercise in 20 older adults (over 60) living in Valencia who felt unwanted loneliness. The goal was to see if these group activities could reduce loneliness and improve mental health. Becau…

This study tested a program based on Acceptance and Commitment Therapy (ACT) for 64 caregivers of people with mental disorders. The program aimed to help caregivers build psychological resilience, manage stress better, and feel less burdened. Results showed that those who took pa…

This study tested a program to reduce anticholinergic medications (like benztropine) in 53 adults with schizophrenia, bipolar disorder, or other serious mental illnesses who had been taking these drugs for at least 6 months. The goal was to safely taper or stop these medications …

This study tested whether a 4-week program using active video games (exergames) on the Nintendo Switch could help adults with mental illness feel better and stay motivated. Twelve participants were split into two groups: one played exergames, the other continued their usual routi…

This study tested a new drug, centanafadine, in 337 adults with major depression who hadn't responded well to at least one prior treatment. Some participants took the drug alone, others added it to their current antidepressant. The main goal was to see if it reduced depression sy…

This study tested whether a 6-session educational program could help people receiving electroconvulsive therapy (ECT) feel less stigma and anxiety about their mental health treatment. Sixty adult inpatients with conditions like depression or bipolar disorder took part. Those who …

This study tested a new medicine called MK-8189 in 224 adults having an acute episode of schizophrenia. Participants received either MK-8189, a placebo (inactive pill), or an active control (risperidone) for 4 weeks. The main goal was to see if MK-8189 reduces schizophrenia sympt…

This study tested a digital aftercare program for 60 children and teens leaving psychiatric hospital care. The program used regular video calls and a secure smartphone messenger to connect patients, parents, and teachers with their hospital therapist. The goal was to ease the ret…

This study looked at whether creating personalized profiles for children with disruptive behavior disorders (like ADHD or oppositional defiant disorder) and their parents could help predict which therapy works best. Researchers tested two common treatments—child cognitive behavio…

This study tested an optimized multichannel tDCS (a non-invasive brain stimulation device) against standard and sham versions in 60 adults with moderate-to-severe major depression. The goal was to see if the new protocol better reduces depressive symptoms and improves memory and …

This study tested a new parenting program called ADAPT for depressed parents of children aged 6 to 10 with emotional and behavioral difficulties. The program combines emotion regulation skills with parenting techniques. The goal was to see if the program is feasible and acceptabl…

This study looked at behavior problems in 101 children aged 3 to 6 with tuberous sclerosis complex (TSC). Families completed assessments online, and those with elevated behavior issues were offered a parent-training therapy (PCIT) over the internet. The goal was to help parents m…

This study tested whether a simple writing therapy, done over video calls, could help prevent or reduce PTSD in women who recently experienced sexual assault. Thirty women who visited a Sexual Assault Nurse Examiner (SANE) clinic within 7 days of the assault took part. The therap…

This study tested whether an eight-session expressive arts therapy program could increase hope in 50 hospitalized adults with schizophrenia. Participants in the therapy group showed significantly higher hope scores compared to those receiving standard care alone. The findings sug…

This study tested whether a gentle electrical current applied to the scalp (tDCS) can reduce symptoms of major depression, schizophrenia, OCD, generalized anxiety, and insomnia. 320 adults aged 16–65 received multiple sessions over weeks. Researchers measured symptom changes usin…

This study tested whether adding an experimental drug called SEP-363856 to standard antidepressants can better reduce depression symptoms in adults who didn't respond well to prior treatments. About 929 participants took either the drug or a placebo alongside their usual medicati…

This study tested a telehealth program that teaches caregivers skills to manage ADHD-related behaviors and sleep problems in preschoolers aged 3-5 at risk for ADHD. 46 families participated, and researchers measured changes in ADHD symptoms and sleep habits. The goal is to provid…

This study tested a 10-week peer support program called 'Paths to everyday life' for adults with mental health difficulties. Participants were randomly assigned to either the peer support group plus usual services, or usual services alone. The goal was to see if the program impro…

This pilot study tested whether music therapy could improve hope, quality of life, and social functioning in 12 people with severe mental illness living in the community. Participants chose music to listen to during 12 sessions over 20 weeks, followed by a conversation with a nur…

This study tested the Triple P parenting program for mothers of children aged 6-13 with ADHD. The program teaches strategies to reduce behavior problems and boost mothers' confidence. 67 mothers took part, with some receiving the program and others not. Researchers measured chang…

This early-phase trial tested the safety of nabilone, a synthetic cannabinoid, in 20 adults with intellectual and developmental disabilities who have severe aggression. The goal was to see if the drug is well-tolerated and to gather initial data on whether it might reduce aggress…

This study tested whether an Apple Watch paired with a special app and weekly health coaching could help dementia caregivers improve their sleep and mood. Twenty-one caregivers wore the watch to track their activity and sleep, and received personalized feedback and motivational c…

This study tested whether a non-invasive brain stimulation technique called tDCS can help people with schizophrenia whose symptoms persist despite medication. 141 adults received either real or sham tDCS over 10 sessions. The goal was to see if active stimulation leads to a meani…

This study tested a type of talk therapy called Positive Psychotherapy (PPT) to help people with serious mental illness quit smoking. Sixteen adults who smoked at least 10 cigarettes a day and wanted to quit took part. The goal was to see if at least 20% could stop smoking comple…

This study tested whether qigong relaxation exercises can lower anxiety and depression in adults hospitalized for depression. 70 patients participated in a randomized controlled trial. The goal was to see if adding qigong to standard care improves mood and reduces anxiety symptom…

This study tested a short-term talking therapy (psychodynamic psychotherapy) for 24 adults with advanced solid tumors and high psychological distress. The goal was to see if the therapy is safe, acceptable, and feasible, not to cure the cancer. Results will help design larger stu…

This study tested whether a phone-based cognitive behavioral therapy program could help people with severe or morbid obesity reduce their food addiction. 154 participants received either 12 therapy sessions over 18 weeks or their usual care. The goal was to see if the therapy cou…

This study tested a 10-session dog-assisted therapy program for 60 adults with severe mental illness. The goal was to see if spending time with trained therapy dogs could help participants build positive mental health behaviors like communication and socialization. Researchers me…

This study tested two doses of a new drug called emraclidine (CVL-231) in 391 adults with schizophrenia who were having a sudden worsening of psychotic symptoms. Participants took the drug or a placebo daily for 6 weeks. The main goal was to see if the drug reduced symptoms like …

This study tested whether a mobile app called Messy Memories could help people who had been in the intensive care unit (ICU) deal with distressing memories. The app guides users to record and process a difficult memory on their own. Researchers wanted to see if people would actua…

This study tested a group version of a therapy program called UP-A for 15 teenagers with severe emotional disorders like anxiety and depression. The teens were treated at a day hospital in Spain. The program aimed to help them manage their emotions and reduce symptoms. Researcher…

This Phase 2 trial tested two doses of emraclidine (10 mg and 30 mg daily) against a placebo in 385 people with schizophrenia who were having a sudden worsening of psychotic symptoms. The study lasted 6 weeks and measured symptom changes using a standard rating scale. The goal wa…

This study tested whether cannabidiol (CBD) oil can reduce severe behavioral problems in children aged 6-18 with intellectual disability. 132 participants received either CBD or a placebo for 8 weeks. The main goal was to see if CBD improves irritability and other challenging beh…

This pilot study adapted a behavioral intervention called BECOME to help people with dementia or mild cognitive impairment and their caregivers manage non-communicable diseases (like diabetes and high blood pressure) and common mental health conditions (like depression and anxiet…

This study tests a training program called DECIDE for MOM, designed to help healthcare providers better support pregnant and postpartum individuals with mental health concerns. The training teaches skills like shared decision-making and understanding patients' perspectives. Resea…

This study aims to understand how common depression and anxiety are among parents involved with Swedish child welfare services due to child maltreatment or other family risks. Parents will fill out questionnaires about their symptoms and background. The results will be compared w…

This study tests a new approach called the Collaboration-Screening-Referral (SSH) model, which aims to identify parents involved with child welfare services who may have depression or anxiety. Social workers will be trained to use screening questionnaires and refer parents to men…

This study tested whether an AI-powered smartwatch could help teenagers and young adults with mental health conditions stick to their medication schedule. Researchers compared medication adherence in 78 people who wore the watch to those who did not. The goal was to see if the wa…

This study looks at whether spending 2 to 3.5 weeks at a device-free summer camp in Maine can improve mental health and brain activity in teens aged 12 to 17. Researchers will measure changes in mental health scores and brain waves (EEG) from the start to the end of camp. The goa…

This study explores whether two non-invasive measures—fat in the liver and thickness of the carotid artery—can serve as early warning signs of heart and metabolic problems in children treated with antipsychotic medications. Researchers will compare these measures in children on a…

This study looks at whether having certain E. coli bacteria in the colon after colorectal cancer surgery is linked to anxiety or depression. Researchers will compare psychiatric symptoms and diagnoses between patients who carry the bacteria and those who do not. The goal is to be…

This study looks at how often people who visit a community psychiatrist have had suicidal thoughts in the two weeks before their appointment. Researchers will ask about 262 adults to fill out questionnaires measuring suicidal risk, psychological pain, and self-esteem. The goal is…

This study explores whether a radio drama can shift negative attitudes toward mental illness in rural Uganda. Researchers will measure stigma levels among community members, traditional healers, religious leaders, and families of those with mental illness. The drama is adapted fr…

This study explores the experiences of people diagnosed with a psychiatric disorder who have used psychedelic substances on their own to relieve symptoms. Researchers will conduct in-depth interviews with 20 participants to understand their motivations, methods, and perceived eff…

This pilot trial tests whether adding social contact — personal stories and interactions with people who have mental illness — to standard mental health training can reduce stigma among primary care workers in Nepal. About 88 healthcare providers and their patients will take part…

This study looks at how mepolizumab (Nucala), a treatment for severe eosinophilic asthma, impacts emotions and mental well-being in patients and their partners. Researchers will track changes in feelings like anxiety, depression, and stress using questionnaires and interviews. Th…

This study looks at whether people with dyssynergic defecation—a condition where the pelvic muscles don't relax properly during bowel movements—are more likely to have psychiatric disorders like anxiety or depression. Researchers will compare 148 patients to healthy volunteers us…

This completed study looked at how well a collaborative care model works for common mental health issues like anxiety and depression in four French health clinics. The model involves a care manager who coordinates between family doctors and mental health specialists. Researchers …

This study looked at over 30,000 adults admitted to hospitals in Maryland to understand why some patients wait in the emergency room even after being admitted (called boarding). Researchers wanted to find out what patient traits lead to longer waits, how boarding increases health…

This study tested whether a 10-week recovery program, co-led by a peer with mental illness and a professional, is feasible for people with mental illness in Taiwan. Twenty participants completed the program, which focused on recovery concepts, strengths, and goal setting. Researc…

This completed study looked at how the COVID-19 pandemic and social distancing impacted the mental health of 259 adults with chronic inflammatory rheumatism (like rheumatoid arthritis or ankylosing spondylitis). Researchers used questionnaires to measure stress, depression, anxie…

This study looked at 124 teens aged 12-18 with serious mental health conditions to see if community-based treatment (Child ACTT) works better than a psychiatric residential facility. Researchers measured well-being using a standard questionnaire. The goal was to find out which se…

This study looked at whether a therapy called FAST (Forensic Outpatient Systemic Therapy) helps teens aged 12-21 with conduct disorder or aggressive behavior. The therapy involves weekly sessions with the teen and their caregivers for several months. Researchers measured changes …

This study tested whether artificial intelligence (AI) can realistically simulate conversations between a therapist and a person with a mental health problem. Researchers used 520 simulated sessions to see if the AI could follow proper therapy techniques. The goal is to use these…

This study looked at how thinking skills and brain activity differ in people who self-harm compared to those who don't. Researchers interviewed 316 adults and gave them thinking tests, with some also having brain scans. The goal was to better understand self-harm to help create m…

This study looked at whether a new educational program helps doctors-in-training better recognize and respond to child maltreatment. 84 medical residents from Canadian universities took part. The program was delivered either in a group with a leader or on their own. The goal was …

This completed study in Norway looked at whether delaying school start times by one to two hours on Mondays and Tuesdays helps high school students sleep longer, feel less sleepy during the day, and improve their mental health and grades. Over 580 first-year students participated…

This study tested whether a digital symptom checker could work as well as a traditional phone call for guiding patients to the right level of care. Researchers planned to include 120 adults from a primary care center, but only 22 took part. The main goal was to see if a larger tr…

This study looked at the relationship between mental health case managers and people with severe mental health disorders. Researchers worked with 26 participants to understand how this bond can help recovery. They used group discussions and surveys to measure the quality of the r…

This study tested a program called Recovery Bridge, where trained peer specialists (people with lived experience of mental illness) helped veterans leaving a psychiatric hospital connect to outpatient care and community life. Fifteen veterans took part to see if the program was f…

This study looked at how anonymity and data privacy affect the success of online therapy for social anxiety. Over 450 adults used either a fully anonymous or a standard version of a digital self-help program. The goal was to see if privacy options change how well the therapy work…

This study looked at whether digital services like smartphone apps can help people with psychosomatic disorders continue their treatment during the COVID-19 pandemic, when social distancing and hygiene rules limit in-person therapy. About 2000 patients from clinics took part, usi…

This study tested a program for people with long-COVID that includes an online screening, a detailed in-person assessment, and digital training modules with a personal counselor. 192 participants from Bavaria took part to see if this approach is practical and helpful. The goal wa…

This completed study looked at 400 people with both heart disease and a mental health condition (like depression or anxiety). Researchers used questionnaires, blood tests, and imaging to find shared risk factors and biological markers. The goal was to better understand how these …

This study tested whether an anti-stigma training program for healthcare providers improves attitudes toward people with mental illness or substance use problems. About 485 staff and clients from six health centers took part, with three centers receiving the training and three no…

This study looked at how often insomnia occurs in people hospitalized for psychiatric conditions. Researchers checked 427 patients at 11 hospitals in Switzerland and Germany. They also explored whether age, gender, or type of disorder made insomnia more likely.

This study looked at the mental health of hospital staff and medical students after the 2016 Nice terrorist attack. Researchers surveyed 804 people to understand how the event affected them and to find better ways to support caregivers in future crises. The goal was to learn, not…

This study looked at whether a program called MISSION-CJ can help homeless veterans who have both substance use and mental health problems stay out of trouble with the law. 134 veterans took part, and researchers tracked arrests, substance use, housing, and employment. The goal w…

This study tested a program called CRAFT-EP, which helps families support a relative with early psychosis and substance use (like alcohol or cannabis). The program was delivered entirely through video calls. Researchers measured family members' depression and anxiety to see if th…

This study looked at how to keep mental health programs running in 12 urban public schools with limited resources. Researchers compared two support models for school counselors and staff delivering evidence-based programs like Coping Power and CBT for anxiety. Over three years, t…

This study tested a remote training program to help school staff in rural areas deliver mental health support to students. Researchers worked with 174 school staff to see if the training was practical and effective. The goal was to improve access to care in places with few mental…

This study examined anxiety, depression, fatigue, and quality of life in 20 adults with Behçet's disease using questionnaires. Researchers aimed to understand the psychological symptoms that often accompany this rare inflammatory condition. The study was observational and did not…

This pilot study tested an automated phone system called 'My Coach Connect' for people with chronic mental illness. Participants called in twice a week to answer questions about how they were doing. The goal was to see if the system was easy to use and helpful for both patients a…

This study tested an 8-month program called 'Meaningful Activities and Recovery' (MA&R) for people with mental illness. The program helps people take part in activities that matter to them. 139 adults took part to see if the program improves activity engagement, recovery, and qua…

This study tested an online training for pediatric primary care staff to improve how they refer parents to parenting programs. The goal was to increase enrollment in programs like GenerationPMTO, which can prevent child behavior problems. Researchers measured changes in staff com…

This study tested a 16-week program to help people with severe mental illness, like schizophrenia or bipolar disorder, sit less and move more. Participants met weekly to plan walking routes and received phone support. The goal was to see if the program was practical and could red…

This study tested whether people with hypopituitarism (a condition where the pituitary gland doesn't work properly) have lower oxytocin levels compared to healthy individuals. Researchers gave participants a drug called exenatide (a GLP1 receptor agonist) to see if it could stimu…

This completed study tested a new radioactive tracer called [18F]-SynVesT-1 to measure brain synapse density in 134 people with Alzheimer's disease, frontotemporal degeneration, dementia with Lewy bodies, or late-life psychiatric disorders. Researchers compared this new scan to t…

This study tested whether training staff in residential facilities can help prevent suicide and improve mental health for youth in the legal system. About 1000 youth and staff took part. Researchers compared facilities that received the special training to those that did not, mea…

This study interviewed 26 older adults (75+) with chronic illnesses who take many medications. Researchers wanted to understand how patients feel about being cared for by the same doctor over time, and what happens when they lose that regular doctor. The goal was to learn about t…

This study tested whether a systematic phone call from a medical student, supervised by a general practitioner, could reduce hospitalizations in patients with chronic heart or mental health conditions during the COVID-19 lockdown in France. Over 22,000 patients aged 70 and older …

This study tested a program where trained peer coaches (people who have their own experience with mental illness) helped 16 young adults (ages 18-30) with serious mental illness make decisions about joining community activities like work, school, or social events. The goal was to…

This study looked at whether asking patients for regular feedback during therapy can help clinics see more people and reduce waiting times. Researchers compared two psychiatric clinics in Sweden—one that used feedback-informed therapy and one that did not—using data from over 200…

This study aimed to find factors that can predict whether someone will develop post-traumatic stress disorder (PTSD) after a traumatic event like a serious injury or violence. Researchers followed 460 adults who came to the emergency room within a month of trauma and were at mode…

This study looked at 48 older adults having heart bypass surgery to see if a small molecule called microRNA-151-5p is linked to memory and thinking problems after the operation. Researchers measured levels of this molecule and inflammation in the blood before and after surgery, a…

This study used artificial intelligence to predict how engaged people would be in online therapy and how much their symptoms would improve. Researchers analyzed data from over 6,600 adults who took part in a digital psychotherapy program. The goal was to create fair and accurate …

This completed study looked at 224 adults who already had at least one psychiatric condition to see how many also had undiagnosed ADHD. Researchers measured how often ADHD was missed and tracked quality of life in those diagnosed. The goal is to highlight the need for better dete…

This study tested whether combining a policy change with professional training can reduce stigma toward substance use in mental health clinics. Twelve providers from two sites participated. The goal was to see if the combined approach improves how often substance use is addressed…

This study looked at how to make mental health care more available in Sub-Saharan Africa. Researchers worked with 901 clinic staff in Mozambique to train local health workers and use existing community programs. The goal was to find cost-effective ways to help more people get the…

This study looked at how a tiny, painless electric current to a part of the brain called the amygdala affects how people process emotions. Sixteen adults with epilepsy who already had brain electrodes in place viewed positive, negative, and neutral images while receiving random s…

This completed study looked at how often thinking, memory, and behavior problems happen after a stroke. Researchers tested over 1600 people, including stroke patients and healthy volunteers, using a French version of a standard cognitive battery. The goal was to better understand…

This study tested a system where police officers can call a mental health provider during encounters with people who have serious mental illness. The goal was to see if this reduces arrests and helps people stay connected to care. Over 1,400 participants were randomly assigned to…