Could beans and lentils beat red meat for a healthier heart?
NCT ID NCT05999136
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This trial investigates whether replacing red or processed meat with pulses (like beans, lentils, and chickpeas) can improve markers of heart health and change the gut microbiome. Participants are adults aged 18-65 with unhealthy, sedentary lifestyles who eat at least three servings of red or processed meat per week. They are assigned to either keep their usual diet, swap red meat for pulses, or swap red meat for a mix of pulses and plant-based meat substitutes. The study measures changes in cholesterol, blood TMAO levels, and gut bacteria over time.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
pulses (beans, lentils, chickpeas, peas)
What this could lead to
If swapping red meat for pulses improves cholesterol and gut health, it could point toward a simple dietary change to lower heart disease risk.
What could go wrong
This is a small dietary intervention study, not a drug trial. Results may vary by individual and may not show clear benefits. Long-term adherence to the diet is uncertain.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for LIFESTYLE-RELATED CONDITION are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Department of Agricultural Sciences, Federico II University
Portici, 80055, Italy