HIIT may boost muscle sugar storage and cut liver fat in type 2 diabetes

NCT ID NCT06688461

Recruiting now Disease control Sponsor: Finis Terrae University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether 12 weeks of high-intensity interval training (HIIT) can improve how muscles store sugar (glycogen) and use insulin in people with type 2 diabetes. Researchers will also check if HIIT reduces liver fat. The trial involves 36 overweight or obese adults aged 45-75 with type 2 diabetes. Participants will do HIIT three times per week, and their insulin sensitivity and liver fat will be measured before and after the program.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: High-intensity interval training (HIIT) exercise program
What this could lead to: If it works, this could show that HIIT is a better exercise strategy to improve blood sugar control and reduce liver fat in type 2 diabetes patients.
What could go wrong: This is a small, early-phase study with only 36 participants. The results may not apply to all people with type 2 diabetes, and the exercise program may be too intense for some.

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Conditions

The condition(s) this trial relates to.

Insulin Resistance psychiatric disorder type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INSULIN SENSITIVITY/RESISTANCE LIFESTYLE-RELATED CONDITION TYPE 2 DIABETES

Contacts and locations

Locations

Finis Terrae University
RECRUITING

Santiago, Chile

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