Could a better tDCS protocol lift depression?
NCT ID NCT06165445
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested an optimized multichannel tDCS (a non-invasive brain stimulation device) against standard and sham versions in 60 adults with moderate-to-severe major depression. The goal was to see if the new protocol better reduces depressive symptoms and improves memory and attention. The trial is complete, and results may guide future depression treatments.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
transcranial direct current stimulation (tDCS)
What this could lead to
If successful, this could lead to a more effective, non-invasive brain stimulation protocol for easing depression symptoms and improving thinking skills.
What could go wrong
This is a small, completed trial with 60 participants. The results may not apply to everyone, and the benefits over existing treatments are uncertain.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Zanjan University of Medical Sciences
Zanjan, Zanjan Province, Iran