Walking your way to a better brain after injury?

NCT ID NCT04243226

Completed Symptom relief Sponsor: National Defense Medical Center, Taiwan Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a guided, telehealth-based aerobic walking program could improve thinking, mood, and quality of life in people who had a traumatic brain injury (TBI). Researchers enrolled 112 participants and measured changes in brain blood flow, walking ability, and mental health. The goal was to develop a safe exercise plan that TBI patients could follow at home.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: telehealth-based aerobic walking exercise
What this could lead to: If it works, this could point toward a safe, accessible exercise program to help TBI patients think more clearly, feel less depressed, and enjoy a better quality of life.
What could go wrong: This is a completed early-stage study with 112 participants, so results may not apply to all TBI patients. Exercise benefits can vary, and the study relied on self-reported and device-based measures.

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Conditions

The condition(s) this trial relates to.

psychiatric disorder traumatic brain injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARDIOLOGY PSYCHIATRY

Contacts and locations

Locations

TSGH

Taipei, Taiwan

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