Can a diabetes drug reveal hidden hormone deficiencies?

NCT ID NCT04897802

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether people with hypopituitarism (a condition where the pituitary gland doesn't work properly) have lower oxytocin levels compared to healthy individuals. Researchers gave participants a drug called exenatide (a GLP1 receptor agonist) to see if it could stimulate oxytocin release. The goal was to better understand oxytocin deficiency in these patients, not to treat it.

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Conditions

The condition(s) this trial relates to.

central diabetes insipidus Combined Pituitary Hormone Deficiency diabetes insipidus Diabetes Insipidus, Neurogenic hypopituitarism hypothalamic disorder mental disorder panhypopituitarism pituitary gland disorder psychiatric disorder Social Isolation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hospital de la Santa Creu i Sant Pau

    Barcelona, 08041, Spain