CBD oil studied as a treatment for severe behavioral issues in kids with intellectual disability

NCT ID NCT04821856

Completed Symptom relief Sponsor: Murdoch Childrens Research Institute Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tested whether cannabidiol (CBD) oil can reduce severe behavioral problems in children aged 6-18 with intellectual disability. 132 participants received either CBD or a placebo for 8 weeks. The main goal was to see if CBD improves irritability and other challenging behaviors, as measured by a parent questionnaire.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: cannabidiol (CBD) oil
What this could lead to: If it works, this could provide a new treatment option for severe behavioral problems in children with intellectual disability.
What could go wrong: This is a phase 2 trial with a moderate size (132 participants). The results may not be strong enough to confirm effectiveness, and CBD may cause side effects or interact with other medications.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

intellectual disability psychiatric disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHILD BEHAVIOR PROBLEM INTELLECTUAL DISABILITY

Contacts and locations

Locations

Monash Children's Hospital

Clayton, Victoria, 3168, Australia
Royal Children's Hospital / Murdoch Children's Research Institute

Parkville, Victoria, 3052, Australia
The Children's Hospital at Westmead

Westmead, New South Wales, 2145, Australia

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