INTELLECTUAL DISABILITY

This study tests whether metformin, a diabetes medication, can help reduce weight gain caused by antipsychotic drugs in adults with intellectual or developmental disabilities. About 100 participants will receive either metformin or a placebo for several months. The goal is to fin…

This study is testing whether adding hands-on cooking classes to a standard weight management program helps young adults with intellectual disabilities lose more weight and maintain that loss over two years. Researchers will compare a group receiving the standard program with a g…

This study looks at whether letting people with intellectual or developmental disabilities use their preferred way to communicate (like a touch talker or picture cards) helps them stick with positive behaviors and reduces the chance of challenging behaviors returning. About 60 pa…

This study looks at whether playing digital brain games can improve visual memory and thinking skills in young adults (ages 18-35) with mild or moderate intellectual disabilities. Sixty participants will be split into two groups: one plays games using the MentalUP app, the other …

This study looks at bladder and bowel problems in children aged 5 to 12 with intellectual disabilities, and how these issues affect their participation in daily activities and their family's quality of life. Researchers will compare 100 children with intellectual disabilities to …

This study follows up to 150 people with MEHMO syndrome or related disorders to learn how the disease progresses. Researchers will collect blood, urine, spinal fluid, and skin samples, along with imaging and health checks. The goal is to find biological markers that could help di…

This study tests a job support program called IPS-AUT for autistic adults aged 18-40 who are not working but want a job. Researchers will train employment agencies and track whether participants get and keep jobs. The goal is to see if the program is practical and helpful, with a…

This study tests a program called PACE that helps adults with intellectual disability become more physically active. About 120 adults, along with their caregivers and coaches, will take part. The program focuses on increasing daily steps and moderate-to-vigorous activity, and the…

This study tests whether a one-time online lesson can improve how researchers think about and include people with disabilities in their studies. About 200 researchers will take the course, and their knowledge and attitudes will be measured before and after. The goal is to make re…

This study compares brain activity and pain responses between people with intellectual disability (ID) and healthy volunteers. Participants aged 8 to 30 will receive mild heat, cold, brushing, or electrical stimuli while wearing a brain-monitoring cap. The goal is to better under…

This study is tracking up to 1,000 people with certain genetic changes that affect brain development. Researchers will collect medical records, school reports, and do tests on behavior, movement, and sleep. The goal is to better understand these conditions, not to test a new trea…

This study aims to create and test a simple scale that caregivers can use to detect common eye disorders in adults with intellectual disability. Currently, no such tool exists, leading to delayed diagnosis. Researchers will work with 1,400 caregivers and adults with intellectual …