INTELLECTUAL DISABILITY

This study is testing whether adding hands-on cooking classes to a standard weight loss program helps young adults with intellectual disabilities lose more weight and keep it off. Over two years, researchers will compare weight loss, health markers, and daily living skills betwee…

This study is testing if using a person's favorite way to communicate (like a tablet app or picture cards) helps reduce challenging behaviors more effectively and for longer than a less-preferred method. It involves 60 people with autism or intellectual disabilities who have litt…

This study is testing whether the common diabetes drug metformin can help adults with intellectual disabilities lose weight they've gained from taking necessary antipsychotic medications. It's the first randomized trial specifically for this underserved group, who face high rates…

This study is testing a 16-week physical activity program called PACE for adults with intellectual disabilities. The program includes weekly group fitness classes, coaching sessions, and online resources. Researchers want to see if it helps participants become more active, improv…

This study is testing whether playing digital brain-training games can help improve memory and thinking skills in young adults with intellectual disabilities. Researchers will compare a group playing these games twice a week for a year to a group receiving their usual care. The g…

This study is testing a job support program designed to help autistic adults find and keep competitive jobs in their community. Researchers will work with 60 unemployed autistic adults aged 18-40 and their employment agencies to see if the program is practical, well-liked, and ef…

This study aims to better understand how specific genetic changes affect people's health and development over time. Researchers will observe and collect information from up to 1,000 individuals who have a confirmed genetic variant linked to conditions like autism, developmental d…

This study aims to better understand MEHMO syndrome, a rare genetic disorder causing intellectual disability, seizures, and other serious health problems. Researchers will observe 150 participants, including affected individuals and their family members, to track symptoms over ti…

This study aims to better understand the bladder and bowel problems that children with intellectual disabilities often face, and how these issues affect their daily activities and quality of life. Researchers will compare 100 children with intellectual disabilities to typically d…

This study is testing whether a short, one-time online training module can improve researchers' knowledge, attitudes, and willingness to include people with disabilities in their health studies. It will enroll about 200 researchers from medical centers. The goal is to identify an…

This study aims to understand how people with intellectual disabilities experience pain compared to those without. Researchers will measure brain activity, heart rate, and other responses while participants feel mild heat, cold, and touch sensations. The goal is to gather knowled…