Scientists probe pain in people with intellectual disability

NCT ID NCT05473429

Recruiting now Knowledge-focused Sponsor: National Institutes of Health Clinical Center (CC) Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jul 31, 2026 · Updated 8 times

Summary

This study compares brain responses to heat, cold, brushing, and mild electric shocks in people with and without intellectual disability. Researchers use brain scans and heart rate monitors to measure pain. The goal is to better understand how pain is felt in this group, especially for those who cannot speak.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help doctors better recognize and treat pain in people with intellectual disability who cannot communicate verbally.
What could go wrong: This is an early observational study, not testing a treatment. It may not lead to immediate changes in care, and results may not apply to all individuals with intellectual disability.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

intellectual disability

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INTELLECTUAL DISABILITY

Contacts and locations

Locations

National Institutes of Health Clinical Center
RECRUITING

Bethesda, Maryland, 20892, United States

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