Brain imaging may unlock early clues to autism in tuberous sclerosis
NCT ID NCT02461459
First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time
Summary
This study investigates whether advanced brain imaging and electrical recordings can predict the presence and severity of autism spectrum disorder (ASD) and intellectual disability (ID) in people with tuberous sclerosis complex (TSC). Researchers will follow participants over time, using yearly assessments and MRI scans to track brain structure and function. The goal is to identify biomarkers that could lead to earlier diagnosis and better understanding of these conditions in the context of TSC.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to earlier detection and better understanding of autism and intellectual disability in people with tuberous sclerosis complex, potentially guiding future treatments.
- What could go wrong
- This is an observational study, so it won't test a treatment. The findings may not apply to all individuals with TSC, and the biomarkers identified may not be definitive.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Boston Children's Hospital
Boston, Massachusetts, 02115, United States
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Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, 45229, United States
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Stanford University
Palo Alto, California, 94304, United States
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University of Alabama at Birmingham
Birmingham, Alabama, 35294, United States
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University of California at Los Angeles
Los Angeles, California, 90095, United States
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University of Texas at Houston
Houston, Texas, 77030, United States
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Other studies related to the condition(s) this trial covers.
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