INTELLECTUAL DISABILITY
Clinical trials for INTELLECTUAL DISABILITY explained in plain language.
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Diabetes drug tested as potential treatment for genetic disorder
Disease control CompletedThis study tested whether metformin, a common diabetes medication, could help people with Fragile X syndrome. For four months, 125 participants aged 6 to 35 took either metformin or a placebo pill. Researchers measured changes in language skills, behavior problems, and weight to …
Matched conditions: INTELLECTUAL DISABILITY
Phase: PHASE2 • Sponsor: University of Alberta • Aim: Disease control
Last updated Mar 23, 2026 15:14 UTC
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New genetic testing could solve mystery of unexplained intellectual disability
Diagnosis CompletedThis study compared two approaches to genetic testing for intellectual disability. Researchers tested whether whole genome sequencing (analyzing all genetic material from both parents and child) could find more causes of intellectual disability than current standard tests. The st…
Matched conditions: INTELLECTUAL DISABILITY
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Diagnosis
Last updated Apr 01, 2026 14:42 UTC
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New genetic tests aim to solve mystery of childhood developmental delays
Diagnosis CompletedThis study tested whether two new genetic diagnostic tools help doctors better identify the causes of intellectual disability and developmental delays in children. Researchers measured if pediatricians who learned about these tests ordered more appropriate treatments and fewer un…
Matched conditions: INTELLECTUAL DISABILITY
Phase: NA • Sponsor: Qure Healthcare, LLC • Aim: Diagnosis
Last updated Mar 11, 2026 14:54 UTC
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Texting and emails used as therapy to boost communication skills
Symptom relief CompletedThis study tested a 3-month program designed to help young adults with intellectual and developmental disabilities improve their reading and writing skills. Researchers taught strategies for understanding everyday texts like messages and emails. The goal was to see if this traini…
Matched conditions: INTELLECTUAL DISABILITY
Phase: NA • Sponsor: Baylor University • Aim: Symptom relief
Last updated Apr 01, 2026 14:41 UTC
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CBD oil studied to calm severe outbursts in disabled children
Symptom relief CompletedThis study tested whether a purified form of CBD (cannabidiol) oil could help reduce severe behavioral problems like aggression and irritability in children and teenagers with intellectual disability. Over 130 participants aged 6 to 18 were randomly given either CBD or a placebo …
Matched conditions: INTELLECTUAL DISABILITY
Phase: PHASE2 • Sponsor: Murdoch Childrens Research Institute • Aim: Symptom relief
Last updated Mar 24, 2026 12:02 UTC
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Cannabis-Based drug tested for calming severe aggression
Symptom relief CompletedThis early study tested the safety of nabilone, a synthetic cannabis-like medication, in 20 adults with intellectual disabilities who experience severe, frequent aggressive behaviors. Researchers wanted to see if the drug was well-tolerated and to check for any early signs it mig…
Matched conditions: INTELLECTUAL DISABILITY
Phase: PHASE1 • Sponsor: Hsiang-Yuan Lin • Aim: Symptom relief
Last updated Mar 20, 2026 14:48 UTC
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Playtime as therapy: can fun activities boost skills for kids with disabilities?
Symptom relief CompletedThis study tested whether a special program of play-based activities could help improve motor skills and daily living abilities in children with mild intellectual disability. Researchers worked with 20 Egyptian children aged 5-9, comparing those who received 24 sessions of therap…
Matched conditions: INTELLECTUAL DISABILITY
Phase: NA • Sponsor: Beni-Suef University • Aim: Symptom relief
Last updated Mar 16, 2026 15:25 UTC
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Researchers follow babies with seizures to uncover Long-Term development patterns
Knowledge-focused CompletedThis study followed about 280 children who had seizures as newborns to see how they develop over time. Researchers wanted to understand what factors might lead to developmental disabilities and whether parent well-being affects these outcomes. They tracked children's cognitive ab…
Matched conditions: INTELLECTUAL DISABILITY
Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Apr 01, 2026 22:56 UTC
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Scientists probe brain activity to unlock autism catatonia mystery
Knowledge-focused CompletedThis study explored whether brain scans and a non-invasive brain stimulation technique could help identify biological markers for catatonia in people with autism. Researchers worked with 26 participants aged 15-40 who have autism and catatonia symptoms. They used MRI scans to gui…
Matched conditions: INTELLECTUAL DISABILITY
Phase: PHASE1 • Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:34 UTC
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Researchers unlock best messages to get kids with disabilities tested for COVID at school
Knowledge-focused CompletedThis study aimed to find the best ways to encourage regular COVID-19 testing for children with intellectual and developmental disabilities (IDD) and their teachers to help keep schools safe. Researchers worked with over 1,100 participants from special schools in St. Louis and Bal…
Matched conditions: INTELLECTUAL DISABILITY
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:29 UTC
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Landmark study maps fitness journey for vulnerable children
Knowledge-focused CompletedThis study aimed to understand how physical fitness changes over time in children and teens with severe intellectual disabilities living in orphanages. Researchers followed 132 participants aged 7-18 for three years, measuring their strength and balance every few months. The goal…
Matched conditions: INTELLECTUAL DISABILITY
Sponsor: Xili Wen • Aim: Knowledge-focused
Last updated Mar 24, 2026 12:02 UTC