Study finds way to cut unneeded meds in mental health patients

NCT ID NCT07043803

Completed Symptom relief Sponsor: University of Pittsburgh Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a program to reduce anticholinergic medications (like benztropine) in 53 adults with schizophrenia, bipolar disorder, or other serious mental illnesses who had been taking these drugs for at least 6 months. The goal was to safely taper or stop these medications when they were no longer needed, which may improve memory and reduce side effects. The program used a stepped-wedge design across multiple healthcare sites to guide doctors and patients in reducing these drugs.

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Conditions

The condition(s) this trial relates to.

bipolar disorder psychiatric disorder Psychotic Disorders schizoaffective disorder schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BIPOLAR DISORDER PSYCHIATRIC DISORDERS SCHIZOAFFECTIVE DISORDER SCHIZOPHENIA DISORDER

Contacts and locations

Locations

Comprehensive Recovery Services (Pittsburgh) of Western Psychiatric Hospital, Ambulatory Clinics and Residential Programs - UPMC, Pittsburgh, PA

Pittsburgh, Pennsylvania, 15213, United States
UPMC Western Behavioral Health at Safe Harbor

Erie, Pennsylvania, 16508, United States
Western Behavioral Health Mon Yough

McKeesport, Pennsylvania, 16601, United States
Western Behavioral Health of the Alleghenies

Altoona, Pennsylvania, 16601, United States

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