Pfizer

This study is testing a new vaccine designed to protect against E. coli bacteria. The main goal is to check if the vaccine is safe and well-tolerated in 310 healthy adults. Researchers will give the vaccine as a shot and closely monitor participants for any side effects over a ye…

This study is testing a new vaccine, called VLA15, designed to prevent Lyme disease. It will enroll 200 healthy adults aged 18-44 to see how safe the vaccine is and how well it triggers an immune response when given on different schedules. Participants will receive four vaccine s…

This study is testing new mRNA-based flu vaccines to see how safe they are and how well they trigger the body's immune response. It involves about 770 healthy adults who will receive one shot and be followed for about 6 months. The new vaccines are being compared to currently app…

This large study is testing whether a new vaccine can prevent C. difficile infections, a serious cause of diarrhea, in adults aged 65 and older. About 32,000 participants will receive either the real vaccine or a placebo (saltwater) shot and be followed for up to 3.5 years. The m…

This study aims to measure how well Pfizer's 20-strain pneumonia vaccine protects adults 65 and older from severe, lung infection confirmed by chest imaging. It will enroll 12,500 participants who are hospitalized with suspected pneumonia. Researchers will compare infection rates…

This large study is testing whether a new vaccine given to healthy pregnant women can safely protect their newborns from Group B Strep (GBS), a serious bacterial infection. About 6,000 participants will receive either the vaccine or a placebo (saltwater) shot during pregnancy. Re…

This study is testing whether a new drug, PF-08634404, works better than the current standard treatment for people whose colorectal cancer has spread. About 800 adults who haven't yet received treatment for their advanced cancer will be randomly assigned to get either the new dru…

This study is monitoring the safety and real-world effectiveness of the antibiotic Zavicefta after its approval in Korea. It involves about 600 patients aged 3 months and older who are prescribed Zavicefta for serious infections like complicated abdominal infections, urinary trac…

This study is testing a new medicine called PF-08634404 for adults with advanced kidney cancer that has spread. Researchers want to see if the medicine is safe and effective when given alone or with other cancer drugs. The study is recruiting 224 adults who haven't received any t…

This program provides special early access to the drug etrasimod for patients with severe ulcerative colitis who have no other treatment options. It is for individuals who have tried and failed at least three other available therapies or cannot tolerate them. The program allows d…

This study is monitoring children aged 2-18 who are already taking Xeljanz for juvenile arthritis in routine Korean medical practice. Researchers will track their treatment experience for up to 44 weeks to understand the drug's safety and effectiveness in real-world use. This is …

This early-stage study aims to understand how the body absorbs a new weight management medicine when it's injected into different areas, like the thigh, arm, or abdomen. It will involve 54 adults who are overweight or have obesity, who will receive a single dose. Researchers will…

This study is testing a new weekly injection called MET097 to help adults with type 2 diabetes and overweight or obesity lose weight and better control their blood sugar. About 1,000 participants will receive either the real injection or a placebo (a shot with no medicine) for ab…

This early-stage study is testing whether two drugs—elranatamab (given as an injection) and iberdomide (taken as a pill)—can be safely combined to treat multiple myeloma that has returned or stopped responding to previous treatments. The trial will enroll 87 adults who have alrea…

This study is monitoring the safety and effectiveness of the approved eczema medication Cibinqo (abrocitinib) in real-world medical practice in Korea. It will follow about 1,100 patients, aged 12 and older with moderate to severe atopic dermatitis, for approximately one year afte…

This early-stage study is testing the safety and effects of an experimental cancer drug called PF-08046876 in adults with advanced solid tumors. The drug is an antibody drug conjugate designed to target and kill cancer cells. Researchers will give the drug through an IV to about …

This early-stage study is testing a new oral medication called PF-08032562, both alone and in combination with other cancer drugs, for people with advanced or metastatic breast or colorectal cancer. The main goals are to find a safe dose and see how the body processes the drug. R…

This study aims to see if a medicine called rimegepant can help prevent migraines in teenagers aged 12-17 who have chronic migraines (15 or more headache days a month). For the first 3 months, half the participants will take rimegepant every other day and half will take a placebo…

This study is monitoring the safety of Somatrogon, a growth hormone injection treatment for children with growth hormone deficiency in India. Researchers will follow 50 children aged 3 and older for up to 3 years to track any side effects they experience while receiving this trea…

This study is testing a new antibiotic combination (Aztreonam-Avibactam) for children hospitalized with serious bacterial infections. It aims to see how the drug works in the body, if it's safe, and if it helps clear infections compared to current standard treatments. The study w…

This study is testing whether a new injectable medicine, PF-07275315, can help control moderate-to-severe COPD. It will involve over 1,100 adults with COPD who have a history of serious breathing flare-ups. Participants will receive either the study medicine or a placebo shot ove…

This study is testing a new medicine called PF-08634404 when given alongside standard chemotherapy for adults with extensive-stage small cell lung cancer, a fast-spreading type of lung cancer. The research has two parts: first checking safety, then comparing the new combination t…

This study aims to see how well the medication etrasimod works for adults with moderate-to-severe ulcerative colitis in everyday, real-world settings. It will follow 300 patients for one year as they take the drug as part of their standard care. The main goal is to measure how ma…

This study is testing whether adding a new drug called Sigvotatug Vedotin to standard immunotherapy works better for advanced non-small cell lung cancer. It will involve 714 people with high levels of a specific protein (PD-L1) in their cancer cells. Half will get the new combina…

This study is testing the safety and how the body processes a new combination of two antibiotics (aztreonam and avibactam) in babies under 9 months old who have serious bacterial infections. The goal is to find the right dose and see if it's safe for this vulnerable age group. Th…

This study is testing whether adding an experimental drug called mevrometostat to a standard prostate cancer medicine (enzalutamide) works better than current standard treatments for men with advanced prostate cancer that has spread and is no longer responding to prior therapy. I…

This early-stage study is testing a new drug called PF-08052667 for adults with a type of bladder cancer that hasn't spread into the muscle but is likely to return. The drug is given directly into the bladder, either by itself or combined with other standard treatments. The main …

This study is testing a new oral medication called osivelotor for people with sickle cell disease. The main goals are to see if the pill can safely increase hemoglobin levels and reduce the number of painful crises (VOCs) that require medical care. The trial involves nearly 400 p…

This study is testing whether a new injection medicine called PF-07275315 can help adults with moderate-to-severe asthma that isn't well controlled by their current treatments. Over 12 weeks, 252 participants will receive either the actual medicine or placebo shots to compare saf…

This study continues testing an experimental medicine for pulmonary arterial hypertension (PAH), a serious condition where high blood pressure damages the heart and lungs. It follows 36 adults who already took the medicine in an earlier trial to check long-term safety and effects…

This study is testing a new oral medicine called ibuzatrelvir, given alone or with the IV drug remdesivir, to treat COVID-19 in adults with severely weakened immune systems. The goal is to see if these treatments are better than remdesivir alone at preventing severe outcomes and …

This study is testing a new medicine called elranatamab, given as a weekly injection, against several standard combination therapies for multiple myeloma that has come back or stopped responding to previous treatments. It will involve about 492 adults whose cancer has progressed …

This program provides early access to the investigational drug ritlecitinib for patients with severe alopecia areata who have lost at least 50% of their scalp hair. It's designed for people who haven't responded well to or can't tolerate other standard treatments available in the…

This study aims to see if adding an experimental drug called mevrometostat to the standard treatment enzalutamide works better for men with metastatic prostate cancer that still responds to hormone therapy. It will involve about 1,000 participants who have not yet received certai…

This study is testing whether a medicine called abrocitinib can safely and effectively control moderate-to-severe eczema in children aged 6 to under 12. About 150 children will be randomly assigned to receive either the real medicine or a placebo (a look-alike pill with no medici…

This study aims to evaluate the long-term safety and effectiveness of marstacimab, a preventive injection treatment, for people with severe hemophilia A or B. It includes about 245 participants, both children and adults, who have already been in previous marstacimab studies. The …

This study is testing whether a 5-day course of an oral medication called ibuzatrelvir can prevent people with mild-to-moderate COVID-19 from getting severely sick and needing hospital care. It is for adults and adolescents (12+) who have COVID-19 symptoms and are at high risk fo…

This is the first time a new drug called PF-07832837 is being tested in people. The main goal is to see if it is safe and how the body handles it. The study will involve both healthy volunteers and people with moderate to severe atopic dermatitis (eczema) to check for side effect…

This is a first-in-human study to test the safety and find the right dose of a new oral medicine, PF-07934040. It is being tested alone and in combination with other cancer drugs in people with advanced lung, colorectal, or pancreatic cancer that has a specific genetic change cal…

This study aims to learn about the long-term safety and effectiveness of the medicine ritlecitinib for treating severe alopecia areata, a condition that causes significant hair loss. It is for children and teenagers who have already finished one of two previous Pfizer studies for…

This study is testing whether new drug combinations can better control multiple myeloma that has returned or stopped responding to previous treatments. It will compare two experimental approaches using the drugs elranatamab and daratumumab against a current standard therapy. The …

This study is observing how well the drug tofacitinib works for people with ulcerative colitis in everyday Swedish healthcare. It will track about 120 adult patients who are already prescribed this medication by their doctor to see if it reduces their gut inflammation and symptom…

This two-year study aims to understand the long-term safety and effectiveness of an oral liquid medication called abrocitinib for children aged 2 and older with moderate-to-severe eczema (atopic dermatitis). It will enroll about 500 children globally, including some who have take…

This study aims to find out if a drug called Inotuzumab Ozogamicin works better than standard therapy for children with high-risk relapsed B-cell ALL. About 100 children aged 1 to 18 will receive one cycle of either treatment, then be followed for up to 5 years. The main goal is …

This study is testing whether a new drug (PF-07220060) combined with letrozole works better than current standard treatments for advanced breast cancer. It's for adults with a specific type of breast cancer that has spread and who haven't had any prior treatment for their advance…

This study aims to see how well and safely the oral medication abrocitinib works for adults with moderate-to-severe eczema in real-world doctor's offices, not just controlled trials. About 183 participants will take the pill daily for up to 24 months while doctors track their ski…

This study is testing an experimental drug called disitamab vedotin for people with advanced breast cancer that has spread and has a protein called HER2 on the tumor cells. It is for patients whose cancer has continued to grow despite receiving standard treatments, including othe…

This study provides continued access to the cancer drugs encorafenib and/or binimetinib for patients who were already taking them in earlier clinical trials and are still benefiting. It allows these patients to keep receiving the same treatment for up to about 5 years while docto…

This study is testing two new injectable medicines (PF-07275315 and PF-07264660) for adults with moderate-to-severe atopic dermatitis (eczema) who haven't gotten enough relief from skin creams. Participants will receive either one of the study medicines or a placebo (inactive sho…

This study is testing whether a medication called rimegepant can safely prevent migraines in children and adolescents aged 6 to 18. Researchers will compare the drug to a placebo (a pill with no medicine) to see if it reduces the number of migraine days each month over 12 weeks. …

This study is observing how well the oral medication abrocitinib works for people with moderate-to-severe eczema (atopic dermatitis) in real-world clinics. It focuses on about 150 patients aged 12 and older who did not get enough relief or could not tolerate up to two previous bi…

This study is testing a daily pill called etrasimod to see if it can help control the symptoms of moderate to severe ulcerative colitis in teenagers. It will involve about 36 participants aged 12 to 18 and will last for one year, with an option to continue for up to five years. T…

This study is testing whether a new daily pill (PF-07248144) combined with a standard hormone injection (fulvestrant) works better than current standard treatments for advanced breast cancer. It is for people whose cancer has continued to grow despite prior hormone-based therapy.…

This study is testing whether a new oral medicine, PF-07328948, is safe and can help control heart failure in adults who are already on standard treatments. About 620 participants will take either the study medicine or a placebo pill daily for 36 weeks. Researchers will measure i…

This study aims to better understand potential eye-related side effects in cervical cancer patients receiving TIVDAK treatment. Researchers will monitor 100 participants with recurrent or metastatic cervical cancer through regular eye exams before, during, and after their treatme…

This study is testing an oral medication called ritlecitinib to see if it can safely reduce itchy hives and swelling in adults with chronic spontaneous urticaria (CSU) that isn't controlled by standard allergy medicines. About 200 participants will be randomly assigned to take ei…

This study provides continued access to the drug elranatamab for people with multiple myeloma who benefited from it in earlier Pfizer-sponsored trials. It allows up to 80 participants to keep receiving the treatment while researchers monitor its long-term safety. The goal is to c…

This study is testing a new drug, PF-08634404, when used alongside other cancer medicines in adults with advanced non-small cell lung cancer that has spread. The main goals are to see if the drug combinations are safe and if they can help control the cancer. The study is in early…

This study aims to understand the long-term safety and effectiveness of the drug dazukibart for adults with dermatomyositis or polymyositis, two rare diseases that cause painful muscle weakness and inflammation. The trial is open to people who previously completed a related 52-we…

This study is testing if a new drug called PF-08046054 works better than the standard chemotherapy drug docetaxel for people with advanced non-small cell lung cancer. It is for adults whose cancer has spread, cannot be removed by surgery, and has gotten worse despite trying other…

This study is monitoring the safety and effectiveness of the arthritis medication Xeljanz XR in routine medical practice in Korea. It will follow at least 200 adults with rheumatoid arthritis, psoriatic arthritis, or ankylosing spondylitis who are already prescribed this medicati…

This study is testing a new drug called PF-08634404 to see if it is safe and effective for treating advanced liver cancer that cannot be removed by surgery. It will be given alone or combined with another drug (ipilimumab) to 138 adults who have not had other whole-body treatment…

This study is testing whether a new drug called PF-08634404, when combined with chemotherapy, works better than the current standard treatment (pembrolizumab with chemotherapy) for adults with advanced non-small cell lung cancer. About 1,410 participants will be randomly assigned…

This study aims to see if taking the medication rimegepant around the time of a woman's period can prevent menstrual migraines. It will involve about 723 women aged 18 to 45 who regularly get these migraines. The trial will compare rimegepant to a placebo (inactive pill) to measu…

This study is monitoring the safety and effectiveness of Litfulo capsules in real-world patients with severe alopecia areata (an autoimmune condition causing significant hair loss). It will enroll 3,000 patients in Korea who are already prescribed the medication to track side eff…

This study is testing whether a daily oral pill called ritlecitinib can safely reduce painful skin lumps in adults with moderate to severe hidradenitis suppurativa (HS), a chronic inflammatory skin disease. The 240 participants, whose HS did not improve with prior antibiotic trea…

This study aims to see how well the already-approved drug ritlecitinib works for people with the autoimmune hair loss condition alopecia areata in real-world, everyday medical practice. It will follow 850 patients aged 12 and older who are prescribed the drug by their doctor to m…

This study is testing whether a higher dose (100 mg) of the medication ritlecitinib is safe and works better than the standard 50 mg dose for treating severe alopecia areata, a condition that causes significant hair loss. It will involve about 550 participants aged 12 and older w…

This Phase 3 study is testing whether the investigational drug dazukibart can help control symptoms of dermatomyositis and polymyositis—rare autoimmune diseases that cause painful muscle inflammation and weakness. The trial will enroll 318 adults who are already taking standard m…

This early-stage study is testing a new oral medicine called PF-07799933, both alone and combined with other drugs, for people with advanced solid tumors that have a specific BRAF gene change and have stopped responding to standard treatments. The main goals are to find a safe do…

This study aims to monitor the safety and effectiveness of the drug Mylotarg in adults newly diagnosed with a type of blood cancer called acute myeloid leukemia (AML). It will observe 165 patients in Korea who are already receiving Mylotarg as part of their standard hospital care…

This study is testing whether a new injectable medication called PF-06835375 can safely increase platelet counts in adults with moderate to severe immune thrombocytopenia (ITP). Participants will receive monthly injections for 3-4 months while researchers monitor their platelet l…

This early-stage study is testing the safety of two new drug combinations for people with multiple myeloma that has returned or stopped responding to standard treatments. About 90 participants will receive either a three-drug combination or a two-drug combination to see how well …

This study is testing a new oral medicine called mevrometostat, alone and combined with an existing drug (enzalutamide), for men with advanced prostate cancer that has worsened despite prior treatment. The main goals are to find a safe dose and see if the treatment can help contr…

This large, late-stage study is testing whether adding a new drug called mevrometostat to a standard prostate cancer drug (enzalutamide) works better than the standard drug alone. It will involve 900 men with advanced prostate cancer that has spread and stopped responding to horm…

This large Phase 3 study is comparing two different drug combinations for people newly diagnosed with multiple myeloma who are not eligible for or are delaying a stem cell transplant. Researchers want to see if adding a new drug called elranatamab to a standard treatment is more …

This early-stage study is testing the safety and initial effects of a new oral medicine, PF-07799544, when taken with another drug, PF-07799933. It is for adults with advanced solid tumors, like melanoma or lung cancer, that have a specific genetic change called a BRAF V600 mutat…

This study is testing whether a daily pill called ritlecitinib can help regrow scalp hair in children aged 6 to 12 who have lost at least half their hair due to severe alopecia areata. About 225 children will be randomly assigned to receive either one of two doses of the study me…

This study is checking if it's safe for pregnant women to get a second dose of the RSV vaccine during a later pregnancy. It will also measure how long the protection from a single dose lasts. The study involves about 550 pregnant women who had the vaccine before and their babies,…

This study is testing whether a medication called rimegepant can safely and effectively relieve migraine pain in children and adolescents aged 6 to 17. Researchers will compare the drug against a placebo in 2,100 young participants who experience moderate to severe migraines. The…

This study aims to check the long-term safety of a migraine medicine called rimegepant in children and teenagers aged 6 to 18. Researchers will enroll 600 participants who experience migraines to monitor for side effects over time. The focus is on understanding how well young peo…

This early-stage study is testing the safety and how children's bodies process Zavegepant, a nasal spray medicine for migraine attacks. The trial includes 16 children aged 6-12 who have experienced migraines for at least 6 months. Researchers will give each child a single dose an…

This study is testing whether a new drug called ponsegromab can help people with advanced pancreatic cancer who are experiencing severe weight loss (cachexia). Participants will receive either ponsegromab or a placebo as an injection every four weeks, in addition to their standar…

This is an early safety study testing a new medicine called PF-07985631, which is being developed to treat a kidney disease called IgA nephropathy. The study involves 92 healthy adult volunteers who will receive either the study medicine or a placebo (inactive substance) via inje…

This study aims to prove that prazosin capsules, a blood pressure medication, work exactly the same whether they are made at a factory in Puerto Rico or one in Italy. Healthy adult volunteers will take capsules from each location so researchers can compare how the medicine is abs…

This early-stage study aims to understand how the body absorbs and processes different amounts of an experimental drug called atirmociclib when taken after a meal. It will involve 72 healthy adult volunteers who will take single oral doses of the drug. Researchers will measure th…

This study aims to understand how a common drug, carbamazepine, changes how the body processes an experimental Pfizer drug called PF-07248144. It involves 12 healthy adults who will take PF-07248144 alone and then with carbamazepine. Researchers will take blood samples to measure…

This early-stage study aims to understand how a new oral medicine called PF-07328948 is processed by the body in people with different levels of kidney function. It will enroll 28 adults, including both healthy participants and those with moderate to severe long-term kidney impai…

This early-stage study aims to see if two different versions of a migraine prevention drug are absorbed and processed the same way by the body. It involves 64 healthy adult volunteers who will each try both drug versions. The main goal is to gather data on how the body handles th…

This early-stage study aims to understand how a new medicine, PF-07328948, is processed in the bodies of people with different levels of liver impairment compared to healthy people. It will enroll 26 adults, some with stable liver disease and some without, who will take a single …

This study aims to understand the long-term heart health of young people under 21 who develop heart inflammation (myocarditis/pericarditis) after receiving the Pfizer COVID-19 vaccine or after a COVID-19 infection. Researchers will follow about 300 participants for up to 5 years,…

This study aims to observe how patients with moderate-to-severe atopic dermatitis (eczema) respond to the medication abrocitinib in real-world, everyday clinical practice. It will follow 200 patients aged 12 and older who are newly prescribed this medication by their doctor. Rese…

This study aims to monitor the safety of the Prevenar 20 pneumococcal vaccine in routine medical practice in Korea. It will enroll 660 participants aged 6 weeks and older who receive the vaccine as part of their normal healthcare. Researchers will track any side effects or reacti…

This is an early safety study for a potential new medicine called PF-07985631, which is being developed to treat a serious kidney disease called IgA nephropathy. The study will give single injections of the drug to healthy adult volunteers to check for side effects and see how th…

This study aims to understand if the migraine medication rimegepant is safe during pregnancy. It will follow pregnant women with migraines, some who take the drug and some who do not, to track the health of both mother and baby for up to a year after birth. The goal is to collect…

This study aims to understand if the eczema medication abrocitinib (CIBINQO) is safe for use during pregnancy. Researchers will follow 400 pregnant women with moderate-to-severe eczema—some taking the drug and some not—and track their babies' health through the first year of life…

This study aims to understand how two existing medications (itraconazole and probenecid) affect how the body processes a single dose of a new, experimental drug called PF-07220060. It involves 28 healthy adult volunteers who will take the new drug alone and then again while takin…

This study aims to understand how much of the medication etrasimod passes into breast milk when taken by breastfeeding women. Eight healthy women who are breastfeeding will take the drug daily for one week while staying at a research facility. Researchers will measure drug levels…

A study to learn about the long-term safety and efficacy of giroctocogene fitelparvovec or fidanacogene elaparvovec in patients with hemophilia A or hemophilia B respectively, who have received treatment through prior participation in a Pfizer-sponsored clinical trial. Data colle…