Pfizer

This study tested new pneumococcal vaccines in over 1,300 adults aged 18 and older to see if they are safe and help the body fight off pneumococcal disease. Participants received one shot of either a new vaccine or an existing one, and were monitored for side effects and immune r…

Pfizer completed a study testing a new modified RNA (mRNA) flu vaccine in 1,202 healthy adults aged 18 and older. The goal was to see if the vaccine is safe and triggers a strong immune response. Participants received either the experimental mRNA vaccine or a licensed flu shot, a…

This study tested a new vaccine (VLA15) to prevent Lyme disease, a tick-borne illness. About 12,500 healthy people aged 5 and older in high-risk areas received either the vaccine or a placebo. The goal was to see if the vaccine safely reduces Lyme disease cases compared to no vac…

This phase 3 trial tested a 13-valent pneumococcal vaccine (13vPnC) against the older 7-valent version in over 1,600 healthy infants in China. The goal was to see if the newer vaccine triggers a stronger immune response and is just as safe. Infants received four doses starting at…

This study tested a new vaccine called VLA15 to prevent Lyme disease, which is spread by tick bites. Researchers gave the vaccine or a placebo to 625 healthy people aged 5 to 65. The goal was to check safety and how well the vaccine triggers an immune response. Results showed the…

This study tested whether a new Lyme disease vaccine (VLA15) is safe for healthy children ages 5 to 17. Over 3,500 kids received either the vaccine or a placebo (saltwater shot) and were monitored for about 2 years. The main goal was to check for side effects like pain, redness, …

This Pfizer study tested a new 5-in-1 vaccine (MenABCWY) that targets five types of meningococcal bacteria, which can cause serious infections like meningitis. The trial involved 309 healthy teens aged 11 to 14 and compared two different dosing schedules (shots 12 months apart vs…

This completed study in Japan checked the safety of the RSV vaccine Abrysvo in 497 pregnant women and their infants. Researchers tracked side effects in mothers for 28 days after vaccination and in babies from birth to 28 days old. The goal was to confirm the vaccine's safety in …

Pfizer is testing a new type of flu vaccine called a self-amplifying RNA (saRNA) vaccine. This early study involves 440 healthy adults aged 18 to 49. Participants receive either the saRNA vaccine, a licensed flu shot, or a placebo. The main goal is to check safety and side effect…

This study tested a new pneumococcal vaccine in 225 healthy toddlers aged 12 to 15 months. The goal was to check safety and how well the vaccine triggers an immune response. Participants received either one or two doses and were monitored for side effects and antibody levels over…

This study tested a new mRNA vaccine designed to protect against a future flu pandemic. Healthy adults aged 18-49 and 65-84 received either the experimental vaccine, a licensed flu shot, or a placebo. Researchers monitored safety and immune responses for about 13 months to see if…

This study tested a new 20-valent pneumococcal vaccine (20vPnC) against an existing 13-valent vaccine in 400 adults aged 50 and older in China who had never received a pneumococcal vaccine. The goal was to check safety and immune response. Results will help decide if the broader-…

This study tested an RSV vaccine in 378 older adults (60+) in Korea to see if it is safe and helps the body fight the virus. Participants received either the vaccine or a placebo and were monitored for side effects and immune response. The results showed the vaccine was well tole…

This study tested a new vaccine (20vPnC) that protects against 20 types of pneumococcal bacteria, which can cause pneumonia and meningitis. Over 500 healthy infants in India and Taiwan received either the new vaccine or an existing one (13vPnC) as a series of four shots. Research…

This study tested whether giving the RSV vaccine (Abrysvo) and the shingles vaccine (Shingrix) at the same doctor's visit is safe and works as well as giving them separately. About 526 adults aged 50 and older took part. Researchers measured immune responses and tracked side effe…

This completed study looked at how effective the Prevnar 13 (PCV13) vaccine is at preventing pneumonia and related infections in adults with HIV. Researchers analyzed health records of over 350,000 people with HIV to compare those who got the vaccine with those who did not. The g…

This Pfizer trial tested whether a single injection combining an updated COVID-19 vaccine and a flu vaccine is safe and triggers a strong immune response. The study involved 644 healthy adults aged 50 and older. Researchers measured side effects and antibody levels to see if the …

This study tested an RSV vaccine in 453 healthy women aged 18-49. It compared a multidose vial with a preservative to a single-dose vial without one. The goal was to see if both versions are safe and produce a similar immune response. Participants received one shot and were follo…

This study looks at health records from about 99,000 adults in Ontario who had COVID-19 and visited a pharmacist. It compares those who got Paxlovid (nirmatrelvir-ritonavir) with those who didn't, to see if the drug lowers the chance of hospitalization, ICU admission, or death wi…

This study reviews medical records of 35 adults with a specific lung cancer (ROS1-positive NSCLC) that had not been controlled by other treatments. All participants took lorlatinib pills at home until their cancer stopped responding. Researchers will analyze how long the drug kep…

This study tested a drug called PF-06801591 in 155 people with advanced solid tumors or non-small-cell lung cancer. The drug works by blocking a protein that stops the immune system from attacking cancer cells. The goal was to check safety, how the drug moves through the body, an…

This early-stage trial tested a new drug called PF-07209326 in 52 people, first in healthy volunteers and then in patients with sickle cell disease. The main goal was to check safety and how the body processes the drug. Researchers also looked for any early signs that the drug mi…

This study tested a new once-weekly injection called MET097 in 133 adults with obesity or overweight and type 2 diabetes. The goal was to see if it helps with weight loss and blood sugar control compared to a placebo. Participants received either the drug or a placebo for 28 week…

This study tested the safety and effectiveness of Vizimpro (dacomitinib) in 40 Japanese patients with EGFR-mutated non-small cell lung cancer that could not be surgically removed or had returned. Researchers tracked side effects, especially interstitial lung disease, and measured…

This completed observational study looked at how well the drug tofacitinib works for people with ulcerative colitis in everyday Swedish clinics. Researchers used a national registry to track disease remission and whether patients stayed on the medication. The study included 102 p…

This early-stage trial tested a new drug called PF-07257876 in 29 people with advanced lung, head/neck, or ovarian cancers that had stopped responding to other treatments. The drug is a bispecific antibody designed to help the immune system attack cancer cells. The main goals wer…

This study tested a new drug called MET097, given as a weekly injection, to help adults with obesity or overweight lose weight. 239 participants received either MET097 or a placebo for 28 weeks. The main goal was to see how much weight people lost compared to those on placebo. Re…

This completed study looked at how patients with advanced EGFR-positive non-small cell lung cancer fared while taking dacomitinib in real-world settings in Taiwan. Researchers tracked 29 adults who took dacomitinib pills at home until their cancer stopped responding. The goal was…

This study tested the safety and effectiveness of the antifungal drug isavuconazole as a first treatment for Chinese patients with serious invasive fungal infections caused by Aspergillus or other molds. All 70 participants received the drug for up to 84 days (or 180 days for cer…

This early-stage trial tested a new weekly injection called MET233 in 144 otherwise healthy adults with overweight or obesity. The main goal was to check safety and how the drug moves through the body. Researchers also looked at different dosing schedules over several weeks. Sinc…

This completed phase 4 study tested whether rimegepant, a dissolvable tablet taken every other day, can prevent migraines in adults who did not get enough relief from other oral preventive medications. Over 960 participants were enrolled. The main goal was to see if rimegepant re…

This study looked at how safe and effective Vyndaqel is for people with a rare heart condition called transthyretin amyloid cardiomyopathy. Over 1,200 patients in Japan were followed while taking the drug in regular medical practice. The main goal was to track side effects and su…

This study tested whether adding palbociclib (a targeted cancer drug) to standard hormone therapy (letrozole) helps Asian postmenopausal women with a certain type of advanced breast cancer (ER+/HER2-). The trial involved 340 women who had not received prior treatment for their ad…

This study looked at medical records of 50 people with a rare heart condition called ATTR-CM to see if high-dose tafamidis (Vyndamax) slows nerve damage. Researchers compared how fast nerve problems got worse before and after starting the drug. The goal was to see if the medicati…

This completed study by Pfizer tested a biosimilar (a near-copy) of trastuzumab in 8 people with advanced or recurrent HER2-positive gastric cancer that could not be removed by surgery. The goal was to check safety and how well the drug worked in real-world use. Participants rece…

This study looked at how safe and effective the drug Cresemba (isavuconazole) is for Korean patients with serious fungal infections like invasive aspergillosis or mucormycosis. Researchers tracked side effects and how well the drug worked in 94 adults. The goal was to confirm the…

This study tested a drug called PF-06651600 in over 1,000 adults and teenagers with alopecia areata, a condition that causes patchy or complete hair loss. The goal was to see if the drug is safe and helps hair grow back over the long term. A smaller group also checked how well th…

This completed study examined the safety and effectiveness of Ibrance (palbociclib) in women with advanced or metastatic breast cancer using a large real-world database. Researchers looked at side effects and how well the drug worked in everyday practice. The study included adult…

This study tested a combination of two targeted drugs, encorafenib and binimetinib, in 98 people with advanced non-small cell lung cancer that has a specific BRAF gene mutation. The goal was to see if the drugs could shrink tumors and how safe they were. Participants had either n…

This study followed 302 children with juvenile idiopathic arthritis (JIA) who had previously taken tofacitinib in earlier studies. The goal was to see how safe the drug is over the long term, by tracking side effects, lab results, and growth. Children took tofacitinib twice daily…

This study looked at how well the drug lorlatinib works for people with advanced non-small cell lung cancer that has a specific gene change (ALK). All 73 participants had already tried other treatments and took lorlatinib pills at home. The study tracked how long the drug kept th…

This phase 3 trial tested a combination of two targeted drugs, LGX818 and MEK162, against standard treatments in 921 people with advanced melanoma that has a BRAF V600 mutation. The study compared the combo to vemurafenib alone or LGX818 alone to see which worked better at delayi…

This Phase 3 study tested ritlecitinib, an oral drug, in 607 adults and adolescents with nonsegmental vitiligo (a type of white patches on the skin). Participants took either the drug or a placebo daily for 52 weeks. The main goals were to see if the drug could improve skin color…

This early-stage study tested the drug palbociclib (combined with letrozole) in 26 postmenopausal Chinese women with a specific type of advanced breast cancer (ER+, HER2-). The main goal was to see how the drug moves through the body and to check for safety. The study is complete…

This study tested a new way of giving the drug elranatamab to people with multiple myeloma that came back or didn't respond to treatment. The drug was given as a shot under the skin, starting with low doses and then increasing, with longer breaks between doses over time. The goal…

This study tested a new daily pill called PF-07976016 in 263 adults with obesity. Participants received either the active drug or a placebo for several weeks. Researchers measured weight changes and tracked any side effects to see if the drug is safe and helps with weight loss.

This study tested a drug called enzalutamide in 1401 men with a type of prostate cancer that has not spread to other parts of the body but is no longer controlled by standard hormone therapy. The goal was to see if enzalutamide could delay the cancer from spreading. Participants …

This study tested the safety and effectiveness of abrocitinib, a daily pill, for people aged 12 and older with moderate to severe eczema. Participants took either 100 mg or 200 mg of abrocitinib for up to 92 weeks, with some continuing until the drug became commercially available…

This study tested whether the drug rimegepant can help prevent migraines in Chinese adults. 787 participants took either rimegepant or a placebo every other day for 12 weeks. The main goal was to see if rimegepant reduced the number of migraine days per month compared to placebo.…

This completed Phase 3 study tested somatropin, a synthetic growth hormone, in 33 Japanese children and adults with Prader-Willi syndrome. The goal was to see if it safely improves body composition by increasing lean body mass and reducing fat. Participants were divided into thre…

This study followed 152 adults with moderate to severe ulcerative colitis who were prescribed tofacitinib by their doctors in France. Researchers tracked how many patients felt better after one and two years of treatment, using symptom scores and noting if they needed other medic…

This study tested a drug called elranatamab in 39 Chinese patients with multiple myeloma that had stopped responding to at least three prior treatments. The drug works by helping the immune system attack cancer cells. The goal was to see if it could shrink tumors and control the …

This study tested a biosimilar version of the drug infliximab (made by Pfizer) in 77 people with rheumatoid arthritis. The goal was to see how safe and effective it is in real-world use. Participants received the drug by IV infusion, and researchers tracked side effects and disea…

This completed study monitored the safety and effectiveness of BESPONSA (inotuzumab ozogamicin) in 108 Korean adults with relapsed or refractory B-cell acute lymphoblastic leukemia (ALL). The drug is already approved in Korea, and this post-marketing surveillance was required to …

This study looked at over 9,000 people with rheumatoid arthritis to compare how well different treatments work in everyday medical practice. Researchers compared drugs like TNF inhibitors and tofacitinib, given alone or with methotrexate, to see which combination controls disease…

This completed Phase 4 trial tested the drug rimegepant as a preventive treatment for people with episodic migraines (4–14 migraine days per month). Over 1,400 participants were randomly assigned to take rimegepant daily, every other day, or a placebo for 12 weeks. The main goal …

This study looked at the safety of the drug BESPONSA in 421 people with a type of blood cancer called acute lymphocytic leukemia that had come back or stopped responding to treatment. All participants received BESPONSA as prescribed by their doctor. Researchers tracked side effec…

This study tested a drug called inotuzumab ozogamicin in 44 Chinese adults whose acute lymphoblastic leukemia (ALL) had come back or stopped responding to treatment. The drug targets a protein called CD22 on leukemia cells to destroy them. The main goal was to see how many patien…

This study tested a drug called inclacumab in about 240 people with sickle cell disease who experience painful vaso-occlusive crises. Participants received either inclacumab or a placebo by IV infusion. The main goal was to see if inclacumab could reduce the number of these painf…

This study looked at how well the drug tafamidis 61mg works for Korean patients with a rare heart condition called transthyretin amyloid cardiomyopathy (ATTR-CM). Researchers tracked 13 patients who were already prescribed the drug in real-world clinics. They measured changes in …

This study looked at the safety of a drug called Tafamidis (brand name VyndaMx) in 6 people in India with a rare heart condition called transthyretin amyloid cardiomyopathy (ATTR-CM). In ATTR-CM, faulty proteins build up in the heart and make it harder to pump blood. Researchers …

This study tested whether the drug rimegepant, taken as a dissolving tablet every other day, could prevent migraines in Japanese adults. About 496 people with a history of migraines participated. The main goal was to see if rimegepant reduced the number of migraine days per month…

This Phase 2 study tested the drug lorlatinib in 109 people in China with advanced ALK-positive non-small cell lung cancer whose disease had progressed after treatment with other ALK inhibitors. The goal was to see how many patients' tumors shrank or disappeared. The trial is now…

This study looked at how well the drug tofacitinib works for people with psoriatic arthritis in everyday medical practice. Over 12 months, researchers tracked 116 adults to see if the drug reduced disease activity and improved quality of life. The goal was to understand real-worl…

This phase 2 trial tested whether adding the experimental drug PF-07220060 to the standard hormone therapy letrozole works better than letrozole alone in postmenopausal women with a common type of breast cancer (HR+/HER2-). The 121 participants took the pills for 14 days before t…

This study tested a new gene therapy (SB-525) in 13 adults with severe hemophilia A, a bleeding disorder. The goal was to see if a single infusion could safely raise the body's own clotting factor levels and reduce bleeding episodes. Participants were monitored for up to 5 years …

This completed study looked at side effects of the lung cancer drug Lorbrena in 1,290 patients. Researchers focused on nervous system problems and liver damage. The goal was to understand what factors might increase these risks during real-world use.

This Phase 2 trial tested whether adding enzalutamide (a drug that blocks male hormones) to the standard hormone therapy exemestane could help slow advanced breast cancer in postmenopausal women. The study enrolled 247 participants with hormone receptor-positive, HER2-normal brea…

This study tested the safety of taking rimegepant every day to prevent episodic migraines. 441 adults with a history of migraines took a daily 75mg tablet for up to 52 weeks. Researchers tracked side effects and lab changes to see if long-term daily use is safe and tolerable.

This study tested an investigational drug called ponsegromab in 187 adults with lung, pancreatic, or colorectal cancer who also had cachexia—a condition causing severe weight loss, loss of appetite, and fatigue. The goal was to see if ponsegromab could help patients gain weight a…

This study tested whether a nasal spray called zavegepant can safely and effectively treat migraine attacks in Asian adults. Over 1,400 participants took either the drug or a placebo when they had a moderate or severe migraine. The main goals were to see if the spray could stop p…

This study tested whether rimegepant, a dissolvable tablet, can relieve migraine pain in adults who cannot take triptans due to side effects, lack of effectiveness, or heart problems. Over 800 participants took either rimegepant or a placebo during a migraine attack. The main goa…

Pfizer completed a Phase 1 study testing a new topical drug called PF-07905428 for acne. The study included 52 healthy volunteers and people with moderate to severe acne, who applied the drug daily for 14 or 28 days. The main goal was to check safety and side effects, not to see …

This study looks at whether breast cancer patients with mild, moderate, or severe liver problems face a higher risk of a serious side effect—grade 4 neutropenia (a dangerous drop in infection-fighting white blood cells)—when taking the drug palbociclib. Researchers analyzed medic…

This study looks at medical records from France to see how doctors prescribe blood thinners to people with atrial fibrillation (an irregular heartbeat) who also have a high risk of stomach bleeding. The goal is to understand which treatments are used and how often serious bleedin…

This study looks at medical records from across Europe to see how well a drug combination (palbociclib plus an aromatase inhibitor) works as a first treatment for people with a common type of advanced breast cancer (HR+/HER2-). Researchers want to understand how long the treatmen…

This study looks at anonymous health records from California and Louisiana to see if the Pfizer-BioNTech COVID-19 vaccine helps prevent post-COVID conditions (long COVID). Researchers will also track who gets vaccinated. The study includes adults with a COVID-19 diagnosis between…

This study follows adults with migraine who have been prescribed rimegepant (a dissolving tablet) for acute attacks. Researchers want to see how consistently the drug provides meaningful pain relief across multiple attacks and how satisfied people are with it. The study also look…

This study looks back at medical records from a single hospital in Scotland to see how well the drug bosutinib works and how safe it is for people with chronic myeloid leukemia (CML) in everyday practice. Researchers will track blood cell counts, genetic responses, and side effec…

This study used health records from over 8 million people in Taiwan to understand the effects of COVID-19 and how well the oral treatment nirmatrelvir/ritonavir works. Researchers looked at who got severely ill, needed hospital care, or died, and compared those who took the treat…

This study reviewed medical records of 494 adults with advanced kidney cancer who received immunotherapy as their first treatment. Researchers looked at how long patients stayed on treatment, how they responded, and survival rates. The goal was to understand which treatment combi…

This study tested an electronic diary for adults with sickle cell disease to track daily symptoms like pain, tiredness, and ability to do usual activities. About 98 participants used the diary for 6 months, and researchers compared those on disease-modifying treatment to those no…

This study looked at 185 people with a common type of advanced breast cancer (HR+/HER2-) in Africa and the Middle East who were starting treatment with palbociclib combined with hormone therapy. Researchers tracked how long the cancer stayed under control and how patients felt ov…

This study analyzed data from a database to understand how adults with severe alopecia areata and their doctors experienced treatment with ritlecitinib compared to older treatments. Researchers looked at patient characteristics, treatment history, and doctor satisfaction. The goa…

This completed Phase 1 study tested how the antifungal drug fluconazole changes the way the body processes an experimental drug called PF-07248144. Twelve healthy adults took PF-07248144 alone and then again with fluconazole. Researchers measured drug levels in the blood to under…

This study looked at how well two different tablet versions of an experimental drug (PF-07220060) enter the bloodstream. It also tested whether taking the drug with food or with a stomach acid medication (rabeprazole) changes absorption. About 113 healthy adults aged 18–65 took p…

This study looked at the safety of Bevacizumab-Pfizer Biosimilar, a drug used to treat colorectal cancer, by analyzing medical records from 1,000 patients in Japan. Researchers focused on side effects like bleeding, high blood pressure, and kidney problems. The goal was to unders…

This completed study looked at medical records of over 1,100 people in Australia who took CDK4/6 inhibitors (like palbociclib) for advanced or metastatic breast cancer. Researchers wanted to understand patient characteristics, dosing, and how long people stayed on treatment in re…

This completed study looked at 121 women in Brazil with a certain type of advanced breast cancer (HR+/HER2-). Researchers tracked how doctors prescribed palbociclib combined with other drugs in everyday practice, not in a strict trial setting. The goal was to describe patient bac…

This study looked at how healthy adults absorb, break down, and eliminate the experimental drug ARV-471. Twelve participants each took a single radioactive dose of the drug. Researchers measured levels in blood, urine, and stool to understand the drug's path through the body. Thi…

This study looked at medical records from over 1,300 breast cancer patients in Japan who took the drug palbociclib. The goal was to find out which patients are more likely to develop a severe drop in white blood cells (grade 4 neutropenia), a known side effect. Researchers compar…

This completed study looked at medical records of 258 adults in Saudi Arabia, UAE, and other Gulf countries who received palbociclib (a targeted cancer pill) combined with hormone therapy for advanced HR+/HER2- breast cancer. Researchers aimed to describe patient characteristics,…

This study looks at how adults with advanced bladder cancer are treated in everyday medical practice, not in a controlled trial. Researchers will analyze data from cancer clinics to see how long patients go without their disease worsening after starting their first treatment. The…

This study looked at medical records from over 2,700 people in Japan with a type of lymphoma (B-cell non-Hodgkin's lymphoma) who were treated with Rituximab Pfizer. The goal was to see how often infections and other side effects happened, and to compare these results with those f…

This study checks whether prazosin capsules made in Barceloneta (Puerto Rico) and Ascoli (Italy) are absorbed and processed the same way in the body. About 69 healthy adults will take the capsules and give blood samples. The goal is to confirm the manufacturing site change does n…

This study tested four different formulations of a CGRP receptor antagonist, a drug used for migraines, in 64 healthy adults. The goal was to see if the different versions are absorbed and processed by the body in the same way. This is a Phase 1 trial, so it focuses on safety and…

This completed Phase 1 study looked at how much of the COVID-19 treatment nirmatrelvir/ritonavir (Paxlovid) gets into breast milk. Eight healthy breastfeeding women took the drug by mouth three times over two days. Researchers collected breast milk samples to measure drug levels,…

This study looked at how a new medicine, PF-07328948, is handled by the body and whether it is safe in healthy Chinese adults. Ten participants took the drug daily for a week. The goal was to gather early safety and drug-level information to support future heart failure treatment…

This completed study analyzed medical records of 1,170 advanced breast cancer patients in Japan to see how they used the drug palbociclib (Ibrance). Researchers looked at blood test frequency and how long patients stayed on treatment. The goal was to describe real-world treatment…

This completed Phase 1 study tested whether a new, higher-dose tablet of the cancer drug atirmociclib works the same in the body as the current tablet. Thirty-five healthy adults each received a single dose of both tablet forms after a meal, in random order. The goal was to see i…

This study looked back at medical records of 693 Japanese patients with a certain type of advanced breast cancer (HR+/HER2-) who received palbociclib plus endocrine therapy as their first or second treatment. Researchers measured how long patients lived without the cancer getting…

This early-stage study tested a new oral drug called PF-07940369 in 30 healthy adults to see if it is safe and how the body processes it. Participants took the drug or a placebo once or twice daily for 14 days while staying at a clinic. The main goal was to check for side effects…

This study looked at how two common drugs (itraconazole and probenecid) change the way the body handles a new experimental medicine called PF-07220060. It involved 25 healthy adults who took the new medicine alone and then again with the other drugs. The goal was to understand po…

This study observed 440 adults in Poland with advanced HR+ HER2- breast cancer to understand how doctors treat the disease in everyday practice. Researchers tracked treatment choices, changes over one year, and how they relate to patient characteristics and guidelines. The goal w…

This completed study tracked 596 patients in France with advanced bladder cancer who received avelumab as maintenance therapy after initial chemotherapy. Researchers observed how long patients survived and how the drug performed in everyday medical practice, rather than in a cont…

This study looked at how the drug carbamazepine changes the way the body handles another drug called PF-07248144. Twelve healthy adults took PF-07248144 alone and then with carbamazepine. Researchers measured drug levels in the blood to understand the interaction and check for sa…

This completed Phase 1 study looked at how healthy men absorb, process, and eliminate the experimental drug PF-07220060. Twelve participants received the drug by mouth or by injection. Researchers measured the drug and its breakdown products in blood, urine, and stool to understa…

This study reviewed medical records of women with advanced or metastatic HR+/HER2- breast cancer who received Palbociclib combined with hormone therapy in community clinics. The goal was to see how doctors actually prescribe these drugs, how long patients stay on treatment, and w…

This study looked at how patients with advanced kidney cancer fared when taking the drug axitinib after first trying sunitinib. Researchers did not give any new treatment—they simply observed 554 patients to see how long the drug worked and how long patients stayed on it. The goa…

This study looked at medical records from over 2,700 men with advanced prostate cancer that no longer responds to hormone therapy. Researchers compared two common treatments, enzalutamide and abiraterone, to see which one helped men live longer. The goal was to understand how the…

This study used a tiny radioactive tag to track how the experimental drug PF-07248144 moves through the body. Eight healthy adults took the drug by mouth and later by IV to measure absorption and elimination. The goal was to understand the drug's behavior, not to treat any diseas…

This study looked at the safety and effectiveness of the drug Vizimpro in 188 adults with advanced lung cancer who had specific gene mutations. It was an observational study, meaning patients received their normal treatment and researchers simply collected data on side effects an…

This completed study looked at over 131,000 high-risk COVID-19 patients in the US to understand how the illness affected their ability to work and the associated costs. Researchers compared those who took the antiviral Paxlovid with those who did not, using insurance claims data …

This completed Phase 1 study looked at how two common drugs—cyclosporine and clarithromycin—affect the levels of a new experimental medicine called PF-07328948 in the body. Twenty-six healthy adults received PF-07328948 alone and then with cyclosporine or clarithromycin. The goal…

This study tested whether a small device that collects blood from the arm (instead of a needle in the vein) works as well for measuring levels of the drug zavegepant. Fourteen healthy adults took the nasal spray and gave blood samples using both methods. The goal was to see if th…

This completed study looked at over 1,000 men with metastatic prostate cancer in the Pirkanmaa region of Finland. Researchers analyzed patient characteristics, treatments used, and outcomes to better understand the disease burden. The goal was to fill gaps in knowledge about how …

This completed study looked at survey responses from over 1,300 people with migraine in the U.S. to compare those taking rimegepant (Nurtec) with those taking triptans. Researchers examined treatment satisfaction, quality of life, work productivity, and disability. The goal was t…

This study looked at medical records of 86 people with HER2+ metastatic breast cancer to see how well a combination of tucatinib, trastuzumab, and capecitabine worked after they had already received a treatment called T-DXd. The goal was to measure things like time until the next…

This early-stage study looked at how the drug Ibuzatrelvir (PF-07817883) is absorbed and processed in the body of 12 healthy Chinese adults after a single dose. The goal was to measure drug levels in the blood and check for any side effects. Since participants were healthy, this …

This completed study examined how long men with metastatic castration-sensitive prostate cancer take newer hormonal therapies like abiraterone, apalutamide, and enzalutamide. Researchers analyzed Medicare claims data from over 3,000 men aged 65 and older. The goal was to describe…

This completed study analyzed data from over 2 million people in France with atrial fibrillation (an irregular heart rhythm) to compare outcomes between those who took blood thinners and those who did not. Researchers looked at rates of stroke, major bleeding, and death between 2…

This completed Phase 1 study by Pfizer enrolled 9 healthy adult men to learn how the experimental drug PF-07104091 is absorbed, broken down, and eliminated. Participants took the drug by mouth and later received a tiny radioactive dose intravenously. The study measured how much o…

This completed study looked at 559 adults in Israel with metastatic breast cancer who were prescribed palbociclib (Ibrance) as part of their treatment. Researchers tracked how the drug was used in everyday practice, including doses, combinations with other treatments, and how lon…

This study analyzed medical records of 507 U.S. veterans with prostate cancer who started taking the drug relugolix between 2020 and 2023. Researchers wanted to understand the patients' backgrounds, previous treatments, and health conditions. The study did not test a new treatmen…

This completed study looked at medical records of 307 adults in five European countries who were treated with the antifungal drug isavuconazole for serious fungal infections (invasive aspergillosis or mucormycosis). Researchers tracked how well the drug worked (clinical, radiolog…

This Pfizer study tested whether wearable activity monitors (like a smartwatch) can accurately measure walking, running, and sleep in healthy children aged 3 to 17. Eighty-seven kids wore the devices during lab activities and at home for two weeks. The goal was to see if these to…

This completed study in Japan reviewed medical records of 42 patients with HR+/HER2- advanced breast cancer who had been treated with palbociclib plus letrozole. The goal was to see how long patients lived after starting this treatment. It was a follow-up to an earlier phase 2 st…

This study reviewed medical records from over 1,300 men with metastatic prostate cancer that still responds to hormone therapy. Researchers wanted to see how long patients actually take the pills apalutamide or enzalutamide when prescribed by their own doctors in routine care. Th…

This early-stage study in 10 healthy men aims to understand how the experimental drug PF-07054894 is absorbed, broken down, and eliminated from the body. Participants receive a single dose with a tiny radioactive label to track the drug's path. The results will help guide future …

This completed Phase 1 study by Pfizer enrolled 24 healthy adults to compare how two different tablet forms of the drug PF-07248144 are absorbed by the body. Participants received single doses of each form in a crossover design, with some taking the drug after eating. The goal wa…

This completed study looked at how safe and effective the drug IBRANCE® is for women with advanced breast cancer when used in everyday medical practice. Researchers tracked 552 women in Korea for side effects and how well the drug worked. The goal was to gather real-world informa…

This completed study looked at how the drug carbamazepine changes the way the body handles a new medicine called PF-07220060. Fourteen healthy adults took PF-07220060 alone and then again after taking carbamazepine for several days. Blood samples were collected to measure drug le…

This study looked at over 12,500 people in Korea with atrial fibrillation (an irregular heartbeat) to see how their condition and health outcomes changed over time. Researchers used existing hospital and national insurance records, not new patient visits. The goal was to better u…

This study looked at medical records of 779 older adults (65+) with a certain type of advanced breast cancer (HR+/HER2-). It compared survival in those who received a combination of the drug palbociclib plus hormone therapy versus hormone therapy alone. The goal was to see which …

This study looked at how an experimental medicine called PF-08049820 moves through the body when taken in different forms (fast-release and slow-release tablets) and with or without food. Twelve healthy adults each tried five versions of the medicine, with blood samples taken for…

This study gathered information on how often adults with moderate to severe hemophilia A or B experience bleeding while on their usual treatment. The data will be used as a baseline for future gene therapy studies. About 212 participants took part, and no experimental treatment w…

This completed Phase 1 study gave a single IV dose of the antiviral PF-07304814 to 5 healthy adults. Researchers measured how much of the drug ended up in urine and feces, and how it was processed in the blood. The goal was simply to understand the drug's breakdown and eliminatio…

This study looked at medical costs for cancer patients who had a blood clot (VTE) and were treated with either apixaban or low molecular weight heparin. Researchers analyzed insurance claims from over 7,300 patients to compare total healthcare costs, including hospital stays and …

This early-stage study tested the safety and how the body handles a new drug called PF-06414300 in 63 healthy adults. Participants received either the drug or a placebo in single or multiple doses. The study is complete and focused on measuring side effects and drug levels in the…

This study tested a new medicine called PF-07264660 in 12 healthy Chinese adults to see if it is safe and how the body processes it. Participants received a single IV dose, with three-quarters getting the real medicine and one-quarter getting a placebo. The study lasted up to 181…

This early-stage study tested two different pill versions of an experimental drug called PF-07976016 in 12 healthy adults. The main goal was to measure how much of the drug gets into the blood and how the body processes it. This type of study helps researchers choose the best for…

This completed Phase 1 study looked at how the experimental drug PF-07976016 is absorbed, distributed, and removed from the body. Eight healthy male volunteers took the drug by mouth and by vein so researchers could track its path using a tiny radioactive marker. The goal was pur…

This study looked at data from nearly 20 million people in California and Louisiana to see how well different versions of Pfizer's COVID-19 vaccine prevented severe illness, hospitalization, and death. Instead of enrolling new volunteers, researchers used existing health records …

This completed study from Pfizer looked at the safety and effects of the COVID-19 medicine PAXLOVID in over 3,300 people aged 12 and older. All participants took PAXLOVID twice a day for five days and were monitored for 28 days. The main goal was to track any side effects, includ…