Gulf study reveals Real-World use of palbociclib for advanced breast cancer

NCT ID NCT04916509

Completed Knowledge-focused Sponsor: Pfizer Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This completed study looked at medical records of 258 adults in Saudi Arabia, UAE, and other Gulf countries who received palbociclib (a targeted cancer pill) combined with hormone therapy for advanced HR+/HER2- breast cancer. Researchers aimed to describe patient characteristics, treatment patterns, and outcomes like how long the cancer was controlled. Since this is a retrospective study, it does not test a new treatment but provides real-world insights into how palbociclib is used in this region.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Palbociclib (a targeted cancer drug) combined with either an aromatase inhibitor or fulvestrant
What this could lead to: If successful, this study could help doctors in the Gulf region better understand how palbociclib is used in real-world practice and what outcomes patients experience.
What could go wrong: This is a retrospective study that only looks back at existing data, so it cannot prove cause and effect. Results may not apply to other regions or newer treatment approaches.

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Conditions

The condition(s) this trial relates to.

breast neoplasm hormone receptor-positive breast cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST NEOPLASMS

Contacts and locations

Locations

Dubai Hospital

Dubai, United Arab Emirates
Hamad Medical Corporation

Doha, Qatar
King Abdulaziz Medical City National Guard Hospital

Jeddah, 22384, Saudi Arabia
King Abdulaziz Medical City National Guard Hospital Riyahd

Riyadh, 11426, Saudi Arabia
King Saud University Medical City Riyadh PO BOX 7805

Riyadh, 11472, Saudi Arabia
Mediclinic City Hospital

Dubai, United Arab Emirates
Tawam

Al Ain City, United Arab Emirates

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