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Real-World study checks how well tofacitinib controls ulcerative colitis

NCT ID NCT04338204

Completed Disease control Sponsor: Pfizer Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed observational study looked at how well the drug tofacitinib works for people with ulcerative colitis in everyday Swedish clinics. Researchers used a national registry to track disease remission and whether patients stayed on the medication. The study included 102 patients and focused on real-world effectiveness rather than a controlled experiment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
tofacitinib
What this could lead to
If successful, this study could confirm that tofacitinib works well in everyday clinical practice for ulcerative colitis patients, supporting its continued use.
What could go wrong
This is an observational study, not a controlled trial, so results may be influenced by patient selection and real-world factors. It does not prove long-term safety or superiority over other treatments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

ulcerative colitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ULCERATIVE COLITIS

Contacts and locations

Locations

  • Danderyds Hospital

    Stockholm, 18257, Sweden

  • Daniel Molin

    Kristianstad, 29185, Sweden

  • Ersta Sjukhus, Medicinkliniken, Fjällgatan 44

    Stockholm, 11691, Sweden

  • Gävle Hospital

    Gävle, 80324, Sweden

  • Karolinska Universitetssjukhuset i Solna, Eugeniavägen 3, B4-09,

    Stockholm, 17176, Sweden

  • Mag-Tarmmedicinska kliniken, Universitetssjukhuset i Linköping

    Linköping, 58185, Sweden

  • Medicinkliniken, Länssjukhuset Ryhov, Sjukhusgatan

    Jönköping, 55185, Sweden

  • Medicinkliniken, Södra Älvsborgs Sjukhus Borås, Brämhultsvägen 53

    Borås, Sweden

  • Medicinkliniken, Umeås Universitetssjukhus

    Umeå, 50985, Sweden

  • Medicinmottagning 4, Medicinska Kliniken, Universitetssjukhuset Örebro

    Örebro, 70185, Sweden

  • Medicinmottagningen gastroenterologi, Västmanlands sjukhus

    Västerås, 72189, Sweden

  • Region skåne, Skånes Universitetssjukhus

    Malmö, 20501, Sweden

  • SU/Sahlgrenska, Gastroenterologi & Hepatologi

    Gothenburg, Göteborg, Sweden

  • Shiprock Consulting AB,

    Lidingö, Sweden

  • Specialmedicin, Akademiska Sjukhuset, Sjukhusvägen ing 40

    Uppsala, 75185, Sweden

  • Stockholm Gastro Center

    Stockholm, 11486, Sweden

  • Ulf Eriksson

    Alingsås, SE-441 33, Sweden

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