Daily pill could keep migraines at bay
NCT ID NCT05207865
First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tested the safety of taking rimegepant every day to prevent episodic migraines. 441 adults with a history of migraines took a daily 75mg tablet for up to 52 weeks. Researchers tracked side effects and lab changes to see if long-term daily use is safe and tolerable.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
rimegepant (a daily pill for migraine prevention)
What this could lead to
If successful, this could confirm that taking rimegepant daily is a safe option to prevent migraines, reducing attack frequency.
What could go wrong
This is a completed Phase 4 safety study, not designed to prove how well it works. Side effects or lack of long-term benefit may limit use.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Advanced Investigative Medicine, Inc.
Hawthorne, California, 90250, United States
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Boston Clinical Trials
Boston, Massachusetts, 02131, United States
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CVS HealthHUB - Runnemede
Runnemede, New Jersey, 08078, United States
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CVS HealthHub - East Brunswick
East Brunswick, New Jersey, 08816, United States
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CVS HealthHub - Lawrenceville
Lawrenceville, New Jersey, 08648, United States
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Chase Medical Research, LLC
Waterbury, Connecticut, 06708, United States
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Clinical Research Philadelphia, LLC
Philadelphia, Pennsylvania, 19114, United States
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Elite Clinical Studies, LLC
Phoenix, Arizona, 85018, United States
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Michigan Head Pain & Neurological Institute
Ann Arbor, Michigan, 48104, United States
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OK Clinical Research, LLC
Edmond, Oklahoma, 73034, United States
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Phoenix Medical Research, LLC
Miami, Florida, 33165, United States
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SPRI Clinical Trials, LLC
Brooklyn, New York, 11235, United States
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The Headache Clinic
Alexandria, Louisiana, 71301, United States
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Tidewater Integrated Medical Research
Virginia Beach, Virginia, 23454, United States
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VIP Trails
San Antonio, Texas, 78230, United States
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VIP Trials
San Antonio, Texas, 78230, United States
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Velocity Clinical Research
Cincinnati, Ohio, 45242, United States
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Velocity Clinical Research - North Hollywood
North Hollywood, California, 91606, United States
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WR-ClinSearch, LLC
Chattanooga, Tennessee, 37421, United States