New drug combo tested for advanced breast cancer in chinese women

NCT ID NCT02499146

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage study tested the drug palbociclib (combined with letrozole) in 26 postmenopausal Chinese women with a specific type of advanced breast cancer (ER+, HER2-). The main goal was to see how the drug moves through the body and to check for safety. The study is complete, and results help guide future use in this population.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Palbociclib (a targeted cancer drug) and Letrozole (a hormone therapy)

What this could lead to

If successful, this study could help confirm that palbociclib works similarly in Chinese patients, supporting its use as a treatment for advanced breast cancer in this population.

What could go wrong

This is a very early (Phase 1) study with only 26 participants, focused on drug levels in the body, not on curing cancer. Side effects are possible, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer hormone receptor-positive breast cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Beijing Cancer Hospital/Oncology department

    Beijing, Beijing Municipality, 100142, China

  • Cancer Institute and Hospital, Chinese Academy of Medical Sciences

    Beijing, 100021, China

  • Guangdong General Hospital/Department of Breast Surgery

    Guangzhou, Guangdong, 510080, China

  • Harbin Medical University Cancer Hospital

    Harbin, Heilongjiang, 150081, China

  • Sun Yat-Sen University Cancer Center

    Guangzhou, Guangdong, 510060, China

  • The First Affiliated Hospital of College of Medicine, Zhejiang University

    Hangzhou, Zhejiang, 310003, China

  • The first hospital of jilin university

    Changchun, Jilin, 130021, China