Could a pill replace an IV for advanced breast cancer treatment?

NCT ID NCT07684456

First seen Jul 06, 2026 · Last updated Jul 07, 2026 · Updated 1 time

Summary

This Phase 3 trial compares two forms of the chemotherapy drug utidelone—a capsule taken by mouth versus an injection—both combined with another chemo drug, capecitabine, in people with HER-2 negative advanced breast cancer. The study aims to see if the oral capsule works as well as the injection at delaying cancer growth. About 308 participants with advanced or metastatic breast cancer are being enrolled.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Utidelone (a chemotherapy drug) given as a capsule or injection, combined with capecitabine
What this could lead to
If successful, this could provide a more convenient oral option for treating advanced breast cancer, potentially improving quality of life while controlling the disease.
What could go wrong
This is a Phase 3 trial, but results may not show a significant benefit over existing treatments. Side effects from chemotherapy, such as nausea, fatigue, and nerve damage, are possible.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cancer Hospital Chinese Academy of Medical Sciences

    Beijing, China

    Contact

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