New 20-Strain pneumonia vaccine shows promise for infants

NCT ID NCT05512819

Completed ⭐️ VACCINE ⭐️ Sponsor: Pfizer Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new vaccine (20vPnC) that protects against 20 types of pneumococcal bacteria, which can cause pneumonia and meningitis. Over 500 healthy infants in India and Taiwan received either the new vaccine or an existing one (13vPnC) as a series of four shots. Researchers monitored safety and immune responses for about 15 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: 20-valent pneumococcal conjugate vaccine
What this could lead to: If successful, this vaccine could protect infants against 20 types of pneumococcal bacteria, reducing serious illnesses like pneumonia and meningitis.
What could go wrong: This is a completed Phase 3 trial, but results are not yet published. The vaccine may cause side effects like fever or swelling, and its long-term effectiveness is still being studied.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

pneumococcal infection prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PNEUMOCOCCAL DISEASE

Contacts and locations

Locations

BGS Global Institute of Medical Sciences (BGSGIMS)

Bangalore, Karnataka, 560060, India
Bharati Vidyapeeth {Deemed to be University) Medical College Hospital & Research Centre

Pune, Maharashtra, 411043, India
Chang Gung Medical Foundation-Linkou Branch

Taoyuan, 333, Taiwan
Hsinchu Mackay Memorial Hospital

Hsinchu, Hsinchu, 30071, Taiwan
Institute of Child Health

Kolkata, West Bengal, 700017, India
Jawahar Lal Nehru Medical College

Ajmer, Rajasthan, 305001, India
Mackay Memorial Hospital

Taipei, 10449, Taiwan
Maulana Azad Medical College and Associated with Lok Nayak Hospital

New Delhi, National Capital Territory of Delhi, 110002, India
National Taiwan University Hospital

Taipei, 10002, Taiwan
Nirmal Hospital Pvt Ltd.

Surat, Gujarat, 395002, India
Taichung Veterans General Hospital

Taichung, 407219, Taiwan

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