Can a pneumonia vaccine protect the most vulnerable children?

NCT ID NCT06817421

Not yet recruiting ⭐️ VACCINE ⭐️ Sponsor: Nick Fancourt Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a pneumococcal vaccine (Pneumosil) can produce a strong immune response in children aged 6-59 months who are hospitalised with severe acute malnutrition. Half the children will receive the pneumococcal vaccine, and the other half will receive a typhoid vaccine as a control. Researchers will measure antibody levels over six months to see if the vaccine works well in these malnourished children.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Pneumococcal conjugate vaccine (Pneumosil)

What this could lead to

If successful, this could show that giving pneumococcal vaccine to severely malnourished children helps protect them against pneumonia and other infections.

What could go wrong

This is a single-centre trial with only 214 children, so results may not apply everywhere. The immune response in malnourished children may be weaker than expected.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

pneumonia protein-energy malnutrition pneumococcal infection prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Guido Valadares National Hospital (HNGV)

    Dili, Timor-Leste, Timor-Leste