Can a pneumonia vaccine protect the most vulnerable children?
NCT ID NCT06817421
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a pneumococcal vaccine (Pneumosil) can produce a strong immune response in children aged 6-59 months who are hospitalised with severe acute malnutrition. Half the children will receive the pneumococcal vaccine, and the other half will receive a typhoid vaccine as a control. Researchers will measure antibody levels over six months to see if the vaccine works well in these malnourished children.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Pneumococcal conjugate vaccine (Pneumosil)
- What this could lead to
- If successful, this could show that giving pneumococcal vaccine to severely malnourished children helps protect them against pneumonia and other infections.
- What could go wrong
- This is a single-centre trial with only 214 children, so results may not apply everywhere. The immune response in malnourished children may be weaker than expected.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Guido Valadares National Hospital (HNGV)
Dili, Timor-Leste, Timor-Leste
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- New scoring system aims to cut child deaths from malnutrition in chad