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New hope for tough lung cancers: lorlatinib shows promise in Real-World study

NCT ID NCT06282991

Completed Disease control Sponsor: Pfizer Source: ClinicalTrials.gov ↗

First seen Mar 16, 2026 · Last updated May 19, 2026 · Updated 6 times

Summary

This study looked at how well the drug lorlatinib works for people with advanced non-small cell lung cancer that has a specific gene change (ALK) and has stopped responding to earlier treatments. Researchers tracked 73 adults in Taiwan who took lorlatinib pills at home. The goal was to see how long the drug controlled the cancer and what side effects occurred. The study found that lorlatinib helped some patients, but side effects like high cholesterol, swelling, and rash were common.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CHANG GUNG MEMORIAL HOSPITAL Kaohsiung Branch

    Kaohsiung City, 83301, Taiwan

  • Chang Gung Memorial Hospital - Linkou Branch

    Taoyuan City, 333, Taiwan

  • Chung Shan Medical University Hospital

    Taichung, 402, Taiwan

  • National Taiwan University Hospital

    Taipei, 100, Taiwan

  • Taichung Veterans General Hospital

    Taichung, 407219, Taiwan

  • Taipei Veterans General Hospital

    Taipei, 11217, Taiwan

Conditions

Explore the condition pages connected to this study.

NON-SMALL CELL LUNG CARCINOMA NON-SMALL-CELL LUNG CARCINOMA