New obesity pill shows promise in early trial
NCT ID NCT06717425
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested a new daily pill called PF-07976016 in 263 adults with obesity. Participants received either the active drug or a placebo for several weeks. Researchers measured weight changes and tracked any side effects to see if the drug is safe and helps with weight loss.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
PF-07976016 (a daily pill for weight loss)
What this could lead to
If successful, this could lead to a new daily medication to help people with obesity lose weight safely.
What could go wrong
This is an early Phase 2a trial, so results may not confirm effectiveness or safety. The drug may cause side effects or fail to show meaningful weight loss compared to placebo.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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AMR Clinical
Norman, Oklahoma, 73069, United States
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Accellacare - Wilmington
Wilmington, North Carolina, 28401, United States
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Anaheim Clinical Trials, LLC
Anaheim, California, 92801, United States
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Artemis Institute for Clinical Research
San Diego, California, 92103, United States
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Canadian Phase Onward
Toronto, Ontario, M3J 0K2, Canada
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Capital Area Research, LLC
Camp Hill, Pennsylvania, 17011, United States
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Centrum Badan Klinicznych PI-House sp. z o.o.
Gdansk, Pomeranian Voivodeship, 80-546, Poland
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Centrum Medyczne Pratia Gdynia
Gdynia, Pomeranian Voivodeship, 81-338, Poland
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Centrum Zdrowia Metabolicznego Pawel Bogdanski
Poznan, Greater Poland Voivodeship, 60-589, Poland
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Chrysalis Clinical Research
St. George, Utah, 84790, United States
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Clinical & Translational Research Center
Aurora, Colorado, 80045, United States
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Consano Clinical Research, LLC
Shavano Park, Texas, 78231, United States
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Cornerstone Nutrition and Diabetes
Norman, Oklahoma, 73069, United States
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Cotton O'Neil Diabetes & Endocrinology
Topeka, Kansas, 66606, United States
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Dawson Clinical Research Inc.
Guelph, Ontario, N1H 1B1, Canada
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East-West Medical Research Institute
Honolulu, Hawaii, 96814, United States
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Ekamed
Lublin, Lublin Voivodeship, 20-718, Poland
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Elligo Clinical Research Center
Austin, Texas, 78704, United States
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L-MARC Research Center
Louisville, Kentucky, 40213, United States
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Medicome Sp. z o. o.
Oświęcim, Lesser Poland Voivodeship, 32-600, Poland
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Milestone Research Inc.
London, Ontario, N5W 6A2, Canada
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New Horizon Research Center
Miami, Florida, 33165, United States
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Ocean West Research Clinic
Surrey, British Columbia, V3Z 2N6, Canada
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Pennington Biomedical Research Center
Baton Rouge, Louisiana, 70808, United States
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Renstar Medical Research
Ocala, Florida, 34470, United States
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Renstar Medical Research
Ocala, Florida, 34471, United States
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Rochester Clinical Research, LLC
Rochester, New York, 14609, United States
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Rophe Adult and Pediatric Medicine/SKYCRNG
Union City, Georgia, 30291, United States
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Selma Medical Associates
Winchester, Virginia, 22601, United States
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Southwest Internal Medicine, PC
St. George, Utah, 84790, United States
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St Johns Center for Clinical Research
Saint Augustine, Florida, 32086, United States
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StudyMetrix Research
City of Saint Peters, Missouri, 63303, United States
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Texas Diabetes & Endocrinology, P.A.
Austin, Texas, 78749, United States
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The Wharton Medical Clinic Clinical Trials Inc.
Hamilton, Ontario, L8L 5G8, Canada
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UT Southwestern Medical Center
Dallas, Texas, 75390, United States
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University of Colorado Anschutz Medical Campus
Aurora, Colorado, 80045, United States
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Velocity Clinical Research, Dallas
Dallas, Texas, 75230, United States
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Westside Center for Clinical Research
Jacksonville, Florida, 32205, United States