One visit, two shots: study tests combining RSV and shingles vaccines
NCT ID NCT06890416
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether giving the RSV vaccine (Abrysvo) and the shingles vaccine (Shingrix) at the same doctor's visit is safe and works as well as giving them separately. About 526 adults aged 50 and older took part. Researchers measured immune responses and tracked side effects like pain, fatigue, and fever for up to 4 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- RSV prefusion F subunit vaccine (Abrysvo) and herpes zoster subunit vaccine (Shingrix)
- What this could lead to
- If successful, this could show that getting both vaccines at the same visit is safe and effective, simplifying protection against RSV and shingles for older adults.
- What could go wrong
- This is a completed Phase 3 study, but results are not yet published. Combining vaccines may cause more side effects or slightly lower immune responses than giving them separately.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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AMR Clinical
Mobile, Alabama, 36608, United States
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Alliance for Multispecialty Research, LLC
Doral, Florida, 33172, United States
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Central Research Associates
Birmingham, Alabama, 35205, United States
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Centricity Research Columbus Georgia Multispecialty
Columbus, Georgia, 31904, United States
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Centricity Research Columbus Ohio Multispecialty
Columbus, Ohio, 43213, United States
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Clinical Neuroscience Solutions Inc.
Memphis, Tennessee, 38119, United States
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Clinical Research Atlanta
Stockbridge, Georgia, 30281, United States
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Clinical Research Professionals
Chesterfield, Missouri, 63005, United States
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Clinical Research Puerto Rico
San Juan, 00909, Puerto Rico
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DM Clinical Research - Bellaire
Houston, Texas, 77081, United States
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DM Clinical Research - Philadelphia
Philadelphia, Pennsylvania, 19107, United States
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DM Clinical Research - Sugar Land
Sugar Land, Texas, 77478, United States
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De La Cruz Research Center, LLC
Miami, Florida, 33184, United States
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DelRicht Research
New Orleans, Louisiana, 70115, United States
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Diablo Clinical Research, Inc.
Walnut Creek, California, 94598, United States
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IMA Clinical Research San Antonio
San Antonio, Texas, 78229, United States
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IMA Clinical Research Warren
Warren Township, New Jersey, 07059, United States
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Jadestone Clinical Research
Silver Spring, Maryland, 20904, United States
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Kaiser Permanente
Los Angeles, California, 90027, United States
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Medical Affiliated Research Center
Huntsville, Alabama, 35801, United States
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NYU Langone Health
New York, New York, 10016, United States
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Oakland Medical Research
Troy, Michigan, 48085, United States
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Optimal Research
Peoria, Illinois, 61614, United States
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Proactive Clinical Research,LLC
Fort Lauderdale, Florida, 33308, United States
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SMS Clinical Research
Mesquite, Texas, 75149, United States
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Synexus Clinical Research US, Inc.
Chicago, Illinois, 60602, United States
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Other studies related to the condition(s) this trial covers.
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