Pfizer's new obesity shot shows promise in first human tests
NCT ID NCT07022977
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage trial tested a new weekly injection called MET233 in 144 otherwise healthy adults with overweight or obesity. The main goal was to check safety and how the drug moves through the body. Researchers also looked at different dosing schedules over several weeks. Since this is a Phase 1 study, it is too soon to know if MET233 will help with weight loss.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
MET233 (a biologic drug given as a weekly injection)
What this could lead to
If it works, this could point toward a new treatment for weight management.
What could go wrong
This is a very early Phase 1 trial focused on safety, not weight loss. The drug may not work or could have side effects. Results may not lead to a marketed treatment.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Altasciences Clinical Los Angeles, Inc.
Cypress, California, 90630, United States