Can a Growth-Hormone blocker stay safe in everyday use? a korean study investigates
NCT ID NCT05131100
First seen Jul 23, 2026 · Last updated Jul 24, 2026 · Updated 1 time
Summary
This observational study tracks patients in Korea who have been prescribed Somavert (pegvisomant) for acromegaly, a condition caused by too much growth hormone. Researchers will monitor side effects and whether patients show clinical improvement during routine treatment. The goal is to see how the drug performs in real-world settings outside of controlled trials.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Somavert (pegvisomant)
- What this could lead to
- If the data confirm real-world safety and effectiveness, it may support continued use of Somavert for acromegaly in routine practice.
- What could go wrong
- This is a small observational study with only 11 participants, so findings may not apply broadly. No new treatment or comparison is being tested.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
11 people
The number who actually took part.
- Started
-
Jul 2022
- Finished
-
Nov 2025
- Lead sponsor
-
A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adult acromegaly patients who have had an inadequate response to surgery and/or radiation therapy and in whom appropriate medical treatment with somatostatin analogues did not normalize IGF-1 concentrations or was not tolerated
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: All patients who have been prescribed as per local label and investigators' judgement under the setting of routine practice in Korea who are eligible. Exclusion Criteria: Patients who are contraindicated for Somavert
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Acromegaly are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Pfizer
Seoul, South Korea
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a Once-Monthly shot tame Acromegaly's hormone overdrive?
- Which intubation method works best for acromegaly patients?
- New octreotide pill faces off against current capsule in healthy volunteer study
- New software could improve acromegaly care
- New drug MAR002 aims to tame acromegaly in early trial
- Scientists hunt for hidden genes behind pituitary tumors