Bladder cancer drug avelumab tested in Real-World setting

NCT ID NCT04822350

Completed Knowledge-focused Sponsor: Pfizer Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study tracked 596 patients in France with advanced bladder cancer who received avelumab as maintenance therapy after initial chemotherapy. Researchers observed how long patients survived and how the drug performed in everyday medical practice, rather than in a controlled trial. The goal was to gather real-world evidence on the drug's effectiveness.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

avelumab

What this could lead to

If successful, this study could confirm that avelumab maintenance therapy improves survival for advanced bladder cancer patients in everyday practice.

What could go wrong

This is an observational study, not a controlled trial, so results may be influenced by patient selection and real-world variability. It does not prove cause and effect.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

transitional cell carcinoma Urinary Bladder Neoplasms urothelial carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

UROTHELIAL CARCINOMA

Contacts and locations

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Locations

CENTRE HOSPITALIER Dr Jean-Eric TECHER

Calais, 62107, France
CHU Amiens-Picardie

Amiens, 80054, France
CHU Charles Nicolle

Rouen, Haute-normandie, 76031, France
CHU Nantes

Nantes, Pays de la Loire Region, 44093, France
CHU de Bordeaux - Hopital Saint Andre

Bordeaux, 33075, France
Centre Alexis VAUTRIN

Vandœuvre-lès-Nancy, 54511, France
Centre Antoine Lacassagne

Nice, 06189, France
Centre D'Oncologie de Gentilly

Nancy, 54100, France
Centre Hopistalier Roanne

Roanne, 42300, France
Centre Hospitalier Annecy Genevois

Epargny METZ Tessy, 74370, France
Centre Hospitalier Auxerre

Auxerre, 89000, France
Centre Hospitalier Bretagne Sud

Lorient, 56322, France
Centre Hospitalier Emile Roux

Le Puy-en-Velay, 43000, France
Centre Hospitalier Haguenau

Haguenau, 67500, France
Centre Hospitalier Intercommunal Louviers

Elbeuf, 76503, France
Centre Hospitalier Intercommunal de Creteil

Créteil, 94010, France
Centre Hospitalier Jura Sud

Lons-le-Saunier, 39000, France
Centre Hospitalier Prive Saint Gregoire

Saint-Grégoire, 35768, France
Centre Hospitalier Regional Universitaire de Brest

Brest, 29200, France
Centre Hospitalier Universitaire Gabriel Montpied

Clermont-Ferrand, 63011, France
Centre Hospitalier Universitaire de Montpellier

Montpellier, 34295, France
Centre Hospitalier Victor Dupouy

Argenteuil, 95107, France
Centre Hospitalier de Boulogne Sur Mer

Boulogne-sur-Mer, 62321, France
Centre Hospitalier de Cornouaille

Quimper, 29107, France
Centre Hospitalier de Grenoble

Greboble, 38043, France
Centre Hospitalier de Soissons

Soissons, 02200, France
Centre Hospitalier de la cote Basque

Bayonne, 64100, France
Centre Hospitalier du Pays d AIX

Aix-en-Provence, 13100, France
Centre Leon Berard

Lyon, 69373, France
Centre Leonard de Vinci

Dechy, 59187, France
Centre de Lutte Contre Le Cancer - Auvergne Jean Perrin

Clermont-Ferrand, 63011, France
Ch Roubais

Roubaix, 59100, France
Chi Alpes Du Sud

Gap, 5000, France
Chi Frejus - Saint Raphael

Fréjus, 83608, France
Chru Besancon

Besançon, 25030, France
Chu Dupuytren Service Oncologie

Limoges, 87000, France
Clinique Clement Drevon

Dijon, 21000, France
Clinique Du Mousseau

Évry, 91035, France
Clinique Mathilde

Rouen, 76100, France
Clinique Pasteur - Lanroze

Brest, 29200, France
Clinique Saint Georges

Nice, 06105, France
Clinique Sainte Anne

Strasbourg, 67000, France
Clinique Tivoli-Ducos

Bordeaux, 33000, France
Clinique Victor Hugo

Le Mans, 72015, France
Clinique de Flandre

Coudekerque-Branche, 59210, France
Clinique de la Louvière

Lille, 59042, France
Clinique de la Sauvegarde

Lyon, 69337, France
Clinique mutualiste de l Estuaire

Saint-Nazaire, 44606, France
Groupe Hospitalier Diaconesse La Croix Saint Simon

Paris, 75020, France
Groupe Hospitalier La Rochelle - Re - Aunis

La Rochelle, 17019, France
Groupe Hospitalier Mutualiste de Grenoble Institut Daniel Hollard

Grenoble, 38000, France
Hia Begin

Saint-Mandé, 94160, France
Hia Sainte Anne

Toulon, 83041, France
Hopital Cochin/Unité de Cancerologie

Paris, 75014, France
Hopital Europeen

Marseille, 13003, France
Hopital Europeen Georges Pompidou

Paris, 75908, France
Hopital Foch

Suresnes, 92151, France
Hopital Louis Pradel

Bron, 69677, France
Hopital Pitie Salpetriere

Paris, 75013, France
Hopital Prive Sainte Marie

Osny, 95520, France
Hopital Saint-Louis

Paris, 75010, France
Hopital de La Timone

Marseille, 13385, France
Hopital prive Arnault Tzanck

Mougins, 06254, France
Hopital prive du Confluent S.A.S

Nantes, 44277, France
ICANS - Institut de cancerologie Strasbourg Europe

Strasbourg, 67200, France
IUCT - Oncopole

Toulouse, 31059, France
Institut Bergonie

Bordeaux, 33076, France
Institut Gustave Roussy

Villejuif, 94805, France
Institut Jean Godinot

Reims, 51056, France
Institut Sainte Catherine

Avignon, 84918, France
Institut de Cancerologie Du Gard

Nîmes, 30900, France
Institut de Cancérologie Lucien Neuwirth

Saint-Priest-en-Jarez, 42271, France
La Roche Sur Yon - Centre Hospitalier Departemetal Vendee

La Roche-sur-Yon, 85960, France
Medipole de Savoie

Challes-les-Eaux, 73190, France
ONCOGARD

Nîmes, 30900, France
Pole Sante Republique

Clermont-Ferrand, 63050, France
Polyclinique Du Bois

Lille, 59004, France
Polyclinique Marzet

Pau, 64001, France
Polyclinique Saint Come

Compiègne, 60200, France
Polyclinique de Blois

La Chaussée-Saint-Victor, 41260, France
Polyclinique de LIMOGE-Clinique François CHENIEUX

Limoges, 87039, France