Lyme vaccine passes safety check in 3,500 kids

NCT ID NCT05634811

Completed ⭐️ VACCINE ⭐️ Sponsor: Pfizer Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a new Lyme disease vaccine (VLA15) is safe for healthy children ages 5 to 17. Over 3,500 kids received either the vaccine or a placebo (saltwater shot) and were monitored for about 2 years. The main goal was to check for side effects like pain, redness, fever, or other reactions after each of the 4 shots. The study has been completed, and the results will help decide if the vaccine can be used to prevent Lyme disease in children.

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Conditions

The condition(s) this trial relates to.

Borrelia infectious disease vector-borne disease Lyme disease prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LYME DISEASE

Contacts and locations

Locations

AMR Clinical

El Dorado, Kansas, 67042, United States
AMR Clinical

Wichita, Kansas, 67207, United States
ASR, LLC

Boise, Idaho, 83702, United States
Advanced Specialty Care

Commack, New York, 11725, United States
Advantage Clinical Trials

The Bronx, New York, 10467, United States
All Children Pediatrics

Louisville, Kentucky, 40243, United States
Allegheny Health and Wellness Pavilion

Erie, Pennsylvania, 16506, United States
Apex Research Group LLC

Fair Oaks, California, 95628, United States
Benchmark Research

Austin, Texas, 78705, United States
Benchmark Research

Fort Worth, Texas, 76135, United States
Bio-Medical Research LLC

Miami, Florida, 33144, United States
Buffalo Clinical and Translational Research Center

Buffalo, New York, 14203, United States
C & R Research Services USA

Houston, Texas, 77022, United States
Central Erie Primary Care

Erie, Pennsylvania, 16508, United States
Centricity Research Columbus Ohio Multispecialty

Columbus, Ohio, 43213, United States
Children's National Medical Center

Washington D.C., District of Columbia, 20010, United States
Clinical Research Institute

Minneapolis, Minnesota, 55402, United States
Clinical Research Partners, LLC

Richmond, Virginia, 23226, United States
Clinical Research Prime

Idaho Falls, Idaho, 83404, United States
Clinical Research Prime Rexburg

Rexburg, Idaho, 83440, United States
Coast Clinical Research, LLC

Bellflower, California, 90706, United States
Coastal Carolina Research Center

North Charleston, South Carolina, 29405, United States
DM Clinical Research - Kool Kids Pediatrics

Houston, Texas, 77065, United States
DiGiovanna Institute for Medical Education & Research

North Massapequa, New York, 11758, United States
ForCare Clinical Research

Tampa, Florida, 33613, United States
Frontier Clinical research

Kingwood, West Virginia, 26537, United States
GCP Research, Global Clinical professionals

St. Petersburg, Florida, 33705, United States
Great Lakes Research Institute

Southfield, Michigan, 48075, United States
Hassman Research Institute

Marlton, New Jersey, 08053, United States
IMA Clinical Research Warren

Warren Township, New Jersey, 07059, United States
Kentucky Pediatric/ Adult Research

Bardstown, Kentucky, 40004, United States
Lakeview Clinical Research

Guntersville, Alabama, 35976, United States
MD Medical Research

Oxon Hill, Maryland, 20745, United States
MOORE Clinical Research, Inc. d/b/a TrueBlue Clinical Research

Tampa, Florida, 33609, United States
Michigan Center of Medical Research (MICHMER)

Bingham Farms, Michigan, 48025, United States
NYU Langone Hospital - Long Island

Mineola, New York, 11501, United States
New England Research Associates

Bridgeport, Connecticut, 06606, United States
Northeast Clinical Trials Group

Scranton, Pennsylvania, 18510, United States
Pediatric Research of Charlottesville, LLC

Charlottesville, Virginia, 22902, United States
Preferred Primary Care Physicians, Preferred Clinical Research (Ofc 18)

Pittsburgh, Pennsylvania, 15236, United States
Preston Healthcare Services

Kingwood, West Virginia, 26537, United States
Prime Global Research

The Bronx, New York, 10456, United States
Research Your Health

Plano, Texas, 75093, United States
Rochester Clinical Research, LLC

Rochester, New York, 14609, United States
Rutgers University

New Brunswick, New Jersey, 08901, United States
Sisu BHR

Springfield, Massachusetts, 01103, United States
Smith Allergy & Asthma Specialists

Horseheads, New York, 14845, United States
Smith Allergy and Asthma Specialists

Cortland, New York, 13045, United States
Southampton Hospital

Hampton Bays, New York, 11946, United States
Stamford Therapeutics Consortium

Stamford, Connecticut, 06905, United States
Stony Brook Medicine Clinical Research Center

East Setauket, New York, 11733, United States
Stony Brook University

Stony Brook, New York, 11794, United States
Sun Research Institute

San Antonio, Texas, 78215, United States
Tekton Research, LLC.

Chamblee, Georgia, 30341, United States
Texas Health Resources

Fort Worth, Texas, 76135, United States
UAB Child Health Research Unit (CHRU)

Birmingham, Alabama, 35233, United States
University of Alabama at Birmingham - School of Medicine

Birmingham, Alabama, 35233, United States
University of Chicago Medical Center

Chicago, Illinois, 60637, United States
Upstate Global Health Institute

East Syracuse, New York, 13057, United States
Velocity Clinical Research, Binghamton

Binghamton, New York, 13905, United States
Velocity Clinical Research, Omaha

Omaha, Nebraska, 68134, United States
Velocity Clinical Research, Salt Lake City

West Jordan, Utah, 84088, United States
Velocity Clinical Research, Vestal

Vestal, New York, 13850, United States
Vida Clinical Studies, LLC

Dearborn Heights, Michigan, 48127, United States
White Oak Pediatrics

Silver Spring, Maryland, 20904, United States

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