New migraine prevention pill tested in large chinese trial

NCT ID NCT05810038

Completed Disease control Sponsor: Pfizer Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether the drug rimegepant can help prevent migraines in Chinese adults. 787 participants took either rimegepant or a placebo every other day for 12 weeks. The main goal was to see if rimegepant reduced the number of migraine days per month compared to placebo. The trial is now complete, and results will show if rimegepant is a safe and effective option for migraine prevention.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: rimegepant
What this could lead to: If successful, this could provide a new preventive treatment option for people with migraines, reducing the number of migraine days per month.
What could go wrong: This is a completed Phase 3 trial, but results are not yet published. The drug may not work better than placebo, and side effects are possible. It only tested in Chinese participants, so results may not apply to other populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

migraine disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MIGRAINE

Contacts and locations

Locations

Affiliated Hospital of Jiangsu University

Zhenjiang, Jiangsu, 212001, China
Affiliated Hospital of Jining Medical University

Jining, Shandong, 272000, China
Beijing Friendship Hospital, Capital Medical University

Beijing, Beijing Municipality, 100050, China
Chinese PLA General Hospital

Beijing, Beijing Municipality, 100853, China
Chongqing University Three Gorges Hospital

Chongqing, 404000, China
First Affiliated Hospital of Kunming Medical University

Kunming, Yunnan, 650032, China
General Hospital of Ningxia Medical Hospital

Yinchuan, Ningxia, 750003, China
Guangzhou First People's Hospital

Guangzhou, Guangdong, 510180, China
Hainan General Hospital

Haikou, Hainan, 570311, China
Hebei General Hospital

Shijiazhuang, Hebei, 050051, China
Heping Hospital Affiliated to Changzhi Medical College

Changzhi, 046000, China
Huashan Hospital Fudan University

Shanghai, Shanghai Municipality, 200040, China
Jinan Central Hospital

Jinan, Shandong, 250013, China
Lanzhou university second hospital

Lanzhou, Gansu, 730030, China
Liaocheng people's Hospital

Liaocheng, Shandong, 252000, China
Linyi People's Hospital

Linyi, Shandong, 276034, China
Peking University People's Hospital

Beijing, 100044, China
People's Hospital of Rizhao

Rizhao, Shandong, 276800, China
People's Hospital of Zhengzhou

Zhengzhou, Henan, 450014, China
Pingxiang People's Hospital

Pingxiang, Jiangxi, 337055, China
Qilu Hospital of Shandong University

Jinan, Shandong, 250012, China
Qingdao Central Hospital

Qingdao, Shandong, 266042, China
Renmin Hospital of Wuhan University

Wuhan, Hubei, 430060, China
Shaanxi Provincial People's Hospital

Xi'an, Shaanxi, 710068, China
Shanghai East Hospital

Shanghai, Shanghai Municipality, 200123, China
Shengli Oilfield Central Hospital

Dongying, Shandong, 257099, China
Sir Run Run Shaw Hospital

Hangzhou, Zhejiang, 310016, China
Subei People's Hospital of Jiangsu province

Yangzhou, Jiangsu, 225001, China
The 900th Hospital of Joint Logistics Support Force, PLA

Fuzhou, Fujian, 350025, China
The First Affiliated Hospital of Baotou Medical College

Baotou, Inner Mongolia, 014010, China
The First Affiliated Hospital of Chongqing Medical University

Chongqing, Chongqing Municipality, 400016, China
The First Affiliated Hospital of Suzhou University

Suzhou, Jiangsu, 215006, China
The First Affiliated Hospital of Xi'an Jiaotong University

Xi'an, Shaanxi, 710061, China
The First Affiliated Hosptial of Wenzhou Medical University

Wenzhou, Zhejiang, 325000, China
The First Hospital of Shanxi Medical University

Taiyuan, Shanxi, 030001, China
The First hospital of Jilin University

Changchun, Jilin, 130000, China
The People's Hospital of Liaoning Province

Shenyang, Liaoning, 110067, China
The Second Affiliated Hospital of Nanjing Medical University

Nanjing, Jiangsu, 210011, China
The Second Affiliated Hospital of Soochow University

Suzhou, Jiangsu, 215004, China
The Second Affiliated hospital of Kunming Medical University

Kunming, Yunnan, 650000, China
The Second Hospital of Jilin University

Changchun, Jilin, 130000, China
The Second People's Hospital of Lianyungang

Lianyungang, Jiangsu, 222002, China
The Second People's hospital of Hefei

Hefei, Anhui, 230011, China
The Third Xiangya Hospital of Central South University

Changsha, Hunan, 410013, China
The fourth people's hospital of chongqing

Chongqing, Chongqing Municipality, 400010, China
Tianjin Union Medical Center

Tianjin, 300000, China
Wuxi No. 2 People's Hospital

Wuxi, Jiangsu, 214043, China
Wuxi People's Hospital

Wuxi, Jiangsu, 214023, China
Xianyang Hospital of Yan'an University

Xianyang, Shaanxi, 712000, China

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