Pfizer

This study tests a new vaccine (PG4) to see if it is as safe as the current pneumococcal vaccine (Prevnar 20) in healthy infants. About 2400 babies around 2 months old will receive either the new or current vaccine at 2, 4, 6, and 12-15 months of age. The goal is to protect again…

This study tests an RSV vaccine in 130 adults aged 18-59 in Japan who have health conditions like lung or heart disease that put them at high risk for severe RSV. The goal is to see if the vaccine triggers a strong immune response and is safe. Participants receive one shot and ar…

This study tests a new medicine, PF-08634404, given alone or with chemotherapy for adults with early or locally advanced non-small cell lung cancer. The goal is to see if it can shrink tumors before surgery or prevent cancer from returning after treatment. About 120 participants …

This study tests two experimental drugs, PF-08653945 and PF-08653944, given alone or together, to help adults with overweight or obesity lose weight. About 872 participants will receive either the drugs or a placebo. The main goal is to see how much weight they lose and if the dr…

This study tests a new experimental drug (PF-08634404) combined with chemotherapy against an approved drug (pembrolizumab) plus chemotherapy for adults with advanced or recurrent endometrial cancer that has a working DNA repair system (pMMR). About 600 women will be randomly assi…

This study tracks 600 people in Korea with advanced breast cancer and a BRCA gene mutation who are prescribed Talzenna. Researchers will watch for side effects and how well the drug works in real-life medical practice, not in a controlled experiment. The goal is to confirm the dr…

This study looks at how safe and effective the drug Velsipity is when used for up to 52 weeks in people with ulcerative colitis. About 553 participants will take the 2 mg tablet as part of their regular care. The main goal is to track serious infections and other side effects, wh…

This early-stage study tests a new drug, PF-07994525, in 120 adults with advanced multiple myeloma that has returned or not responded to treatment. The main goals are to check safety, find the right dose, and see if the drug can shrink tumors. The study has two parts: first, find…

This study will monitor 3,000 adults in Korea who take NURTEC ODT 75 mg for migraines (with or without aura). The goal is to check for side effects and see how well the medicine works for stopping migraine attacks and preventing future ones. Participants must be 19 or older and f…

This early-stage study tests a new medicine, PF-08065010, in 100 healthy adults aged 18-65 to check its safety and how the body processes it. Participants receive either the drug or a placebo as a shot or IV, with some getting a single dose and others monthly doses for 3 months. …

This study checks if the antifungal itraconazole changes how the body handles a new experimental drug (PF-08642534). Healthy adults aged 18-65 will take the study drug alone and then with itraconazole. Researchers will measure drug levels and watch for side effects. The goal is t…

This study uses a tiny radioactive tag to follow a new medicine as it travels through the body. Nine healthy men will take the drug by mouth and later by IV to see how much enters the blood and how it leaves the body. The goal is to learn about the drug's behavior, not to treat a…

This study tests whether a new orally disintegrating tablet of tafamidis works the same as the current capsule in healthy adults. Thirty participants will take both forms under fasting conditions to compare drug levels in the blood. The goal is to see if the new tablet can be use…

This study looks at how different liquid versions of the drug osivelotor taste and how well they get into the bloodstream compared to a tablet. It also checks if taking the drug with food or an antacid changes absorption. About 52 healthy adults aged 18 to 65 will take part. The …

This study will observe about 30 adults in Taiwan with relapsed or refractory multiple myeloma who are taking elranatamab. Researchers want to see how well the drug works in everyday medical practice, not just in controlled trials. The study will track response rates, survival, a…

This study will use Scotland's national health records to see if babies born to mothers who received the RSV vaccine (ABRYSVO) are less likely to be hospitalized with severe RSV. Researchers will compare vaccinated and unvaccinated groups, following infants up to 12 months old. N…

This study will look at medical records from 3,000 adults with advanced bladder cancer to see how long their first treatment keeps the disease from getting worse. Researchers will also track which medicines doctors actually prescribe. This is not a new treatment trial—it simply o…

This study looks at how patients with a specific type of advanced lung cancer (ALK-positive non-small cell lung cancer) respond to the drug lorlatinib when it is used as their first treatment. Researchers will analyze information from a large database of 200 patients to see how l…

This study tracks 600 adults in Korea with HER2-positive advanced or metastatic breast cancer who are starting TUKYSA for the first time. Researchers will collect safety and effectiveness data from routine medical care to confirm the drug's real-world performance. The goal is to …

This study will observe 59 patients in Japan who receive Zavicefta for the first time to treat serious infections. It focuses on those with sepsis (a severe blood infection) or reduced kidney function. Researchers will track side effects and how well the drug works over 28 days. …

This study aims to check the safety of a cancer drug called bevacizumab (and its biosimilar version) when used by real patients with colorectal cancer in Japan. Researchers will look at the medical records of about 1,000 patients treated between 2019 and 2024 to see how often cer…