Pfizer

This study tests whether an investigational drug called tilrekimig, given as injections alongside medicated creams or ointments, can improve moderate-to-severe eczema (atopic dermatitis) in people aged 12 and older. Participants will be randomly assigned to receive either tilreki…

This phase 3 trial tests whether the experimental drug ritlecitinib can safely and effectively regrow hair in people aged 12 and older with moderate alopecia areata, a condition causing patchy hair loss. Participants take a daily capsule for 24 weeks, with some receiving placebo.…

This early-stage trial is testing an experimental oral drug called PF-08642534 in adults with obesity. The goal is to see if different doses are safe and how the body processes the drug. Participants will receive either the drug or a placebo once daily for a set period. The study…

This Phase 3 trial tests a new biologic drug (PF-08634404) plus chemotherapy against the approved drug Keytruda plus chemotherapy in 600 women with advanced or recurrent pMMR endometrial cancer. The goal is to see if the new combination helps patients live longer without their ca…

This study looks at the real-world effectiveness of the RSV vaccine Abrysvo in adults. Researchers will analyze health records from over 290,000 people to compare those who got the vaccine with those who did not. The goal is to see if the vaccine reduces hospitalizations and othe…

This study tracks 600 adults in Korea with advanced HER2-positive breast cancer who are starting TUKYSA for the first time. Researchers will monitor how well the drug works and any side effects in real-world settings, outside of controlled trials. The goal is to confirm the drug'…

This study will track 600 people in Korea with advanced breast cancer who are already being prescribed Talzenna. Researchers will watch for side effects and see how well the drug works in everyday medical practice, not in a strict research setting. The goal is to confirm the drug…

This phase 3 trial tests whether taking rimegepant once daily can prevent migraine attacks in people with chronic migraine (15 or more headache days per month). About 400 adults will receive either rimegepant or a placebo for 12 weeks, then all participants may receive rimegepant…

This study tests the safety and tolerability of rimegepant 75 mg ODT for acute migraine treatment in adults in India who have had an insufficient response, intolerance, or contraindication to triptans. About 60 participants take the drug as needed at the start of a migraine attac…

This early-stage trial tests whether the drug ponsegromab can help adults with advanced non-small cell lung cancer who are losing muscle mass (cachexia). About 80 participants will receive either ponsegromab or a placebo. The study measures changes in muscle size and physical fun…

This study will monitor the safety and effectiveness of NURTEC ODT 75 mg (rimegepant) in 3000 Korean adults with migraine. Participants will take the drug as prescribed for acute attacks or prevention. Researchers will track side effects and how well the drug works, including pai…

This phase 1 trial in 12 healthy adults tests whether eating a high-fat, high-calorie meal changes how much of the experimental drug prifetrastat enters the bloodstream. Each participant receives a single dose of prifetrastat once after a meal and once on an empty stomach, with a…

This early-stage trial is testing how an experimental drug called PF-08653945 enters the bloodstream when injected into different areas of the body. Researchers will give a single dose to adults who are overweight or obese and measure drug levels in the blood over time. The goal …

This study looks at health records of babies born in Scotland to see if those whose mothers received the RSV vaccine (ABRYSVO) during pregnancy have fewer hospital visits for RSV. No new participants are enrolled; researchers will analyze existing data. The goal is to understand …

This study investigates how the experimental cancer drug atirmociclib is processed by the body in people with mild, moderate, or severe liver disease compared to those with healthy livers. Participants receive a single oral dose of the drug, and blood samples are taken over time …

This study will observe how safe and effective the antibiotic Zavicefta is when used in everyday medical practice in Japan. It includes 59 patients with sepsis (a severe blood infection) or reduced kidney function who are receiving Zavicefta for the first time. Researchers will t…

This study looks at how different liquid versions of the drug osivelotor taste and how well they get into the blood compared to a tablet. It also checks if taking the drug with food or an antacid changes absorption. About 52 healthy adults aged 18 to 65 will take part.

This early-stage study tests a new drug called PF-08065010 in 100 healthy adults aged 18 to 65. The goal is to check its safety and how the body processes it, as a first step toward possibly treating rheumatoid arthritis and lupus. Participants receive either the drug or a placeb…