TUKYSA under the microscope: how safe is it in everyday use?

NCT ID NCT06873191

Not yet recruiting Disease control Sponsor: Pfizer Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tracks 600 adults in Korea with advanced HER2-positive breast cancer who are starting TUKYSA for the first time. Researchers will monitor how well the drug works and any side effects in real-world settings, outside of controlled trials. The goal is to confirm the drug's safety and effectiveness as part of a required post-approval review.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

TUKYSA (tucatinib)

What this could lead to

If successful, this study will confirm that TUKYSA works safely in everyday clinical practice, supporting its continued use for advanced HER2+ breast cancer.

What could go wrong

This is an observational study, not a new treatment test. It only monitors existing use, so it won't discover new cures or major breakthroughs. Results may be limited to Korean patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer breast carcinoma breast neoplasm HER2 positive breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••