One vaccine to fight five types of meningitis? pfizer tests new combo shot in teens
NCT ID NCT04440176
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This Pfizer study tested a new 5-in-1 vaccine (MenABCWY) that targets five types of meningococcal bacteria, which can cause serious infections like meningitis. The trial involved 309 healthy teens aged 11 to 14 and compared two different dosing schedules (shots 12 months apart vs. 36 months apart). Researchers measured how well the vaccine triggered an immune response and tracked any side effects. The goal is to find a safe and effective way to protect adolescents with fewer shots.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
pentavalent meningococcal vaccine (MenABCWY)
What this could lead to
If successful, this could lead to a simpler vaccination schedule that protects against five types of meningococcal disease with fewer shots.
What could go wrong
This is a Phase 2b trial with only 309 participants, so results may not apply to everyone. The vaccine may not provide long-lasting protection or could have side effects not seen in this small study.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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AMR Clinical
Mobile, Alabama, 36608, United States
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AMR Clinical
Roy, Utah, 84067, United States
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AMR Clinical
South Jordan, Utah, 84095, United States
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Benchmark Research
Fort Worth, Texas, 76135, United States
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California Research Foundation
San Diego, California, 92123, United States
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Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, 45206, United States
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Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, 45229, United States
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Coastal Carolina Research Center
North Charleston, South Carolina, 29405, United States
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Diagnostics Research Group
San Antonio, Texas, 78229, United States
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J. Lewis Research, Inc. / Foothill Family Clinic
Salt Lake City, Utah, 84109, United States
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J. Lewis Research, Inc. / Foothill Family Clinic South
Salt Lake City, Utah, 84121, United States
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Nona Pediatric Center
Orlando, Florida, 32829, United States
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Ohio Pediatric Research Association Inc.
Dayton, Ohio, 45414, United States
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Pediatric Research of Charlottesville, LLC
Charlottesville, Virginia, 22902, United States
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Texas Health Resources
Fort Worth, Texas, 76135, United States
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Utah Valley Pediatrics - Timpanogos Office
Orem, Utah, 84057, United States
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Velocity Clinical Research, Norfolk
Norfolk, Nebraska, 68701, United States
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Wasatch Pediatrics, Cottonwood Office
Murray, Utah, 84107, United States
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Wee Care Pediatrics
Kaysville, Utah, 84037, United States
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Wee Care Pediatrics
Syracuse, Utah, 84075, United States