New hope for Prader-Willi syndrome: growth hormone shows promise in phase 3 trial

NCT ID NCT04697381

First seen Jan 16, 2026 · Last updated May 01, 2026 · Updated 10 times

Summary

This study tested the drug somatropin (a growth hormone) in 33 Japanese people with Prader-Willi syndrome, a genetic condition that causes weak muscles, slow growth, and constant hunger. The goal was to see if somatropin could safely improve body composition by increasing lean muscle mass and reducing fat. Participants received the drug for 12 months, and changes were measured using body scans.

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Contacts and locations

Locations

  • Dokkyo Medical University Saitama Medical Center

    Koshigaya, Saitama, 343-8555, Japan

  • Hamamatsu University Hospital

    Hamamatsu, Shizuoka, 431-3192, Japan

  • Kanagawa Children's Medical Center

    Yokohama, Kanagawa, 232-8555, Japan

  • National Center for Child Health and Development

    Setagaya-ku, Tokyo, 157-8535, Japan

  • Osaka Women's and Children's Hospital

    Izumi, Osaka, 594-1101, Japan

Conditions

Explore the condition pages connected to this study.