New liquid drug offers hope for kids with severe eczema

NCT ID NCT06807281

Recruiting now Disease control Sponsor: Pfizer Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 23, 2026 · Updated 2 times

Summary

This 24-month study tests the long-term safety and effectiveness of abrocitinib, a liquid oral medication, in children aged 2 and older with moderate-to-severe atopic dermatitis (eczema). About 500 participants will receive the drug, with or without topical creams. The goal is to see if the drug can safely control eczema symptoms over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: abrocitinib (liquid oral suspension)
What this could lead to: If successful, this could provide a long-term treatment option for children with moderate-to-severe eczema, helping control symptoms and improve quality of life.
What could go wrong: This is an open-label study without a placebo group, so results may be less definitive. Side effects are possible, and the treatment requires ongoing use, not a cure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

atopic eczema Eczema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATOPIC DERMATITIS

Contacts and locations

Locations

Arkansas Research Trials
RECRUITING

North Little Rock, Arkansas, 72117, United States
Arké SMO S.A de C.V
NOT_YET_RECRUITING

Veracruz, Veracruz Ignacio de LA Llave, 91900, Mexico
Beijing Children's hospital, Capital Medical University
RECRUITING

Beijing, Beijing Municipality, 100045, China
CHUS - Hospital Clinico Universitario
RECRUITING

Santiago de Compostela, A Coruña [LA Coruña], 15706, Spain
Cahaba Dermatology & Skin Health Center
RECRUITING

Birmingham, Alabama, 35244, United States
Centrum Medyczne Angelius Provita
NOT_YET_RECRUITING

Katowice, Silesian Voivodeship, 40-611, Poland
Centrum Medyczne Evimed
RECRUITING

Warsaw, Masovian Voivodeship, 02-625, Poland
Clinexpert Kft.
RECRUITING

Budapest, Pest County, 1033, Hungary
DERMAPOLIS Medical Dermatology Center dr n. med. Edyta Gebska
RECRUITING

Chorzów, Silesian Voivodeship, 41-500, Poland
Dawes Fretzin Clinical Research Group, LLC
RECRUITING

Indianapolis, Indiana, 46250, United States
Dermatology Hospital of Jiangxi Province
NOT_YET_RECRUITING

Nanchang, Jiangxi, 330000, China
Dermatology and Ophthalmology Kume Clinic
RECRUITING

Sakai, Osaka, 593-8324, Japan
Dermedic Jacek Zdybski
RECRUITING

Ostrowiec Świętokrzyski, Świętokrzyskie Voivodeship, 27-400, Poland
Dermoklinika - Centrum Medyczne spółka cywilna M. Kierstan, J. Narbutt, A. Lesiak
RECRUITING

Lodz, Łódź Voivodeship, 90-436, Poland
Eukarya Pharmasite S.C.
NOT_YET_RECRUITING

Monterrey, Nuevo León, 64718, Mexico
Fukuoka National Hospital
RECRUITING

Fukuoka, 811-1394, Japan
Hangzhou Third People's Hospital
RECRUITING

Hangzhou, Zhejiang, 310009, China
Hospital General de Granollers
RECRUITING

Granollers, Barcelona, 08402, Spain
Hospital Universitario Miguel Servet
RECRUITING

Zaragoza, 50009, Spain
Hunan Children's Hospital
RECRUITING

Changsha, Hunan, 410007, China
Investigational Drug Service - Rady Childrens Hospital-San Diego
NOT_YET_RECRUITING

San Diego, California, 92123, United States
LUXDERM Specjalistyczny Gabinet Dermatologiczny prof. dr hab. n. med. Dorota Krasowska
RECRUITING

Lublin, Lublin Voivodeship, 20-573, Poland
Medical University of South Carolina
RECRUITING

Charleston, South Carolina, 29425, United States
Pécsi Tudományegyetem Klinikai Központ
RECRUITING

Pécs, Baranya, 7632, Hungary
Queen's square Medical Facilities Queen's square Dermatology and Allergology
RECRUITING

Yokohama, Kanagawa, 220-6208, Japan
Saruta Dermatology Clinic
NOT_YET_RECRUITING

Fukuoka, 819-0042, Japan
Sasamoto Children's Clinic
RECRUITING

Setagaya-ku, Tokyo, 157-0066, Japan
Servicios Hospitalarios de Mexico S.A. DE C.V.
NOT_YET_RECRUITING

Chihuahua City, 31238, Mexico
Shanghai Children's Hospital
RECRUITING

Shanghai, 200062, China
Shenzhen Children's Hospital
RECRUITING

Shenzhen, Guangdong, 518026, China
Solutions Through Advanced Research
RECRUITING

Jacksonville, Florida, 32256, United States
Texas Dermatology and Laser Specialists
NOT_YET_RECRUITING

San Antonio, Texas, 78235, United States
Tribe Clinical Research, LLC
RECRUITING

Greenville, South Carolina, 29607, United States
Universitaetsklinikum Carl Gustav Carus, Technischen Universitaet Dresden
NOT_YET_RECRUITING

Dresden, Saxony, 01307, Germany
University of California, San Diego/ Rady Children's Hospital - San Diego
NOT_YET_RECRUITING

San Diego, California, 92123, United States
Universitätsklinikum Münster
NOT_YET_RECRUITING

Münster, North Rhine-Westphalia, 48149, Germany
Xinhua Hospital Affiliated to Shanghai JiaoTong University School of Medicine
RECRUITING

Shanghai, 200092, China

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