New lung cancer drug shows promise in early trial

NCT ID NCT07489066

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new medicine called PF-08634404, given alone or with chemotherapy, for adults with early or locally advanced non-small cell lung cancer. The trial has three parts: before surgery, after surgery if cancer remains, or after chemoradiation. Researchers will check safety and how well the drug shrinks or controls the cancer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

PF-08634404 (also known as SSGJ-707), a biologic drug given by infusion, sometimes with chemotherapy

What this could lead to

If successful, this could offer a new treatment option for non-small cell lung cancer, potentially shrinking tumors before surgery or controlling cancer after standard therapy.

What could go wrong

This is an early Phase 2 study with only 120 participants, so results may not apply to everyone. The drug may cause side effects or not work better than existing treatments.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

carcinoma lung cancer lung disorder lung neoplasm non-small cell lung carcinoma non-small cell squamous lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hope and Healing Clinical Research

    RECRUITING

    Hinsdale, Illinois, 60521, United States

  • Hope and Healing Clinical Research

    RECRUITING

    New Lenox, Illinois, 60451, United States

  • Pan American Center for Oncology Trials, LLC - Manati Office

    RECRUITING

    Manati, 00674, Puerto Rico