Cure My Disease

Don't miss your cure!

 Log in / Sign up

New drug shows promise for rare muscle diseases

NCT ID NCT06698796

Recruiting now Disease control Sponsor: Pfizer Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests the long-term safety and effectiveness of dazukibart in people with dermatomyositis or polymyositis, rare diseases that cause muscle weakness and rashes. Participants who completed a previous study can join. Some will receive the drug via IV every 4 weeks for about a year, while others will only have safety check-ups. The goal is to see if dazukibart can help control symptoms over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

dazukibart (a drug given as an IV infusion every 4 weeks)

What this could lead to

If successful, this could provide a long-term treatment option to control muscle inflammation and improve daily function for people with dermatomyositis or polymyositis.

What could go wrong

This is an extension study, so it builds on earlier results. However, it is still testing safety and efficacy, and not all participants will receive the drug. Side effects or lack of benefit are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for DERMATOMYOSITIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

acquired idiopathic inflammatory myopathy dermatomyositis polymyositis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DERMATOMYOSITIS POLYMYOSITIS

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - Glendale

    RECRUITING

    Glendale, Arizona, 85306, United States

  • Anhui Provincial Hospital

    RECRUITING

    Hefei, Anhui, 230071, China

  • Arthritis & Rheumatology Research Institute, PLLC

    NOT_YET_RECRUITING

    Allen, Texas, 75013, United States

  • CHARM HEALTHCARE PRIVATE LIMITED (Previously Dr Shenoy's Care Private Limited)

    RECRUITING

    Ernākulam, Kerala, 682040, India

  • Centro de Investigaciones Médicas Tucuman

    RECRUITING

    SAN M. de Tucuman, Tucumán Province, T4000AXL, Argentina

  • Chi Mei Medical Center

    NOT_YET_RECRUITING

    Tainan, 71004, Taiwan

  • Cryptex Investigación Clínica S.A. de C.V.

    RECRUITING

    Cuauhtémoc, Mexico City, 06100, Mexico

  • Debreceni Egyetem Klinikai Kozpont

    RECRUITING

    Debrecen, 4032, Hungary

  • First Affiliated Hospital of Kunming Medical University

    RECRUITING

    Kunming, Yunnan, 650032, China

  • Hacettepe Universite Hastaneleri

    RECRUITING

    Altindağ, Ankara, 06230, Turkey (Türkiye)

  • Institute of Science Tokyo Hospital

    RECRUITING

    Bunkyo-ku, Tokyo, 113-8519, Japan

  • Medical Center Artmed

    RECRUITING

    Plovdiv, 4000, Bulgaria

  • Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji

    NOT_YET_RECRUITING

    Warsaw, Masovian Voivodeship, 02-637, Poland

  • National Taiwan University Hospital

    NOT_YET_RECRUITING

    Taipei, 10002, Taiwan

  • Nerve & Muscle Center of Texas

    RECRUITING

    Houston, Texas, 77030, United States

  • Nippon Medical School Hospital

    RECRUITING

    Bunkyo-ku, Tokyo, 113-8603, Japan

  • Nova Reuma Domyslawska i Rusilowicz Spolka Partnerska Lekarza Reumatologa i Fizjoterapeuty

    RECRUITING

    Bialystok, Podlaskie Voivodeship, 15-707, Poland

  • Peking Union Medical College Hospital

    RECRUITING

    Beijing, 100730, China

  • Renji Hospital Shanghai Jiao Tong University School of Medicine

    RECRUITING

    Shanghai, Shanghai Municipality, 200001, China

  • Renji Hospital Shanghai Jiao Tong University School of Medicine

    RECRUITING

    Shanghai, Shanghai Municipality, 200127, China

  • Rheumatology & Pulmonary Clinic

    RECRUITING

    Beckley, West Virginia, 25801, United States

  • Sheba Medical Center

    RECRUITING

    Ramat Gan, Central District, 5262100, Israel

  • The Second Affiliated Hospital of Nanchang University

    RECRUITING

    Nanchang, Jiangxi, 330006, China

  • The Second Affiliated Hospital of Nanchang University

    RECRUITING

    Nanchang, Jiangxi, 330036, China