New tool could predict who will suffer from steroid side effects
NCT ID NCT04664465
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study aims to create a tool that predicts which patients with inflammatory rheumatic diseases (like rheumatoid arthritis, vasculitis, or polymyalgia rheumatica) will develop serious side effects from long-term steroid use. Researchers will collect routine medical data—such as blood tests, bone density scans, and patient history—from 300 people starting high-dose steroids. The goal is to build a simple score that helps doctors personalize treatment and reduce harm.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
glucocorticoid therapy (prednisone or equivalent)
What this could lead to
If successful, doctors could use a simple score to predict steroid side effects and tailor treatment plans for each patient.
What could go wrong
This is an observational study, not a treatment trial. The predictive score may not be accurate enough for routine use and needs further validation.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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<CHU de Poitiers
Poitiers, France
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CH Le Mans
Le Mans, 72000, France
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CH des Pays de Morlaix
Morlaix, 29672, France
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CHD Vendée
La Roche-sur-Yon, 85925, France
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CHIC Quimper
Quimper, 29000, France
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CHR d'Orléans
Orléans, 45067, France
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CHRU de Brest
Brest, 29609, France
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CHU d'Angers
Angers, 49933, France
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CHU de Nantes - Service de Médecine interne
Nantes, 44093, France
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CHU de Nantes - Service de Rhumatologie
Nantes, 44093, France
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CHU de Tours
Tours, 37044, France
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Clinique St Exupéry
Toulouse, France