New drug combo aims to fight advanced lung cancer

NCT ID NCT07227298

First seen Nov 12, 2025 · Last updated May 14, 2026 · Updated 16 times

Summary

This study tests a new medicine called PF-08634404 combined with other cancer drugs in people with advanced non-small cell lung cancer that has spread and cannot be removed by surgery. The goal is to see if the combination is safe and can shrink tumors. About 162 adults will receive the drugs through an IV at the clinic.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • BRCR Global - Tamarac

    RECRUITING

    Tamarac, Florida, 33321, United States

  • BRCR Global Puerto Rico - Hato Rey

    RECRUITING

    San Juan, 00917, Puerto Rico

  • BRCR Medical Center Inc.

    RECRUITING

    Coral Springs, Florida, 33065, United States

  • Dallas Cancer Specialists

    NOT_YET_RECRUITING

    Garland, Texas, 75042, United States

  • Highlands Oncology Group, PA

    RECRUITING

    Fayetteville, Arkansas, 72703, United States

  • Highlands Oncology Group, PA

    RECRUITING

    Rogers, Arkansas, 72758, United States

  • Highlands Oncology Group, PA

    RECRUITING

    Springdale, Arkansas, 72762, United States

  • Kansai Medical University Hospital

    RECRUITING

    Hirakata, Osaka, 573-1191, Japan

  • Kaohsiung Medical University Chung-Ho Memorial Hospital

    NOT_YET_RECRUITING

    Kaohsiung City, 807, Taiwan

  • Lumi Research

    NOT_YET_RECRUITING

    Houston, Texas, 77090, United States

  • Mackay Memorial Hospital

    NOT_YET_RECRUITING

    Taipei, 10449, Taiwan

  • Massey Cancer Center Clinical & Translational Research Lab

    RECRUITING

    Richmond, Virginia, 23298, United States

  • Mid Florida Hematology and Oncology Center

    RECRUITING

    Orange City, Florida, 32763, United States

  • National Cheng Kung University Hospital

    NOT_YET_RECRUITING

    Tainan, 704, Taiwan

  • National Taiwan University Hospital

    NOT_YET_RECRUITING

    Taipei, 100, Taiwan

  • Oncology Associates of Oregon, P.C.

    RECRUITING

    Eugene, Oregon, 97401, United States

  • Pan American Center for Oncology Trials, LLC

    RECRUITING

    Rio Piedras, 00935, Puerto Rico

  • Providence Medical Foundation

    RECRUITING

    Fullerton, California, 92835, United States

  • Providence St. Jude Medical Center

    RECRUITING

    Fullerton, California, 92835, United States

  • Providence St. Jude Medical Center - Virginia K. Crosson Cancer Center and Infusion Center

    RECRUITING

    Fullerton, California, 92835, United States

  • Rocky Mountain Cancer Centers, LLP

    RECRUITING

    Denver, Colorado, 80218, United States

  • Shizuoka Cancer Center

    RECRUITING

    Nagaizumi-cho, Shizuoka, 411-8777, Japan

  • Southwest Oncology Associates

    NOT_YET_RECRUITING

    Houston, Texas, 77030, United States

  • Taipei Veterans General Hospital

    NOT_YET_RECRUITING

    Taipei, 11217, Taiwan

  • US Oncology Investigational Products Center (IPC)

    RECRUITING

    Irving, Texas, 75063, United States

  • VCU Health Community Memorial Hospital

    RECRUITING

    South Hill, Virginia, 23970, United States

  • VCU Health Stony Point

    RECRUITING

    Richmond, Virginia, 23235, United States

  • VCU Health Tappahannock Hospital

    RECRUITING

    Tappahannock, Virginia, 22560, United States

  • VCU Medical Center Gateway Building

    RECRUITING

    Richmond, Virginia, 23219, United States

  • Virginia Commonwealth University

    RECRUITING

    Richmond, Virginia, 23219, United States

  • Virginia Commonwealth University

    RECRUITING

    Richmond, Virginia, 23298, United States

  • Voyage Clinical

    NOT_YET_RECRUITING

    Sugar Land, Texas, 77479, United States

Conditions

Explore the condition pages connected to this study.