Weekly shot could transform bleeding prevention for kids with hemophilia

NCT ID NCT05611801

Recruiting now Disease control Sponsor: Pfizer Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 11, 2026 · Updated 2 times

Summary

This study tests a new medicine called marstacimab in children aged 1 to 17 with severe hemophilia A or B. The medicine is given as a weekly shot under the skin to prevent bleeding episodes. Researchers will compare how well it works to the children's own past year of standard treatment. The goal is to see if marstacimab can reduce bleeds and improve daily life.

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Conditions

The condition(s) this trial relates to.

hemophilia A hemophilia B Hemorrhage severe hemophilia A

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEMOPHILIA A HEMOPHILIA B

Contacts and locations

Locations

Aarhus Universitetshospital, Skejby
RECRUITING

Aarhus N, 8200, Denmark
Aarhus University
RECRUITING

Aarhus N, DK-8200, Denmark
Adana Acibadem Hastanesi Pediatrik Hematoloji Bilim Dali
RECRUITING

Adana, 01130, Turkey (Türkiye)
Arbesu Hematología
RECRUITING

Mendoza, M5501, Argentina
Arké SMO S.A de C.V
RECRUITING

Veracruz, 91900, Mexico
Azienda Ospedaliero Universitaria di Parma
RECRUITING

Parma, 43126, Italy
Azienda Ospedaliero-Universitaria Città della Salute e della Scienza di Torino
RECRUITING

Torino, 10126, Italy
Beijing Children's hospital, Capital Medical University
RECRUITING

Beijing, Beijing Municipality, 100045, China
Birmingham Children's Hospital
RECRUITING

Birmingham, B4 6NH, United Kingdom
Centro Estadual de Hemoterapia e Hematologia Marcos Daniel Santos - HEMOES
ACTIVE_NOT_RECRUITING

Maruípe, Vitória, 29047-105, Brazil
Charité Campus Virchow-Klinikum
RECRUITING

Berlin, 13353, Germany
Charlotte Maxeke Johannesburg Academic Hospital
ACTIVE_NOT_RECRUITING

Johannesburg, Gauteng, 2193, South Africa
Detska fakultna nemocnica Kosice
RECRUITING

Košice, 040 11, Slovakia
Detska nemocnice FN Brno
RECRUITING

Brno, Brno-město, 613 00, Czechia
Ege Universitesi Tip Fakultesi Hastanes
RECRUITING

Izmir, 35100, Turkey (Türkiye)
Ege University
RECRUITING

Izmir, 35010, Turkey (Türkiye)
Erciyes University Faculty of Medicine Pediatric
RECRUITING

Kayseri, 38039, Turkey (Türkiye)
Erciyes University Health Application and Research Center Directorate
RECRUITING

Melikgazi, Kayseri, 38039, Turkey (Türkiye)
Evelina London Children's Hospital
RECRUITING

London, SE1 7EH, United Kingdom
Fakultni nemocnice Brno
RECRUITING

Brno, 625 00, Czechia
Freeman Hospital
RECRUITING

Newcastle upon Tyne, NE7 7DN, United Kingdom
Gazi Universitesi Tip Fakultesi Hastanesi Cocuk Hematologi Bolumu
RECRUITING

Ankara, 06560, Turkey (Türkiye)
Gazi University Health Research and Application Center Gazi Hospital
RECRUITING

Ankara, 06560, Turkey (Türkiye)
Gazi University Medical Faculty
RECRUITING

Ankara, 06500, Turkey (Türkiye)
Hamilton Health Sciences - McMaster University/McMaster Children's Hospital
RECRUITING

Hamilton, Ontario, L8N 3Z5, Canada
Hospital Universitario La Paz
RECRUITING

Madrid, Madrid, Comunidad de, 28046, Spain
Hospital Universitario Miguel Servet
RECRUITING

Zaragoza, 50009, Spain
Hyogo prefectural Kobe Children's Hospital
RECRUITING

Kobe, Hyōgo, 650-0047, Japan
Hôpital Universitaire Necker Enfants Malades
RECRUITING

Paris, 75015, France
IRCCS Istituto Giannina Gaslini
RECRUITING

Genoa, Liguria, 16147, Italy
Institute of hematology&blood disease hospital
RECRUITING

Tianjin, Tianjin Municipality, China
Intermountain - Primary Children's Hospital
RECRUITING

Salt Lake City, Utah, 84113, United States
Istanbul Universitesi Istanbul Tıp Fakultesi Hastanesi
RECRUITING

Istanbul, İ̇stanbul, 34093, Turkey (Türkiye)
Istituto Clinico Humanitas - Humanitas Mirasole SPA
RECRUITING

Rozzano, Milan, 20089, Italy
Jiangxi Provincial People's Hospital
RECRUITING

Nanchang, Jiangxi, 330006, China
K. J. Somaiya Hospital and Research Centre, Somaiya Ayurvihar Complex
RECRUITING

Mumbai, Maharashtra, 400022, India
King Fahad Specialist Hospital
TERMINATED

Dammam, 32253, Saudi Arabia
Kyung Hee University Hospital at Gangdong
RECRUITING

Seoul, Seoul-teukbyeolsi [seoul], 05278, South Korea
Kyungpook National University Hospital
RECRUITING

Daegu, Taegu-kwangyǒkshi, 41944, South Korea
Medizinische Universität Wien
RECRUITING

Vienna, State of Vienna, 1090, Austria
Motol University Hospital
RECRUITING

Prague, 150 06, Czechia
Murdoch Children's Research Institute
RECRUITING

Parkville, 3052, Australia
Nagano Children's Hospital
RECRUITING

Azumino, Nagano, 399-8288, Japan
Nara Medical University Hospital
RECRUITING

Kashihara, Nara, 634-8522, Japan
National Taiwan University Hospital
RECRUITING

Taipei, 100, Taiwan
Nil Ratan Sircar Medical College and Hospital
RECRUITING

Kolkata, West Bengal, 700014, India
Nirmal Hospital Pvt Ltd.
RECRUITING

Surat, Gujarat, 395002, India
Ondokuz Mayıs Universitesi
RECRUITING

Samsun, 55200, Turkey (Türkiye)
Ospedale Pediatrico Bambino Gesù IRCCS
RECRUITING

Rome, ROMA, 00165, Italy
Rigshospitalet
RECRUITING

Copenhagen, Capital Region, 2100, Denmark
Royal Manchester Children's Hospital
RECRUITING

Manchester, M13 9WL, United Kingdom
Royal Victoria Infirmary
RECRUITING

Newcastle upon Tyne, England, NE1 4LP, United Kingdom
Saga University Hospital
RECRUITING

Saga, 849-8501, Japan
Saitama Prefectural Children's Medical Center
RECRUITING

Saitama-shi, Saitama, 330-8777, Japan
Severance Hospital, Yonsei University Health System
RECRUITING

Seoul, Seoul-teukbyeolsi [seoul], 03722, South Korea
Sheba Medical Center
RECRUITING

Ramat Gan, Central District, 5262100, Israel
Southern Medical University Nanfang Hospital
RECRUITING

Guangzhou, Guangdong, 510515, China
Stollery Children's Hospital
RECRUITING

Edmonton, Alberta, T6G 2B7, Canada
Taichung Veterans General Hospital
RECRUITING

Taichung, 407219, Taiwan
The Affiliated Hospital of Guizhou Medical University
RECRUITING

Guiyang, Guizhou, 550004, China
Tongji Hospital of Tongji Medical College of HUST/Pediatric Hematology Department Pharmacy
RECRUITING

Wuhan, Hubei, 430030, China
Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology
RECRUITING

Wuhan, Hubei, 430030, China
Univerzitna nemocnica Martin
RECRUITING

Martin, 036 59, Slovakia
Worthwhile Clinical Trials
ACTIVE_NOT_RECRUITING

Benoni, Gauteng, 1500, South Africa

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