New drug could ease rare muscle disease – pfizer launches major trial

NCT ID NCT05895786

Recruiting now Disease control Sponsor: Pfizer Source: ClinicalTrials.gov ↗

First seen Oct 31, 2025 · Last updated May 23, 2026 · Updated 24 times

Summary

This study tests an experimental drug called dazukibart for people with active dermatomyositis or polymyositis, rare diseases that cause muscle weakness and sometimes skin rash. About 318 adults will receive either the drug or a placebo by IV every 4 weeks for 48 weeks, while continuing their usual medications. The goal is to see if dazukibart safely improves muscle strength and skin symptoms.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

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Locations

200 UCLA Medical Plaza
RECRUITING

Los Angeles, California, 90095, United States
5 Wojskowy Szpital Kliniczny z Polikliniką SPZOZ
RECRUITING

Krakow, Lesser Poland Voivodeship, 30-901, Poland
Ajou University Hospital
RECRUITING

Suwon, Kyǒnggi-do, 16499, South Korea
Anhui Provincial Hospital
RECRUITING

Hefei, Anhui, 230001, China
Ankara University Ibni Sina Hospital
RECRUITING

Ankara, 06230, Turkey (Türkiye)
Arizona Arthritis & Rheumatology Research, PLLC
RECRUITING

Glendale, Arizona, 85306, United States
Arthritis & Rheumatology Research Institute, PLLC
RECRUITING

Allen, Texas, 75013, United States
Azienda Ospedaliera Universitaria Careggi
RECRUITING

Florence, 50139, Italy
Azienda Ospedaliero Universitaria Policlinico G.Rodolico-San Marco Di Catania
RECRUITING

Catania, 95121, Italy
Biopharma Informatic, LLC
NOT_YET_RECRUITING

Katy, Texas, 77494, United States
Boca Clinical Trials Mexico S.C.
NOT_YET_RECRUITING

Guadajalara, Jalisco, 44600, Mexico
Brigham and Women's Hospital
RECRUITING

Boston, Massachusetts, 02115, United States
CER medical Institute
RECRUITING

Quilmes, Buenos Aires F.D., B1878, Argentina
CHARM HEALTHCARE PRIVATE LIMITED (Previously Dr Shenoy's Care Private Limited)
RECRUITING

Kochi, Kerala, 682040, India
CITER Centro de Investigacion y Tratamiento de las Enfermedades Reumáticas S.A. de C.V.
NOT_YET_RECRUITING

Mexico City, 06700, Mexico
CITER Centro de Investigación y Tratamiento de las Enfermedades Reumáticas
NOT_YET_RECRUITING

Mexico City, Mexico City, 06700, Mexico
CTC - Brigham & Women's Hospital
RECRUITING

Boston, Massachusetts, 02115, United States
CTH - Brigham & Women's Hospital
RECRUITING

Boston, Massachusetts, 02115, United States
Cangzhou People's Hospital
RECRUITING

Cangzhou, Hebei, 061011, China
Center for Clinical Research - Chapman Pavilion
ACTIVE_NOT_RECRUITING

Orange, California, 92868, United States
Centre Hospitalier Universitaire de Reims - l'Hôpital Maison Blanche
RECRUITING

Reims, 51092, France
Centro Integral en Reumatologia
NOT_YET_RECRUITING

Guadalajara, Jalisco, 44160, Mexico
Centro de Investigaciones Médicas Tucuman
RECRUITING

SAN M. de Tucuman, Tucumán Province, T4000AXL, Argentina
Centrum Medycyny Oddechowej Robert Mroz spolka jawna
RECRUITING

Bialystok, Podlaskie Voivodeship, 15-044 Bialystok, Poland
Centrum Medyczne Plejady
RECRUITING

Krakow, Lesser Poland Voivodeship, 30-363, Poland
Chang Gung Medical Foundation-Linkou Branch
RECRUITING

Taoyuan, 333, Taiwan
Chi Mei Medical Center
RECRUITING

Tainan, Tainan, 71004, Taiwan
China Medical University Hospital
RECRUITING

Taichung, 404332, Taiwan
China-Japan Friendship Hospital
RECRUITING

Beijing, Beijing Municipality, 100029, China
Chonnam National University Bitgoeul Hospital
RECRUITING

Gwangju, Kwangju-kwangyokshi, 61748, South Korea
Cleveland Clinic
RECRUITING

Cleveland, Ohio, 44195, United States
Cryptex Investigación Clínica S.A. de C.V.
RECRUITING

Cuauhtémoc, Mexico City, 06100, Mexico
Debreceni Egyetem Klinikai Kozpont
RECRUITING

Debrecen, 4032, Hungary
Diagnostic Consultative Center - Fokus-5 - Medical Establishment for Outpatient Care OOD
RECRUITING

Sofia, Sofia (stolitsa), 1463, Bulgaria
Doncaster Royal Infirmary
RECRUITING

Doncaster, DN2 5LT, United Kingdom
Dongguan People's Hospital
RECRUITING

Dongguan, Guangdong, 523016, China
Dongguan People's Hospital
RECRUITING

Dongguan, 523059, China
First Affiliated Hospital of Kunming Medical University
RECRUITING

Kunming, Yunnan, 650032, China
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
RECRUITING

Roma, RM, 00168, Italy
Guangdong Provincial People's Hospital
RECRUITING

Guangzhou, Guangdong, 510080, China
Hacettepe Universite Hastaneleri
RECRUITING

Ankara, 06230, Turkey (Türkiye)
Hanyang University Seoul Hospital
RECRUITING

Seoul, Seoul-teukbyeolsi [seoul], 04763, South Korea
Hopitaux Universitaires de Strasbourg, Nouvel Hopital Civil
RECRUITING

Strasbourg, 67091, France
Hospital General Universitario Gregorio Marañon
RECRUITING

Madrid, 28007, Spain
Hospital Universitario 12 de Octubre
RECRUITING

Madrid, 28041, Spain
Hospital Universitario Infanta Leonor
RECRUITING

Madrid, Madrid, Comunidad de, 28031, Spain
Hospital Universitario de Canarias
RECRUITING

San Cristóbal de La Laguna, Santa CRUZ DE Tenerife, 38320, Spain
Hospital for Special Surgery
NOT_YET_RECRUITING

New York, New York, 10021, United States
Hospital for Special Surgery - Belaire
NOT_YET_RECRUITING

New York, New York, 10021, United States
Hospital of the university of occupational and environmental health
RECRUITING

Kitakyushu-shi, Fukuoka, 807-8556, Japan
Huashan Hospital, Fudan University
RECRUITING

Shanghai, Shanghai Municipality, 200040, China
Hôpital Edouard Herriot
NOT_YET_RECRUITING

Lyon, 69003, France
Hôpitaux Universitaires Pitie Salpetriere AP-HP - CRMR des Myopathies Inflammatoires
NOT_YET_RECRUITING

Paris, 75013, France
INTER CLINIC Piotr Adrian Klimiuk
RECRUITING

Bialystok, Podlaskie Voivodeship, 15-077, Poland
IRCCS Istituto Clinico Humanitas
RECRUITING

Rozzano, Milano, 20089, Italy
IRIS Research and Development, LLC
RECRUITING

Plantation, Florida, 33324, United States
Institute of Post Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial Hospital
RECRUITING

Kolkata, West Bengal, 700020, India
Institute of Science Tokyo Hospital
RECRUITING

Bunkyo-ku, Tokyo, 113-8519, Japan
Instituto de Investigaciones Clinicas Zarate
NOT_YET_RECRUITING

Zárate, Buenos Aires, B2800DGH, Argentina
Instituto de Reumatología Medical Center S.A.
RECRUITING

Mendoza, 5500, Argentina
Integrative Rheumatology of South Texas
RECRUITING

Edinburg, Texas, 78539, United States
Integrative Rheumatology of South Texas
RECRUITING

Harlingen, Texas, 78550, United States
Irccs Ospedale San Raffaele
RECRUITING

Milan, 20132, Italy
KU Clinical Research Center - Clinical and Translational Science Unit (CTSU)
RECRUITING

Fairway, Kansas, 66205, United States
KU Clinical Research Center - Clinical and Translational Science Unit (CTSU) Rainbow
RECRUITING

Kansas City, Kansas, 66160, United States
Karolinska University Hospital Solna
RECRUITING

Stockholm, 17164, Sweden
Kyung Hee University Hospital
RECRUITING

Seoul, Seoul-teukbyeolsi [seoul], 02447, South Korea
Lal Bhagchandani, M.D
ACTIVE_NOT_RECRUITING

Margate, Florida, 33063, United States
Ludwig Maximilians University Munich Klinikum
RECRUITING

München, 80336, Germany
Lux Med
RECRUITING

Krakow, Lesser Poland Voivodeship, 30-415, Poland
Mayo Clinic Hospital
RECRUITING

Phoenix, Arizona, 85054, United States
Mayo Clinic in Arizona - Scottsdale
RECRUITING

Scottsdale, Arizona, 85259, United States
Mayo Clinic in Florida
RECRUITING

Jacksonville, Florida, 32224, United States
Małopolskie Centrum Kliniczne
RECRUITING

Krakow, Lesser Poland Voivodeship, 30-149, Poland
Medanta-The Medicity
RECRUITING

Gurugram (Gurgaon), Haryana, 122001, India
Medical Center Artmed
RECRUITING

Plovdiv, 4002, Bulgaria
Memorial Ankara Hastanesi
RECRUITING

Ankara, 06520, Turkey (Türkiye)
NYU Langone Health
RECRUITING

New York, New York, 10016, United States
NYU Langone Health - Clinical and Translational Science Institute Research Pharmacy
RECRUITING

New York, New York, 10016, United States
NYU Langone Health Clinical Research Center
RECRUITING

New York, New York, 10016, United States
NYU Langone Radiology
RECRUITING

New York, New York, 10016, United States
Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School
RECRUITING

Nanjing, Jiangsu, 210000, China
Narodny ustav reumatickych chorob
RECRUITING

Piešťany, 921 12, Slovakia
Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji
RECRUITING

Warsaw, Masovian Voivodeship, 02-637, Poland
National Hospital Organization Osaka Minami Medical Center
RECRUITING

Kawachi-Nagano, Osaka, 586-8521, Japan
National Taiwan University Hospital
RECRUITING

Taipei, 100225, Taiwan
Nerve & Muscle Center of Texas
RECRUITING

Houston, Texas, 77030, United States
Neuromuscular Research Center
RECRUITING

Phoenix, Arizona, 85028, United States
Nippon Medical School Hospital
RECRUITING

Bunkyo-ku, Tokyo, 113-8603, Japan
Nova Reuma Domyslawska i Rusilowicz Spolka Partnerska Lekarza Reumatologa i Fizjoterapeuty
RECRUITING

Bialystok, Podlaskie Voivodeship, 15-707, Poland
Okayama City General Medical Center Okayama City Hospital
RECRUITING

Okayama, Okayama-ken, 700-8557, Japan
Omega Research Orlando
ACTIVE_NOT_RECRUITING

Orlando, Florida, 32808, United States
Peking Union Medical College Hospital
RECRUITING

Beijing, Beijing Municipality, 100730, China
Pracownia Radiologiczna WIDOK-MED
RECRUITING

Krakow, Lesser Poland Voivodeship, 30-147, Poland
Private Practice - Dr. Miguel Cortes
RECRUITING

Cuernavaca, Morelos, 62448, Mexico
Pulmonary and Sleep Center of the Valley
RECRUITING

Weslaco, Texas, 78596, United States
Pécsi Tudományegyetem Klinikai Központ
RECRUITING

Pécs, Baranya, 7632, Hungary
Qilu Hospital of Shandong University
RECRUITING

Jinan, Shandong, 250012, China
Queen Elizabeth University Hospital
RECRUITING

Glasgow, Glasgow CITY, G51 4TF, United Kingdom
RAO Research LLC
NOT_YET_RECRUITING

Oklahoma City, Oklahoma, 73116, United States
Rabin Medical Center
RECRUITING

Petah Tikva, Central District, 4941492, Israel
Rheumatology & Pulmonary Clinic
RECRUITING

Beckley, West Virginia, 25801, United States
Ruijin Hospital Shanghai Jiaotong University School of Medicine
RECRUITING

Shanghai, Shanghai Municipality, 200025, China
Salford Royal Hospital
RECRUITING

Salford, Manchester, M6 8HD, United Kingdom
Seoul National University Hospital
RECRUITING

Seoul, 03080, South Korea
Shanghai Jiaotong University School of Medicine, Renji Hospital
RECRUITING

Shanghai, Shanghai Municipality, 200001, China
Shanghai Jiaotong University School of Medicine, Renji Hospital
RECRUITING

Shanghai, Shanghai Municipality, 200127, China
Sheba Medical Center
RECRUITING

Ramat Gan, Central District, 5265601, Israel
Shiga University of Medical Science Hospital
RECRUITING

Ōtsu, Shiga, 520-2192, Japan
Sourasky Medical Center
RECRUITING

Tel Aviv, TELL ABĪB, 6423906, Israel
St. Marianna University School of Medicine Hospital
RECRUITING

Kawasaki, Kanagawa, 216-8511, Japan
Taichung Veterans General Hospital
RECRUITING

Taichung, 40705, Taiwan
Taipei Veterans General Hospital
RECRUITING

Taipei, 11217, Taiwan
The Second Affiliated Hospital of Nanchang University
RECRUITING

Nanchang, Jiangxi, 330006, China
The Second Affiliated Hospital of Nanchang University
RECRUITING

Nanchang, Jiangxi, 330036, China
The first Affiliated Hospital, Zhejiang University School of Medicine
RECRUITING

Hangzhou, Zhejiang, 310002, China
The first Affiliated Hospital, Zhejiang University School of Medicine
RECRUITING

Hangzhou, Zhejiang, 310003, China
Tianjin Medical University General Hospital
RECRUITING

Tianjin, Tianjin Municipality, 300052, China
Tohoku University Hospital
RECRUITING

Sendai, Miyagi, 980-8574, Japan
Tokyo Medical University Hospital
RECRUITING

Shinjuku-ku, Tokyo, 160-0023, Japan
Twoja Przychodnia PCM
RECRUITING

Poznan, Greater Poland Voivodeship, 60-324, Poland
UCI Douglas Hospital
ACTIVE_NOT_RECRUITING

Orange, California, 92868, United States
UCI Health Center for Innovative Health Therapies
ACTIVE_NOT_RECRUITING

Orange, California, 92868, United States
UCLA
RECRUITING

Los Angeles, California, 90095, United States
UCLA Clinical & Translational Research Center (CTRC)
RECRUITING

Los Angeles, California, 90095, United States
UPMC Arthritis and Autoimmunity Center, Falk Clinic
RECRUITING

Pittsburgh, Pennsylvania, 15213, United States
UPMC Montefiore Clinical and Translational Research Center (CTRC)
RECRUITING

Pittsburgh, Pennsylvania, 15213, United States
UPMC Presbyterian Shadyside Hospital
RECRUITING

Pittsburgh, Pennsylvania, 15213, United States
Universitaetsklinikum Erlangen
NOT_YET_RECRUITING

Erlangen, Bavaria, 91054, Germany
University of California - Irvine
ACTIVE_NOT_RECRUITING

Orange, California, 92868, United States
University of Kansas Medical Center
RECRUITING

Kansas City, Kansas, 66160, United States
University of Kansas Medical Center - Hoglund Brain Imaging Center
RECRUITING

Kansas City, Kansas, 66160, United States
University of Miami
RECRUITING

Miami, Florida, 33125, United States
University of Miami
RECRUITING

Miami, Florida, 33136, United States
University of Miami Dermatology Clinical Trials Unit
RECRUITING

Miami, Florida, 33136, United States
University of Yamanashi Hospital
RECRUITING

Chuo-shi, Yamanashi, 409-3898, Japan
Unviversity of Miami
RECRUITING

Miami, Florida, 33136, United States
Wakayama Medical University Hospital
RECRUITING

Wakayama, 641-8510, Japan
Washington University Pulmonary Function Laboratory
ACTIVE_NOT_RECRUITING

St Louis, Missouri, 63110, United States
Washington University School of Medicine
ACTIVE_NOT_RECRUITING

St Louis, Missouri, 63110, United States
West Broward Pulmonary Consultants
RECRUITING

Plantation, Florida, 33324, United States
West Broward Rheumatology Associates
ACTIVE_NOT_RECRUITING

Tamarac, Florida, 33321, United States
West China Hospital, Sichuan University
RECRUITING

Chengdu, Sichuan, 610041, China
Xiangya Hospital Central South University
RECRUITING

Changsha, Hunan, 410008, China
Yamaguchi University Hospital
RECRUITING

Ube, Yamaguchi, 755-8505, Japan
Zaklad Diagnostyki Obrazowej HEM s.c.
RECRUITING

Bialystok, Podlaskie Voivodeship, 15-369, Poland

Conditions

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MYOSITIS