New hope for advanced cancers? pfizer launches early trial of PF-08046033

NCT ID NCT07519655

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage study tests a new medicine called PF-08046033 in adults with advanced lung, esophageal, or skin cancers that have spread or can't be removed. The main goal is to check safety and find the right dose. Researchers will also look for early signs that the drug may help control the cancer. About 250 people will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cutaneous melanoma esophageal cancer Esophageal Neoplasms esophageal squamous cell carcinoma lung neoplasm melanoma non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hospital Oncologico Dr. Isaac Gonzalez-Martinez

    RECRUITING

    Rio Piedras, 00935, Puerto Rico

  • Pan American Center for Oncology Trials, LLC

    RECRUITING

    Rio Piedras, 00935, Puerto Rico

  • Presbyterian/St Lukes Medical Center

    RECRUITING

    Denver, Colorado, 80218, United States

  • SCRI Oncology Partners

    NOT_YET_RECRUITING

    Nashville, Tennessee, 37203, United States

  • Sarah Cannon Research Institute at HealthONE

    RECRUITING

    Denver, Colorado, 80218, United States

  • Sarah Cannon Research Institute- Pharmacy

    NOT_YET_RECRUITING

    Nashville, Tennessee, 37203, United States