Can a double dose of this pill regrow hair in severe alopecia?

NCT ID NCT06873945

Ongoing Disease control Sponsor: Pfizer Source: ClinicalTrials.gov ↗

First seen Oct 31, 2025 · Last updated May 14, 2026 · Updated 29 times

Summary

This study tests two doses (50 mg and 100 mg) of the medicine ritlecitinib, taken once daily, for severe alopecia areata—a condition causing significant hair loss on the scalp, face, and body. About 550 people aged 12 and older with at least 50% scalp hair loss will be randomly assigned to one of the two doses. The study lasts about 13 months and compares results to data from previous studies to see if the higher dose is safe and works better.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Locations

AMR Clinical

Layton, Utah, 84041, United States
AUDIKA

Córdoba, Andalusia, 14001, Spain
Alliance for Multispecialty Research, LLC

Fort Myers, Florida, 33912, United States
Alliance for Multispecialty Research, LLC

Myrtle Beach, South Carolina, 29588, United States
Apex Clinical Research Center - Canton

Canton, Ohio, 44718, United States
Arlington Research Center

Arlington, Texas, 76011, United States
Beijing Children's hospital, Capital Medical University

Beijing, Beijing Municipality, 100045, China
Beijing Friendship hospital, Capital Medical University

Beijing, 100050, China
Beijing Tongren Hospital affiliated to Capital Medical University

Beijing, 100730, China
Bexley Dermatology Research

Bexley, Ohio, 43209, United States
Brett King MD, LLC

Fairfield, Connecticut, 06824, United States
Burke Pharmaceutical Research

Hot Springs, Arkansas, 71913, United States
CHUS - Hospital Clinico Universitario

Santiago de Compostela, A Coruña [LA Coruña], 15706, Spain
CaRe Clinic

Red Deer, Alberta, T4P 1K4, Canada
California Dermatology & Clinical Research Institute

Encinitas, California, 92024, United States
Callender Center for Clinical Research

Glenn Dale, Maryland, 20769, United States
Center for Clinical Studies

Houston, Texas, 77004, United States
Center for Clinical Studies - Clear Lake

Webster, Texas, 77598, United States
Centre de Recherche Dermatologique du Quebec metropolitain

Québec, G1V 4X7, Canada
Centre de Recherche Saint-Louis

Montreal, Quebec, H1Y 3L1, Canada
Centre de Recherche Saint-Louis

Québec, Quebec, G1V 3V9, Canada
Centre de Recherche Saint-Louis

Sherbrooke, Quebec, J1G 1X9, Canada
Centre de Recherche Saint-Louis

Québec, G1V 3V9, Canada
Centre de Recherche Saint-Louis inc.

Québec, G1W 4R4, Canada
Centrum Badan Klinicznych PI-House sp. z o.o.

Gdansk, Pomeranian Voivodeship, 80-546, Poland
Centrum Medyczne Angelius Provita

Katowice, Silesian Voivodeship, 40-611, Poland
Centrum Zdrowia Dziecka i Rodziny im Jana Pawla II w Sosnowcu

Sosnowiec, Silesian Voivodeship, 41-200, Poland
Chang Gung Medical Foundation-Linkou Branch

Taoyuan, 333, Taiwan
Chang Gung Memorial Hospital at Kaohsiung

Kaohsiung Niao Sung Dist, Kaohsiung, 83301, Taiwan
Chelsea and Westminster Hospital NHS Foundation Trust

London, England, SW10 9NH, United Kingdom
Chengdu Second Municipal People's Hospital

Chengdu, Sichuan, 610017, China
China-Japan Friendship Hospital

Beijing, Beijing Municipality, 100029, China
China-Japan Friendship Hospital

Beijing, Beijing Municipality, 100192, China
Cityclinic Przychodnia Lekarsko-Psychologiczna Matusiak Spółka Partnerska

Wroclaw, Lower Silesian Voivodeship, 50-566, Poland
Clinical & Translational Research Center (CTRC)

Chapel Hill, North Carolina, 27599, United States
DERMEDIC Iwona Zdybska

Lublin, Lublin Voivodeship, 20-607, Poland
DERMEDIC Iwona Zdybska

Ostrowiec Świętokrzyski, 27-400, Poland
DJL Clinical Research, PLLC

Charlotte, North Carolina, 28211, United States
Dankook University Hospital

Cheonan-si, Chungcheongnam-do [chungnam], 31116, South Korea
Dawes Fretzin Clinical Research Group, LLC

Indianapolis, Indiana, 46250, United States
DermEffects

London, Ontario, N6H 5L5, Canada
Dermatology Associates of Plymouth Meeting

Plymouth Meeting, Pennsylvania, 19462, United States
Dermatology Research Institute

Calgary, Alberta, T2J 7E1, Canada
Dermatology Specialists of Spokane

Spokane, Washington, 99202, United States
Dermatology Treatment and Research Center

Dallas, Texas, 75230, United States
Dermatology and Skin Cancer Specialists, LLC

Rockville, Maryland, 20850, United States
Dermatology on Bloor - Research Toronto

Toronto, Ontario, M4W 2N4, Canada
Doc1 Healthcare Systems

Brea, California, 92821, United States
Doc1 Healthcare Systems

Chino, California, 91710, United States
Dr Sękowska Leczenie Bólu

Warsaw, Masovian Voivodeship, 01-018, Poland
Endeavor Health

Evanston, Illinois, 60201, United States
Endeavor Health

Skokie, Illinois, 60077, United States
Fakultni Nemocnice Plzen

Pilsen, Plzeň Region, 301 00, Czechia
First Affiliated Hospital of Kunming Medical University

Kunming, Yunnan, 650032, China
ForCare Clinical Research

Tampa, Florida, 33613, United States
GCM Medical Group, PSC - Hato Rey Site

San Juan, 00917, Puerto Rico
Grupo Pedro Jaén

Madrid, 28006, Spain
Guelph Dermatology Research

Guelph, Ontario, N1L 0B7, Canada
Guy's & St Thomas' NHS Foundation Trust

London, London, CITY of, SE1 9RT, United Kingdom
Guy's & St Thomas' NHS Foundation Trust

London, SE1 7EH, United Kingdom
Hamamatsu University Hospital

Hamamatsu, Shizuoka, 431-3192, Japan
Hangzhou Third Hospital

Hangzhou, Zhejiang, 310009, China
Hospital Universitario Miguel Servet

Zaragoza, 50009, Spain
Hospital Universitario Reina Sofia

Córdoba, Andalusia, 14004, Spain
Huashan Hospital, Fudan University

Shanghai, Shanghai Municipality, 200040, China
Icahn School of Medicine at Mount Sinai

New York, New York, 10029, United States
Innovaderm Research Inc.

Montreal, Quebec, H2X 2V1, Canada
JRB Research Inc.

Ottawa, Ontario, K1K 4L2, Canada
Jeonbuk National University Hospital

Jeonju, Jeonrabugdo, 54907, South Korea
Jiangxi Provincial Children's Hospital

Nanchang, Jiangxi, China
Johns Hopkins University

Baltimore, Maryland, 21218, United States
Juntendo Tokyo Koto Geriatric Medical Center

Koto-ku, Tokyo, 136-0075, Japan
Kaohsiung Medical University Chung-Ho Memorial Hospital

Kaohsiung City, 807, Taiwan
Klinika Osipowicz & Turkowski

Warsaw, Masovian Voivodeship, 00-716, Poland
Konkuk University Medical Center

Seoul, Seoul-teukbyeolsi [seoul], 05030, South Korea
Kozni ambulance Fialova s.r.o

Prague, Praha 6, 160 00, Czechia
Kurume University Hospital

Kurume, Fukuoka, 830-0011, Japan
Kyorin University Hospital

Mitaka, Tokyo, 181-8611, Japan
Kyung Hee University Hospital at Gangdong

Seoul, Seoul-teukbyeolsi [seoul], 05278, South Korea
Kyungpook National University Hospital

Junggu, Taegu-kwangyǒkshi, 41944, South Korea
Lynderm Research Inc.

Markham, Ontario, L3P 1X3, Canada
Marvel Clinical Research

Huntington Beach, California, 92647, United States
Massachusetts General Hospital

Boston, Massachusetts, 02114, United States
Medical University of South Carolina

Charleston, South Carolina, 29425, United States
NW Dermatology Institute

Portland, Oregon, 97210, United States
NZOZ GynCentrum - Oddział Warszawa

Warsaw, 00-124, Poland
Nanjing Medical University (NMU) - Jiangsu Province Hospital

Nanjing, 210029, China
Niigata University Medical & Dental Hospital

Niigata, 951-8520, Japan
Ninewells Hospital and Medical School

Dundee, Dundee CITY, DD1 9SY, United Kingdom
Northwest Dermatology Institute

Portland, Oregon, 97210, United States
Olympian Clinical Research - Tampa - Memorial Highway

Tampa, Florida, 33615, United States
Oregon Medical Research Center

Portland, Oregon, 97201, United States
Osaka Metropolitan University Hospital

Osaka, 545-8586, Japan
Pediatric Skin Research

Miami, Florida, 33156, United States
Peking University People's Hospital

Beijing, Beijing Municipality, 100044, China
Pratia Pardubice a.s.

Pardubice, 53002, Czechia
Principle Research Solutions

Spokane, Washington, 99202, United States
Regents of the University of Minnesota

Minneapolis, Minnesota, 55455, United States
Resonancia Magnetica Nuestra Senora del Rosario

Madrid, 28006, Spain
Revival Research Institute, LLC

Southfield, Michigan, 48034, United States
Revival Research Institute, LLC

Troy, Michigan, 48084, United States
Robert B. Pritt, DO, PA

Fort Myers, Florida, 33912, United States
Royalderm Agnieszka Nawrocka

Warsaw, Masovian Voivodeship, 02-962, Poland
Ryan Clinical Research Inc.

Newmarket, Ontario, L3Y 5G8, Canada
SKiN Centre for Dermatology

Peterborough, Ontario, K9J 5K2, Canada
Seoul Metropolitan Government Seoul National University Boramae Medical Center Laboratory

Seoul, 07061, South Korea
Seoul National University Bundang Hospital

Seongnam, Kyǒnggi-do, 13620, South Korea
Seoul National University Hospital

Seoul, Seoul-teukbyeolsi [seoul], 03080, South Korea
Shanghai Children's Hospital

Shanghai, 200062, China
SimcoDerm Medical and Surgical Dermatology Center

Barrie, Ontario, L4M 7G1, Canada
Sir Run Run Shaw Hospital of Zhejiang University School of Medicine

Hangzhou, Zhejiang, 310016, China
Skin Research of South Florida

Miami, Florida, 33173, United States
Southern California Clinical Research

Santa Ana, California, 92701, United States
Specjalistyczny Gabinet Dermatologiczny Aplikacyjno-Badawczy, Marek Brzewski, Paweł Brzewski spółka

Krakow, Lesser Poland Voivodeship, 30-002, Poland
Taipei Veterans General Hospital

Taipei, 11217, Taiwan
Texas Dermatology and Laser Specialists

San Antonio, Texas, 78218, United States
The Catholic University of Korea, Eunpyeong St. Mary's Hospital

Seoul, Seoul-teukbyeolsi [seoul], 03312, South Korea
The Centre for Clinical Trials

Oakville, Ontario, L6J 7W5, Canada
The First Affiliated Hospital of Guangzhou Medical College

Guangzhou, Guangdong, 510140, China
The General Hospital Corporation d/b/a Massachusetts General Hospital

Boston, Massachusetts, 02114, United States
The Kirklin Clinic of UAB Hospital (Radiology)

Birmingham, Alabama, 35233, United States
The Second Affiliated Hospital Chongqing Medical University

Chongqing, Chongqing Municipality, 400010, China
Tohoku University Hospital

Sendai, Miyagi, 980-8574, Japan
Tokyo Medical University Hospital

Shinjuku-ku, Tokyo, 160-0023, Japan
Tufts Medical Center

Boston, Massachusetts, 02111, United States
Twoja Przychodnia - Szczecinskie Centrum Medyczne

Szczecin, West Pomeranian Voivodeship, 71-500, Poland
Twoja Przychodnia NCM

Nowa Sól, Lubusz Voivodeship, 67-100, Poland
Twoja Przychodnia PCM

Poznan, Greater Poland Voivodeship, 60-324, Poland
University Hospitals Sussex NHS Foundation Trust

East Sussex, Brighton AND HOVE, BN2 1ES, United Kingdom
University Hospitals Sussex NHS Foundation Trust

Worthing, WEST Sussex, BN11 2DH, United Kingdom
University of Alabama at Birmingham

Birmingham, Alabama, 35233, United States
University of Alabama at Birmingham Faculty Office Towers (Regulatory)

Birmingham, Alabama, 35233, United States
University of Iowa

Iowa City, Iowa, 52242, United States
University of Minnesota Clinics and Surgery Center Department of Audiology

Minneapolis, Minnesota, 55455, United States
University of Minnesota Clinics and Surgery Center Department of Radiology

Minneapolis, Minnesota, 55454, United States
University of Minnesota Clinics and Surgery Center Department of Radiology

Minneapolis, Minnesota, 55455, United States
University of Minnesota Health Clinical Research Unit (M Health CRU)

Minneapolis, Minnesota, 55455, United States
University of North Carolina Medical Center

Chapel Hill, North Carolina, 27516, United States
University of Utah

Murray, Utah, 84107, United States
University of Utah

Salt Lake City, Utah, 84112, United States
Vital Prospects Clinical Research Institute, PC

Tulsa, Oklahoma, 74136, United States
Wiseman Dermatology Research Inc.

Winnipeg, Manitoba, R3M 3Z4, Canada
Xiangya Hospital Central South University

Changsha, Hunan, 410008, China

Conditions

Explore the condition pages connected to this study.

ALOPECIA AREATA