Can allergy and glaucoma drugs regrow hair when delivered by microneedling?

NCT ID NCT07757867

First seen Aug 11, 2026 · Last updated Aug 12, 2026 · Updated 1 time

Summary

This pilot study tests whether delivering cetirizine (an allergy medication) or latanoprost (a glaucoma drug) through microneedling can safely and effectively regrow hair in people with patchy alopecia areata. About 80 participants with recent-onset, limited patches of hair loss will be randomly assigned to one of four groups: microneedling plus cetirizine, microneedling plus latanoprost, microneedling plus triamcinolone acetonide (a standard steroid treatment), or microneedling alone. The main goal is to compare changes in scalp hair loss severity, measured by the SALT score, and to assess hair regrowth using clinical photographs.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Microneedling-assisted delivery of topical cetirizine 1% solution or latanoprost 0.01% solution, compared with microneedling plus triamcinolone acetonide (standard) and microneedling alone.
What this could lead to
If effective, this could offer a new, less invasive treatment option for patchy hair loss in alopecia areata, potentially improving hair regrowth without injections.
What could go wrong
This is a small pilot study, so results may not be conclusive or generalizable. The treatments may not outperform standard care, and side effects like skin irritation or unexpected reactions are possible.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Tanta University

    Tanta, El-Gharbia Governorate, Egypt, 31527, Egypt

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