New pill hopes to tame severe gut disease in kids
NCT ID NCT07470879
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a daily pill called etrasimod in 24 children aged 2 to 12 with moderate to severe ulcerative colitis, a chronic inflammatory bowel disease. The goal is to see if the drug can safely help children reach remission (few or no symptoms) over 52 weeks. Participants who finish may continue treatment for up to 5 years.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Etrasimod (a daily pill that helps control inflammation in the gut)
What this could lead to
If successful, this could provide a new treatment option for children with ulcerative colitis, helping them achieve and maintain remission.
What could go wrong
This is a small, early-phase study with only 24 children, so results may not apply to all patients. The drug may cause side effects or fail to show clear benefit.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Azienda Ospedaliera Universitaria Meyer IRCCS
NOT_YET_RECRUITINGFlorence, Tuscany, 50139, Italy
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CHU de Québec - Université Laval
RECRUITINGQuébec, Quebec, G1V4G2, Canada
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Centrum Zdrowia MDM
RECRUITINGWarsaw, Masovian Voivodeship, 00-189, Poland
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Children's Hospital Research Institute of Manitoba
NOT_YET_RECRUITINGWinnipeg, Manitoba, R3E 3P4, Canada
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Evelina London Children's Hospital
RECRUITINGLondon, SE1 7EH, United Kingdom
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Gyncentrum sp. z o.o. NZOZ Holsamed - oddział Libero
RECRUITINGKatowice, 40-600, Poland
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HELIOS Klinikum Wuppertal
RECRUITINGWuppertal, 42283, Germany
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Hadassah Medical Center
RECRUITINGJerusalem, Jerusalem, 9112001, Israel
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Health Sciences Centre Winnipeg
NOT_YET_RECRUITINGWinnipeg, Manitoba, R3A 1S1, Canada
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Hospices Civils de Lyon - Hôpital Femme Mère Enfant
RECRUITINGBron, Auvergne-Rhône-Alpes, 69500, France
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Hôpital Universitaire Necker Enfants Malades
NOT_YET_RECRUITINGParis, 75015, France
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Instytut "Pomnik - Centrum Zdrowia Dziecka"
RECRUITINGWarsaw, 04-730, Poland
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Japanese Red Cross Kumamoto Hospital
RECRUITINGKumamoto, 861-8520, Japan
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Juntendo University Hospital
RECRUITINGTokyo, 113-8431, Japan
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King's College Hospital
NOT_YET_RECRUITINGLondon, London, CITY of, SE5 9RL, United Kingdom
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Medical Network Spółka z o.o. WIP Warsaw IBD Point Profesor Kierkuś
RECRUITINGWarsaw, Masovian Voivodeship, 04-501, Poland
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Rambam Health Care Campus
NOT_YET_RECRUITINGHaifa, Northern District, 3109601, Israel
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Saitama Prefectural Children's Medical Center
RECRUITINGSaitama-shi, Saitama, 330-8777, Japan
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Shaare Zedek Medical Center
RECRUITINGJerusalem, Jerusalem, 9013102, Israel
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Sheba Medical Center
NOT_YET_RECRUITINGRamat Gan, Central District, 5262100, Israel
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Sheffield Children's Hospital
RECRUITINGSheffield, S10 2TH, United Kingdom
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Universitaetsklinikum Tuebingen
RECRUITINGTübingen, 72076, Germany
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Universitätsklinikum Leipzig
NOT_YET_RECRUITINGLeipzig, Saxony, 04103, Germany
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Universitätsklinikum Münster - Albert Schweitzer Campus
NOT_YET_RECRUITINGMünster, North Rhine-Westphalia, 48149, Germany
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Yitzhak Shamir Medical Center
NOT_YET_RECRUITINGẔerifin, Central District, 70300, Israel