Pfizer launches early trial of PF-07994525 for Hard-to-Treat myeloma
NCT ID NCT07426757
First seen Jun 27, 2026 · Last updated Jul 23, 2026 · Updated 2 times
Summary
This early-stage study tests a new drug, PF-07994525, in about 120 adults with advanced multiple myeloma that has come back or not responded to treatment. The main goals are to check the drug's safety, find the right dose, and see if it can shrink tumors. The study has two parts: first, finding a safe dose, then testing that dose in more people.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ADVANCED CANCER are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Arthur J.E. Child Comprehensive Cancer Centre
RECRUITINGCalgary, Alberta, T2N 5G2, Canada
-
Emory University Hospital
RECRUITINGAtlanta, Georgia, 30322, United States
-
Emory University Hospital Midtown
RECRUITINGAtlanta, Georgia, 30308, United States
-
SCRI Oncology Partners
RECRUITINGNashville, Tennessee, 37203, United States
-
Sarah Cannon Research Institute - Pharmacy
RECRUITINGNashville, Tennessee, 37203, United States
-
Sylvester Comprehensive Cancer Center
NOT_YET_RECRUITINGMiami, Florida, 33136, United States
-
Sylvester Comprehensive Cancer Center - Coral Springs
NOT_YET_RECRUITINGCoral Springs, Florida, 33065, United States
-
Sylvester Comprehensive Cancer Center - Hollywood
NOT_YET_RECRUITINGHollywood, Florida, 33021, United States
-
Sylvester Comprehensive Cancer Center - Plantation
NOT_YET_RECRUITINGPlantation, Florida, 33324, United States
-
Sylvester Comprehensive Cancer Center - Sole Mia
NOT_YET_RECRUITINGNorth Miami, Florida, 33181, United States
-
Sylvester Comprehensive Cancer Center- Kendall
NOT_YET_RECRUITINGMiami, Florida, 33176, United States
-
Sylvester Comprehensive Cancer Center- The Lennar Foundation Medical Center
NOT_YET_RECRUITINGCoral Gables, Florida, 33146, United States
-
TriStar Centennial Medical center
RECRUITINGNashville, Tennessee, 37203, United States
-
Tristar BMT
RECRUITINGNashville, Tennessee, 37203, United States
-
University of Miami Hospital and Clinics
NOT_YET_RECRUITINGMiami, Florida, 33136, United States
-
University of Miami Hospital and Clinics - Deerfield Beach
NOT_YET_RECRUITINGDeerfield Beach, Florida, 33442, United States
-
University of Miami Hospital and Clinics - Doral
NOT_YET_RECRUITINGDoral, Florida, 33166, United States
-
Winship Cancer Institute, Emory University
RECRUITINGAtlanta, Georgia, 30322, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- A lifeline for cancer caregivers: can simple phone support reduce their stress?
- Engineered immune cells take aim at Hard-to-Treat myeloma
- Can engineered immune cells outsmart Treatment-Resistant myeloma?
- A digital lifeline: could Real-Time symptom tracking transform care for kids with advanced cancer?
- Can a lower dose of a myeloma drug keep the disease in check with fewer side effects?
- Can a 30-hour e-learning course equip family doctors to deliver better palliative care?