New drug combo aims to protect vulnerable patients from severe COVID

NCT ID NCT07013474

Recruiting now Disease control Sponsor: Pfizer Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 28 times

Summary

This study tests whether a new drug called ibuzatrelvir, alone or combined with remdesivir, works better than remdesivir alone for treating COVID-19 in adults with severely weakened immune systems. About 300 participants who have mild to moderate symptoms will be followed to see if the treatment prevents hospitalization or worsening infection. The goal is to find a safer, more effective option for this high-risk group.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

AZ Sint-Jan Brugge-Oostende AV
RECRUITING

Bruges, West-vlaanderen, 8000, Belgium
Aalborg Universitetshospital, Syd
RECRUITING

Aalborg, North Denmark, 9000, Denmark
Alexandra General Hospital of Athens
RECRUITING

Athens, Attikí, 115 28, Greece
Baylor University Medical Center
NOT_YET_RECRUITING

Dallas, Texas, 75246, United States
Brigham and Women's Hospital
RECRUITING

Boston, Massachusetts, 02115, United States
CECIP - Centro de Estudos do Interior Paulista
NOT_YET_RECRUITING

Jaú, São Paulo, 17201130, Brazil
Canas Medical Center
NOT_YET_RECRUITING

Ponce, 00728, Puerto Rico
Centro Médico São Francisco
RECRUITING

Curitiba, Paraná, 80810-050, Brazil
Chonnam National University Hospital
RECRUITING

Gwangju, Kwangju-kwangyǒkshi, 61469, South Korea
Clinical Trials Center
RECRUITING

Boston, Massachusetts, 02115, United States
Clinical Trials Hub
RECRUITING

Boston, Massachusetts, 02115, United States
D&H Cancer Research Center LLC
RECRUITING

Margate, Florida, 33063, United States
Far Eastern Memorial Hospital
RECRUITING

New Taipei City, NEW Taipei, 220, Taiwan
Fujita Health University Hospital
RECRUITING

Toyoake, Aichi-ken, 470-1192, Japan
General Hospital of Athens "Laiko"
RECRUITING

Athens, Attikí, 11527, Greece
Hopital Claude Huriez - CHU de Lille
RECRUITING

Lille, NORD, 59037, France
Hospital General Universitario Dr. Balmis
RECRUITING

Alicante, 03010, Spain
Hospital Universitari Vall d'Hebron
RECRUITING

Barcelona, Barcelona [barcelona], 08035, Spain
Hospital Universitario Reina Sofia
RECRUITING

Córdoba, Andalusia, 14004, Spain
Hospital Universitario Virgen de Valme
RECRUITING

Seville, 41014, Spain
Houston Methodist Hospital
RECRUITING

Houston, Texas, 77030, United States
Hôpital Bichat - Claude-Bernard
RECRUITING

Paris, 75018, France
Instituto Nacional de Infectologia Evandro Chagas
NOT_YET_RECRUITING

Rio de Janeiro, 21040-360, Brazil
Memorial Hermann Hospital
RECRUITING

Houston, Texas, 77030, United States
Narodny onkologicky ustav
RECRUITING

Bratislava, 833 10, Slovakia
Narodny ustav detskych chorob
RECRUITING

Bratislava, Bratislava Region, 833 40, Slovakia
National Hospital Organization Kyushu Medical Center
RECRUITING

Fukuoka, 810-8563, Japan
Northwestern Memorial Hospital
RECRUITING

Chicago, Illinois, 60611, United States
Northwestern University Feinberg School of Medicine
RECRUITING

Chicago, Illinois, 60611, United States
Revive Research Institute, Inc.
RECRUITING

Farmington Hills, Michigan, 48334, United States
Rigshospitalet
RECRUITING

Copenhagen, Capital Region, 2100, Denmark
Rinku General Medical Center
RECRUITING

Izumisano, Osaka, 598-8577, Japan
Saga University Hospital
RECRUITING

Saga, 849-8501, Japan
Sakarya Training and Research Hospital
RECRUITING

Sakarya, 54100, Turkey (Türkiye)
School of Medicine Federal University of Minas Gerais
RECRUITING

Belo Horizonte, Minas Gerais, 30130-100, Brazil
Skylight Health Research, - Burlington
RECRUITING

Burlington, Massachusetts, 01803, United States
Swedish Ambulatory Infusion Center- First Hill
RECRUITING

Seattle, Washington, 98104, United States
Swedish Cancer Institute Treatment Center
RECRUITING

Seattle, Washington, 98104, United States
TRC
NOT_YET_RECRUITING

Pittsburgh, Pennsylvania, 15213, United States
TUM Klinikum
RECRUITING

München, Bavaria, 81675, Germany
Tachikawa Hospital
RECRUITING

Tachikawa, Tokyo, 190-8531, Japan
The University of Texas Health Science Center at Houston
RECRUITING

Houston, Texas, 77030, United States
UC Davis CTSC Clinical Research Center
RECRUITING

Sacramento, California, 95817, United States
UCHealth Anschutz Inpatient Pavilion - Anschutz Medical Campus
RECRUITING

Aurora, Colorado, 80045, United States
UPMC Division of Infectious Disease Clinic
NOT_YET_RECRUITING

Pittsburgh, Pennsylvania, 15213, United States
UPMC Hillman Cancer Center
NOT_YET_RECRUITING

Pittsburgh, Pennsylvania, 15232, United States
UPMC Presbyterian IDS
NOT_YET_RECRUITING

Pittsburgh, Pennsylvania, 15213, United States
UPMC Shadyside IDS
NOT_YET_RECRUITING

Pittsburgh, Pennsylvania, 15232, United States
University of California Davis Health
RECRUITING

Sacramento, California, 95817, United States
University of Cincinnati Medical Center
RECRUITING

Cincinnati, Ohio, 45219, United States
University of Colorado Anschutz Medical Campus
RECRUITING

Aurora, Colorado, 80045, United States
University of Colorado Hospital
RECRUITING

Aurora, Colorado, 80045, United States
University of Massachusetts Chan Medical School
RECRUITING

Worcester, Massachusetts, 01655, United States
Velocity Clinical Research, Savannah
RECRUITING

Savannah, Georgia, 31406, United States

Conditions

Explore the condition pages connected to this study.

COVID-19 INFECTION