Liver function and drug processing: a new study

NCT ID NCT07231991

First seen Nov 17, 2025 · Last updated Jun 19, 2026 · Updated 32 times

Summary

This study looks at how the body handles a single dose of the drug vepdegestrant in people with moderate to severe liver problems compared to healthy people. About 24 adults (ages 18-70) will take one pill and stay at the clinic for 11 days. The goal is to see if liver function affects how the drug is absorbed and removed from the body.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Clinical Pharmacology of Miami

    RECRUITING

    Miami, Florida, 33172, United States

  • Floridian Clinical Research, LLC

    RECRUITING

    Miami Lakes, Florida, 33016, United States

  • Genesis Clinical Research, LLC

    RECRUITING

    Tampa, Florida, 33603, United States

  • Orlando Clinical Research Center

    RECRUITING

    Orlando, Florida, 32809, United States

Conditions

The condition(s) this trial relates to.

liver disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.