New pill hopes to tame teen colitis

NCT ID NCT05287126

Recruiting now Disease control Sponsor: Pfizer Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jul 09, 2026 · Updated 3 times

Summary

This study tests a daily medication called etrasimod in 36 adolescents aged 12 to 17 with moderate-to-severe ulcerative colitis. The goal is to see if the drug can safely help control the disease and reduce inflammation over a year, with an option to continue treatment for up to 5 years. It is an early-phase trial, so while promising, it is not yet proven to work for all teens.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: etrasimod
What this could lead to: If successful, this could provide a new daily pill option for adolescents with ulcerative colitis to control their disease and reduce flare-ups.
What could go wrong: This is a small, early-phase study with only 36 teens, so results may not apply to everyone. The drug requires ongoing daily use and may have side effects; it is not a cure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

ulcerative colitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ULCERATIVE COLITIS

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

ACT-Midwest G1
RECRUITING

Abilene, Texas, 79606, United States
Arkansas Children's
NOT_YET_RECRUITING

Little Rock, Arkansas, 72202, United States
Arkansas Children's (IP Address)
NOT_YET_RECRUITING

Little Rock, Arkansas, 72202, United States
Arnold Palmer Hospital - Center for Digestive Health and Nutrition
RECRUITING

Orlando, Florida, 32806, United States
Boston Children's Hospital
RECRUITING

Boston, Massachusetts, 02115, United States
Centrum Zdrowia MDM
RECRUITING

Warsaw, 00-189, Poland
Consorci Corporacio Sanitaria Parc Tauli
RECRUITING

Sabadell, Barcelona, 08208, Spain
Gunma University Hospital
RECRUITING

Maebashi, Gunma, 371-8511, Japan
Gyncentrum sp. z o.o. NZOZ Holsamed - oddział Libero
NOT_YET_RECRUITING

Katowice, 40-600, Poland
Hospital Clinico Universitario de Santiago de Compostela
RECRUITING

Santiago de Compostela, A Coruna, 15706, Spain
Hospital Reina Sofia
RECRUITING

Córdoba, 14004, Spain
Hospital Universitari Vall d'Hebron
RECRUITING

Barcelona, 08035, Spain
Hyogo Medical University Hospital
RECRUITING

Nishinomiya, Hyōgo, 663-8501, Japan
Instytut "Pomnik - Centrum Zdrowia Dziecka" (IPCZD) (The Children's Memorial Health Institute)
RECRUITING

Warsaw, Masovian Voivodeship, 04-730, Poland
Instytut Centrum Zdrowia Matki Polki
ACTIVE_NOT_RECRUITING

Lodz, Łódź Voivodeship, 93-338, Poland
Ishii Eye Clinic
RECRUITING

Nagareyama-shi, Chiba, 270-0116, Japan
Japanese Red Cross Kyoto Daini Hospital
RECRUITING

Kyoto, 602-8026, Japan
Jichi Medical University Hospital
RECRUITING

Shimotsuke, Tochigi, 329 0498, Japan
Juntendo University Hospital
RECRUITING

Bunkyo-ku, Tokyo, 113-8431, Japan
K.M. Management, spol. s r.o.
RECRUITING

Nitra, 949 01, Slovakia
Kinki University - Nara Hospital
RECRUITING

Ikoma, Nara, 630-0293, Japan
Loma Linda Children's Hospital
NOT_YET_RECRUITING

Loma Linda, California, 92354, United States
Loma Linda University Children's Hospital Pediatric Specialty Clinics
NOT_YET_RECRUITING

San Bernardino, California, 92408, United States
Loma Linda University Clinical Trial Center
NOT_YET_RECRUITING

Loma Linda, California, 92354, United States
Loma Linda University Eye Institute
NOT_YET_RECRUITING

Loma Linda, California, 92354, United States
Loma Linda University Medical Center
NOT_YET_RECRUITING

Loma Linda, California, 92354, United States
Loma Linda University Pediatric Clinics
NOT_YET_RECRUITING

Loma Linda, California, 92354, United States
Saga University Hospital
RECRUITING

Saga, 849-8501, Japan
Saitama Prefectural Children's Medical Center
RECRUITING

Saitama-shi, Saitama, 330-8777, Japan
Toyama Prefectural Central Hospital
RECRUITING

Toyama, 930-8550, Japan
Tsujinaka Hospital - Kashiwanoha
RECRUITING

Kashiwa, Chiba, 277-0871, Japan
Twoja Przychodnia - Szczecińskie Centrum Medyczne
RECRUITING

Szczecin, 71-434, Poland
University Hospitals Cleveland Medical Center
RECRUITING

Cleveland, Ohio, 44106, United States
University Hospitals Cleveland Medical Center Rainbow Babies & Children's Hospital
RECRUITING

Cleveland, Ohio, 44106, United States
University of California San Francisco
RECRUITING

San Francisco, California, 94158, United States
University of California San Francisco,
RECRUITING

San Francisco, California, 94158, United States
University of California,San Francisco Pediatric ClinicalResearch Center (PCRC)
RECRUITING

San Francisco, California, 94158, United States
University of Chicago Medical Center
RECRUITING

Chicago, Illinois, 60637, United States
Uniwersytecki Szpital Dziecięcy w Krakowie
RECRUITING

Krakow, 30-663, Poland
Uniwersytecki Szpital Kliniczny im. Jana Mikulicza-Radeckiego we Wroclawiu
RECRUITING

Wroclaw, 50-369, Poland
Valley View Wellness Medical Center
RECRUITING

Garden Grove, California, 92845, United States
WIP Warsaw IBD Point Profesor Kierkus
RECRUITING

Warsaw, 00-728, Poland
WIP Warsaw IBD Point Profesor Kierkuś
RECRUITING

Warsaw, Masovian Voivodeship, 04-501, Poland
William Beaumont Hospital/Corewell Health - East
RECRUITING

Royal Oak, Michigan, 48073, United States
William Beaumont Hospitals Reference Laboratory
RECRUITING

Royal Oak, Michigan, 48073, United States

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