New pill could soothe stubborn hives when allergy meds fail

NCT ID NCT07219615

Recruiting now Symptom relief Sponsor: Pfizer Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests an experimental daily pill, ritlecitinib, for adults with chronic spontaneous urticaria (long-term itchy hives and swelling) that antihistamines don't fully control. About 200 participants will receive either 50 mg, 100 mg, or a placebo for 12 weeks, then all will get active treatment for another 12 weeks. The goal is to see if the drug safely reduces hives and itching.

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Conditions

The condition(s) this trial relates to.

chronic idiopathic urticaria Chronic Urticaria Pruritus urticaria

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC SPONTANEOUS URTICARIA

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

ALERGO-MED OŚRODEK BADAŃ KLINICZNYCH Sp. z o.o.
RECRUITING

Tarnów, 33-100, Poland
Acuro Research, Inc.
RECRUITING

Little Rock, Arkansas, 72205, United States
Allergy Centre Research
RECRUITING

Mississauga, Ontario, L4W 5G6, Canada
Allergy Research Canada Inc.
RECRUITING

Niagara Falls, Ontario, L2H 1H5, Canada
Allergy, Asthma, & Clinical Research Center
RECRUITING

Oklahoma City, Oklahoma, 73120, United States
Antelope Valley Clinical Trials
RECRUITING

Lancaster, California, 93534, United States
Asan Medical Center
RECRUITING

Seoul, Seoul-teukbyeolsi [seoul], 05505, South Korea
Asthma and Allergy Associates, PC
RECRUITING

Colorado Springs, Colorado, 80907, United States
Asthma and Allergy Center of Chicago
RECRUITING

River Forest, Illinois, 60305, United States
Beijing Friendship Hospital, Capital Medical University
RECRUITING

Beijing, Beijing Municipality, 100050, China
CaRe Clinic
RECRUITING

Red Deer, Alberta, T4P 1K4, Canada
Centre de Recherche Saint-Louis inc.
RECRUITING

Québec, G1W 4R4, Canada
Centrum Badan Klinicznych PI-House sp. z o.o.
RECRUITING

Gdansk, 80-546, Poland
Chang Gung Medical Foundation Linkou Chang Gung Memorial Hospital
RECRUITING

Taoyuan, 333423, Taiwan
Charite Universitätsmedizin Berlin Campus Benjamin Franklin
RECRUITING

Berlin, 12203, Germany
Chesapeake Clinical Research
RECRUITING

White Marsh, Maryland, 21162, United States
China Medical University Hospital
RECRUITING

Taichung, 40447, Taiwan
Chung-Ang University Hospital
RECRUITING

Seoul, Seoul-teukbyeolsi [seoul], 06973, South Korea
Clínica Gaias - Santiago
RECRUITING

Santiago de Compostela, A Coruña [LA Coruña], 15702, Spain
Complete Dermatology
RECRUITING

Sugar Land, Texas, 77479, United States
DAR Clinical Research
RECRUITING

Ottawa, Ontario, K1V 1C1, Canada
Dar Clinical Research
RECRUITING

Ottawa, Ontario, K2T 0N7, Canada
Dermatology and Ophthalmology Kume Clinic
RECRUITING

Sakai, Osaka, 593-8324, Japan
Diagnostic Consultative Center "Ascendent"
RECRUITING

Sofia, 1202, Bulgaria
Diagnostic Consultative Center 1 - Pernik
RECRUITING

Pernik, 2300, Bulgaria
Diagnostic Consultative Center Aleksandrovska
RECRUITING

Sofia, Sofia (stolitsa), 1431, Bulgaria
ETG Warszawa
RECRUITING

Warsaw, Masovian Voivodeship, 02-677, Poland
First OC Dermatology Research Inc
RECRUITING

Fountain Valley, California, 92708, United States
Hattori Dermatology Clinic
RECRUITING

Takasaki, Gunma, 370-0071, Japan
Hautarztpraxis Dres. Leitz & Kollegen
RECRUITING

Stuttgart, Baden-Wurttemberg, 70178, Germany
Helios Universitätsklinikum Wuppertal
RECRUITING

Wuppertal, 42283, Germany
Hospital Arnau de Vilanova
RECRUITING

Valencia, València, 46015, Spain
Hospital Universitario Fundacion ALcorcon
RECRUITING

Alcorcón, Madrid, 28922, Spain
Hospital Universitario Reina Sofia
NOT_YET_RECRUITING

Córdoba, Andalusia, 14004, Spain
Huashan Hospital, Fudan University
RECRUITING

Shanghai, Shanghai Municipality, 200040, China
Kern Research. Inc.
RECRUITING

Bakersfield, California, 93301, United States
Klinika Osipowicz & Turkowski Sp. z o.o.
RECRUITING

Warsaw, 00-716, Poland
Korea University Ansan Hospital
RECRUITING

Ansan-si, Kyǒnggi-do, 15355, South Korea
LUXDERM Specjalistyczny Gabinet Dermatologiczny prof. dr hab. n. med. Dorota Krasowska
RECRUITING

Lublin, 20-573, Poland
Laser Rejuvenation Clinics Edmonton D.T. Inc
RECRUITING

Edmonton, Alberta, T5J 3S9, Canada
M2M Med Badania Sp. z o.o.
RECRUITING

Chorzów, 41-500, Poland
Mackay Memorial Hospital
RECRUITING

Taipei, 10449, Taiwan
Medical Center Hera EOOD
RECRUITING

Sofia, 1510, Bulgaria
Medical Center Pulmo - 2018 EOOD
RECRUITING

Haskovo, 6300, Bulgaria
Medical Center Pulmovision
RECRUITING

Sofia, 1756, Bulgaria
Melita Medical
RECRUITING

Wroclaw, 53-611, Poland
National Taiwan University Hospital
RECRUITING

Taipei, 100225, Taiwan
Nomura Dermatology Clinic
RECRUITING

Yokohama, Kanagawa, 221-0825, Japan
Orion Clinical Research
RECRUITING

Austin, Texas, 78759, United States
Parc de Salut Mar - Hospital del Mar
RECRUITING

Barcelona, Barcelona [barcelona], 08003, Spain
Pusan National University Hospital
RECRUITING

Busan, Pusan-kwangyǒkshi, 49241, South Korea
RFSA Dermatology - San Antonio - West Avenue
RECRUITING

San Antonio, Texas, 78213, United States
Revival Research Institute, LLC
RECRUITING

Troy, Michigan, 48084, United States
Saguaro Dermatology - Phoenix
NOT_YET_RECRUITING

Phoenix, Arizona, 85008, United States
Severance Hospital, Yonsei University Health System
RECRUITING

Seoul, Seoul-teukbyeolsi [seoul], 03722, South Korea
Skin & Beauty Center - Pasadena
RECRUITING

Pasadena, California, 91105, United States
Tachikawa Dermatology Clinic
RECRUITING

Tachikawa, Tokyo, 190-0023, Japan
Taipei Medical University - Shuang Ho Hospital, Ministry of Health and Welfare
RECRUITING

New Taipei City, 23561 (R.O.C), Taiwan
The First Hospital of Hebei Medical University
RECRUITING

Shijiazhuang, Hebei, 050031, China
The First People's Hospital of Hangzhou
RECRUITING

Hangzhou, Zhejiang, 310000, China
The Third Affiliated Hospital Of Sun Yat-Sen University
RECRUITING

Guangzhou, Guangdong, 510630, China
Tianjin Medical University General Hospital
RECRUITING

Tianjin, Tianjin Municipality, 300052, China
Trialmed CRS - Warszawa
RECRUITING

Warsaw, 02-482, Poland
Universitaetsklinikum Carl Gustav Carus an der Technischen Universitaet Dresden
RECRUITING

Dresden, 01307, Germany
University of Michigan
RECRUITING

Ann Arbor, Michigan, 48109, United States
University of Miyazaki Hospital
RECRUITING

Miyazaki, 889-1692, Japan
Universitätsklinikum Leipzig
RECRUITING

Leipzig, 04103, Germany
Universitätsklinikum Münster
RECRUITING

Münster, North Rhine-Westphalia, 48149, Germany
Yokohama Queen's Tower C 8F
RECRUITING

Yokohama, Kanagawa, 220-6208, Japan