New hope for chronic hive sufferers: phase 3 drug trial shows promise

NCT ID NCT06396026

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests a new drug called TLL-018 in 440 adults with moderate-to-severe chronic hives (chronic spontaneous urticaria) that aren't controlled by standard antihistamines. Participants receive either TLL-018 or a placebo for 12 weeks to see if it reduces itching and hives better than placebo. The goal is to find a new treatment option for people who still suffer despite current medications.

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Conditions

The condition(s) this trial relates to.

chronic idiopathic urticaria Chronic Urticaria

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hospital for Skin Diseases, Institute of Dermatology, Chinese Academy of Medical Sciences

    Nanjing, Jiangsu, China